Extracellular matrix assembly: a multiscale deconstruction JK Mouw, G Ou, VM Weaver Nature reviews Molecular cell biology 15 (12), 771-785, 2014 | 1539 | 2014 |
Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression JK Mouw, Y Yui, L Damiano, RO Bainer, JN Lakins, I Acerbi, G Ou, ... Nature medicine 20 (4), 360-367, 2014 | 436 | 2014 |
Force engages vinculin and promotes tumor progression by enhancing PI3K activation of phosphatidylinositol (3, 4, 5)-triphosphate MG Rubashkin, L Cassereau, R Bainer, CC DuFort, Y Yui, G Ou, ... Cancer research 74 (17), 4597-4611, 2014 | 221 | 2014 |
Integrin-mediated traction force enhances paxillin molecular associations and adhesion dynamics that increase the invasiveness of tumor cells into a three-dimensional … AH Mekhdjian, FB Kai, MG Rubashkin, LS Prahl, LM Przybyla, ... Molecular biology of the cell 28 (11), 1467-1488, 2017 | 136 | 2017 |
A 3D tension bioreactor platform to study the interplay between ECM stiffness and tumor phenotype L Cassereau, YA Miroshnikova, G Ou, J Lakins, VM Weaver Journal of biotechnology 193, 66-69, 2015 | 114 | 2015 |
Deconstructing signaling in three dimensions MG Rubashkin, G Ou, VM Weaver Biochemistry 53 (13), 2078-2090, 2014 | 72 | 2014 |
α5β1-Integrin promotes tension-dependent mammary epithelial cell invasion by engaging the fibronectin synergy site YA Miroshnikova, GI Rozenberg, L Cassereau, M Pickup, JK Mouw, G Ou, ... Molecular biology of the cell 28 (22), 2958-2977, 2017 | 62 | 2017 |
Visualizing mechanical modulation of nanoscale organization of cell-matrix adhesions G Ou, D Thakar, JC Tung, YA Miroshnikova, CC Dufort, E Gutierrez, ... Integrative Biology 8 (7), 795-804, 2016 | 17 | 2016 |
Tumor‐induced solid stress activates β‐catenin signaling to drive malignant behavior in normal, tumor‐adjacent cells G Ou, VM Weaver BioEssays 37 (12), 1293-1297, 2015 | 14 | 2015 |
ECM dimensionality tunes actin tension to modulate endoplasmic reticulum function and spheroid phenotypes of mammary epithelial cells FB Kai, G Ou, RW Tourdot, C Stashko, G Gaietta, MF Swift, N Volkmann, ... The EMBO Journal 41 (17), e109205, 2022 | 11 | 2022 |
Extracellular matrix dimensionality reduces cellular cortical tension to stimulate pro-survival signaling in mammary epithelial cells FB Kai, G Ou, A Long, W Guo, R Tourdot, R Radhakrishnan, C Chen, ... Cancer Research 79 (13_Supplement), 1028-1028, 2019 | | 2019 |
Single Grb2 recruitment dynamics are modulated by ECM mechanics. D Thakar, ST Low-Nam, F Kai, JN Lakins, G Ou, SD Hansen, JT Groves, ... MOLECULAR BIOLOGY OF THE CELL 29 (26), 2018 | | 2018 |
A Highlights from MBoC Selection: Integrin-mediated traction force enhances paxillin molecular associations and adhesion dynamics that increase the invasiveness of tumor cells … AH Mekhdjian, FB Kai, MG Rubashkin, LS Prahl, LM Przybyla, ... Molecular Biology of the Cell 28 (11), 1467, 2017 | | 2017 |
Extracellular matrix dimensionality reduces cellular cortical tension to stimulate Arf6/Rac/p38 pro-survival signaling in mammary epithelial cells. F Kai, G Ou, J Friedland, C Frantz, R Tourdot, W Guo, CS Chen, ... MOLECULAR BIOLOGY OF THE CELL 28, 2017 | | 2017 |
The Effect of Extracellular Biophysical Cues on Cellular Signal Processing G Ou University of California, San Francisco, 2016 | | 2016 |
A three-dimensional extracellular matrix enhances cell viability by increasing negative membrane curvature to stimulate Arf6/Rac/Pak activity. F Kai, G Ou, J Friedland, C Frantz, R Tourdot, W Guo, CS Chen, ... MOLECULAR BIOLOGY OF THE CELL 27, 2016 | | 2016 |
A three-dimensional extracellular matrix enhances cell viability by increasing negative membrane curvature to increase Arf6/Rac/Pak activity. FB Kai, G Ou, J Friedland, C Frantz, R Tourdot, W Guo, CS Chen, ... MOLECULAR BIOLOGY OF THE CELL 26, 2015 | | 2015 |
Extracellular mechanical cues drive vinculin mediated PI3-kinase signaling to enhance cell invasion in 3D. M Rubashkin, L Cassereau, R Bainer, C DuFort, Y Yui, G Ou, MJ Paszek, ... MOLECULAR BIOLOGY OF THE CELL 25, 2014 | | 2014 |
The Nanoscale Organization of Focal Adhesion Signaling Complexes can Reflect Changes in Cellular Contractility and Motility MG Rubashkin, C Dufort, P Oakes, M Paszek, G Ou, J Lakins, M Davidson, ... Biophysical Journal 106 (2), 575a-576a, 2014 | | 2014 |
Signaling in Context: Rac1 Activation Encodes for Increased Survival in 3D. G Ou, C Frantz, M Rubashkin, J Friedland, J Lakins, J Chernoff, LC Santy, ... MOLECULAR BIOLOGY OF THE CELL 23, 2012 | | 2012 |