Biased opioid ligands A Faouzi, BR Varga, S Majumdar Molecules 25 (18), 4257, 2020 | 96 | 2020 |
Controlling opioid receptor functional selectivity by targeting distinct subpockets of the orthosteric site R Uprety, T Che, SA Zaidi, SG Grinnell, BR Varga, A Faouzi, ST Slocum, ... Elife 10, e56519, 2021 | 49 | 2021 |
Structure-based design of bitopic ligands for the µ-opioid receptor A Faouzi, H Wang, SA Zaidi, JF DiBerto, T Che, Q Qu, MJ Robertson, ... Nature 613 (7945), 767-774, 2023 | 42 | 2023 |
A novel mitragynine analog with low-efficacy mu opioid receptor agonism displays antinociception with attenuated adverse effects S Chakraborty, JF DiBerto, A Faouzi, SM Bernhard, AM Gutridge, ... Journal of medicinal chemistry 64 (18), 13873-13892, 2021 | 41 | 2021 |
Site selective C–H functionalization of Mitragyna alkaloids reveals a molecular switch for tuning opioid receptor signaling efficacy S Bhowmik, J Galeta, V Havel, M Nelson, A Faouzi, B Bechand, ... Nature communications 12 (1), 3858, 2021 | 28 | 2021 |
Synthesis and biological evaluation of thiophene and benzo [b] thiophene analogs of combretastatin A-4 and isocombretastatin A-4: A comparison between the linkage positions of … CV Do, A Faouzi, C Barette, A Farce, MO Fauvarque, E Colomb, L Catry, ... Bioorganic & medicinal chemistry letters 26 (1), 174-180, 2016 | 26 | 2016 |
Synthesis and pharmacology of a novel μ–δ opioid receptor heteromer-selective agonist based on the carfentanyl template A Faouzi, R Uprety, I Gomes, N Massaly, AI Keresztes, V Le Rouzic, ... Journal of medicinal chemistry 63 (22), 13618-13637, 2020 | 25 | 2020 |
Combretastatin A-4 sulfur-containing heterocyclic derivatives: Synthesis, antiproliferative activities and molecular docking studies A Faouzi, A Arnaud, A Bancet, C Barette, J Preto, CV Do, LP Jordheim, ... European Journal of Medicinal Chemistry 215, 113275, 2021 | 8 | 2021 |
Think big, start small: How nanomedicine could alleviate the burden of rare CNS diseases A Faouzi, VG Roullin Pharmaceuticals 14 (2), 109, 2021 | 4 | 2021 |
Design of first in class bitopic ligands targeting the sodium binding pocket in opioid receptors A Faouzi, S Zaidi, T Che, C Kormos, T Zhang, M Madasu, S Eans, ... The FASEB Journal 34 (S1), 1-1, 2020 | 2 | 2020 |
Syntheses and biological evaluations of combretastatine A-4 analogs and DYRK kinases inhibitors A Faouzi Université de Lyon, 2017 | | 2017 |
Synthèses et évaluations biologiques d’analogues de la combrétastatine A-4 et d’inhibiteurs de kinases DYRK A Faouzi Université de Lyon, 2017 | | 2017 |