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Harini Raghu
Harini Raghu
Principal Scientist at Genentech/Roche
在 gene.com 的电子邮件经过验证
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引用次数
引用次数
年份
Low-grade inflammation as a key mediator of the pathogenesis of osteoarthritis
WH Robinson, CM Lepus, Q Wang, H Raghu, R Mao, TM Lindstrom, ...
Nature Reviews Rheumatology 12 (10), 580-592, 2016
12562016
CCL2/CCR2, but not CCL5/CCR5, mediates monocyte recruitment, inflammation and cartilage destruction in osteoarthritis
H Raghu, CM Lepus, Q Wang, HH Wong, N Lingampalli, F Oliviero, ...
Annals of the rheumatic diseases 76 (5), 914-922, 2017
3372017
IgE-mediated mast cell activation promotes inflammation and cartilage destruction in osteoarthritis
Q Wang, CM Lepus, H Raghu, LL Reber, MM Tsai, HH Wong, ...
Elife 8, e39905, 2019
1132019
Mice expressing a mutant form of fibrinogen that cannot support fibrin formation exhibit compromised antimicrobial host defense
JM Prasad, OV Gorkun, H Raghu, S Thornton, ES Mullins, JS Palumbo, ...
Blood, The Journal of the American Society of Hematology 126 (17), 2047-2058, 2015
1002015
Genetic elimination of the binding motif on fibrinogen for the S. aureus virulence factor ClfA improves host survival in septicemia
MJ Flick, XL Du, JM Prasad, H Raghu, JS Palumbo, E Smeds, M Höök, ...
Blood, The Journal of the American Society of Hematology 121 (10), 1783-1794, 2013
1002013
Nicotine drives neutrophil extracellular traps formation and accelerates collagen-induced arthritis
J Lee, A Luria, C Rhodes, H Raghu, N Lingampalli, O Sharpe, B Rada, ...
Rheumatology 56 (4), 644-653, 2017
932017
Dysregulated integrin αVβ3 and CD47 signaling promotes joint inflammation, cartilage breakdown, and progression of osteoarthritis
Q Wang, K Onuma, C Liu, H Wong, MS Bloom, EE Elliott, RRL Cao, N Hu, ...
JCI insight 4 (18), 2019
502019
Transglutaminase factor XIII promotes arthritis through mechanisms linked to inflammation and bone erosion
H Raghu, C Cruz, CL Rewerts, MD Frederick, S Thornton, ES Mullins, ...
Blood, The Journal of the American Society of Hematology 125 (3), 427-437, 2015
492015
Plasminogen is a joint‐specific positive or negative determinant of arthritis pathogenesis in mice
H Raghu, A Jone, C Cruz, CL Rewerts, MD Frederick, S Thornton, ...
Arthritis & rheumatology 66 (6), 1504-1516, 2014
302014
Urokinase plasminogen activator and receptor promote collagen-induced arthritis through expression in hematopoietic cells
S Thornton, H Raghu, C Cruz, MD Frederick, JS Palumbo, ES Mullins, ...
Blood advances 1 (9), 545-556, 2017
282017
Interleukin 4 promotes anti-inflammatory macrophages that clear cartilage debris and inhibits osteoclast development to protect against osteoarthritis
EP von Kaeppler, Q Wang, H Raghu, MS Bloom, H Wong, WH Robinson
Clinical Immunology 229, 108784, 2021
252021
Targeting the coagulation factor fibrinogen for arthritis therapy
H Raghu, M J Flick
Current pharmaceutical biotechnology 12 (9), 1497-1506, 2011
232011
The tyrosine kinase inhibitor imatinib mesylate suppresses uric acid crystal-induced acute gouty arthritis in mice
LL Reber, P Starkl, B Balbino, R Sibilano, N Gaudenzio, S Rogalla, ...
PLoS One 12 (10), e0185704, 2017
112017
Elevated synovial fluid concentration of monocyte chemoattractant Protein-1 and Interleukin-8 in dogs with osteoarthritis of the stifle
SA Kleine, RM Gogal, C George, MA Thaliath, SC Budsberg
Veterinary and Comparative Orthopaedics and Traumatology 33 (02), 147-150, 2020
72020
Tyrosine kinase inhibitor formulations for the treatment of mast cell-mediated inflammatory diseases and methods of use thereof
WH Robinson, A Postolova, H Raghu
US Patent App. 15/582,263, 2017
52017
Mice deficient in urokinase-type plasminogen activator (uPA) or uPA receptor develop significantly diminished collagen-induced arthritis
S Thornton, H Raghu, A Jone, C Cruz, CL Rewerts, MD Frederick, ...
Blood, The Journal of the American Society of Hematology 124 (21), 580-580, 2014
32014
Tyrosine kinase inhibitor formulations for the treatment of mast cell-mediated inflammatory diseases and methods of use thereof
WH Robinson, A Postolova, H Raghu
US Patent App. 16/672,086, 2020
12020
SAT0034 Nicotine Is A Potent Driver of Netosis and Accelerates Collagen-Induced Arthritis
J Lee, A Luria, C Rhodes, H Raghu, O Sharpe, W Robinson, J Sokolove
Annals of the Rheumatic Diseases 75 (Suppl 2), 676-676, 2016
2016
A CRITICAL PATHOGENIC ROLE FOR MAST CELLS IN OSTEOARTHRITIS
CM Lepus, H Raghu, LL Reber, Q Wang, M Tsai, HH Wong, ...
Patricia J. Gumport, Vice Provost for Graduate Education, 54, 2016
2016
Complement component C1q limits osteoarthritis pathology by regulating macrophage activation
H Raghu, N Lingampalli, Q Wang, H Wong, C Lepus, R Mao, ...
The Journal of Immunology 196 (1_Supplement), 124.7-124.7, 2016
2016
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