| Design, synthesis, anticancer evaluation, and molecular modelling studies of novel tolmetin derivatives as potential VEGFR-2 inhibitors and apoptosis inducers AE Kassab, EM Gedawy, MIA Hamed, AS Doghish, RA Hassan Journal of enzyme inhibition and medicinal chemistry 36 (1), 922-939, 2021 | 88 | 2021 |
| Novel pyrazolo[3,4-d]pyrimidines: design, synthesis, anticancer activity, dual EGFR/ErbB2 receptor tyrosine kinases inhibitory activity, effects on cell cycle profile … M Maher, AE Kassab, AF Zaher, Z Mahmoud Journal of enzyme inhibition and medicinal chemistry 34 (1), 532-546, 2019 | 71 | 2019 |
| Synthesis and anticancer activity of novel 2-pyridyl hexahyrocyclooctathieno [2, 3-d] pyrimidine derivatives AE Kassab, EM Gedawy European Journal of Medicinal Chemistry 63, 224-230, 2013 | 71 | 2013 |
| Design, synthesis and biological evaluation of novel pyrazole sulfonamide derivatives as dual COX-2/5-LOX inhibitors EM Gedawy, AE Kassab, AM El Kerdawy European Journal of Medicinal Chemistry 189, 112066, 2020 | 69 | 2020 |
| Design and synthesis of thienopyrimidine urea derivatives with potential cytotoxic and pro-apoptotic activity against breast cancer cell line MCF-7 EF Abdelhaleem, MK Abdelhameid, AE Kassab, MM Kandeel European journal of medicinal chemistry 143, 1807-1825, 2018 | 65 | 2018 |
| Novel ciprofloxacin hybrids using biology oriented drug synthesis (BIODS) approach: Anticancer activity, effects on cell cycle profile, caspase-3 mediated apoptosis … AE Kassab, EM Gedawy European journal of medicinal chemistry 150, 403-418, 2018 | 64 | 2018 |
| Synthesis, anticancer activity and effects on cell cycle profile and apoptosis of novel thieno [2, 3-d] pyrimidine and thieno [3, 2-e] triazolo [4, 3-c] pyrimidine derivatives MM Kandeel, HM Refaat, AE Kassab, IG Shahin, TM Abdelghany European journal of medicinal chemistry 90, 620-632, 2015 | 59 | 2015 |
| Synthesis and biological evaluation of pyridazinone derivatives as selective COX-2 inhibitors and potential anti-inflammatory agents EM Ahmed, AE Kassab, AA El-Malah, MSA Hassan European Journal of Medicinal Chemistry 171, 25-37, 2019 | 52 | 2019 |
| Design, synthesis, and biological evaluation of thienopyrimidine derivatives as multifunctional agents against Alzheimer's disease KI Eissa, MM Kamel, LW Mohamed, AS Doghish, R Alnajjar, ... Drug Development Research 84 (5), 937-961, 2023 | 42 | 2023 |
| New pyridazine derivatives as selective COX-2 inhibitors and potential anti-inflammatory agents; design, synthesis and biological evaluation EM Ahmed, MSA Hassan, AA El-Malah, AE Kassab Bioorganic chemistry 95, 103497, 2020 | 34 | 2020 |
| Novel benzotriazole N-acylarylhydrazone hybrids: design, synthesis, anticancer activity, effects on cell cycle profile, caspase-3 mediated apoptosis and FAK inhibition AE Kassab, RA Hassan Bioorganic chemistry 80, 531-544, 2018 | 26 | 2018 |
| Evaluation of N-phenyl-2-aminothiazoles for treatment of multi-drug resistant and intracellular Staphylococcus aureus infections IG Shahin, NS Abutaleb, M Alhashimi, AE Kassab, KO Mohamed, ... European Journal of Medicinal Chemistry 202, 112497, 2020 | 25 | 2020 |
| Synthesis of effective anticancer thieno [2, 3-d] pyrimidine-4-ones and thieno [3, 2-e] triazolo [4, 3-c] pyrimidines MM Kandeel, AA Mounir, HM Refaat, AE Kassab Int J Pharm Pharm Sci 4 (3), 438-448, 2012 | 23 | 2012 |
| Synthesis and anticancer activity of novel tetrahydroquinoline and tetrahydropyrimidoquinoline derivatives EM Gedawy, AE Kassab, AA El-Malah Medicinal Chemistry Research 24, 3387-3397, 2015 | 18 | 2015 |
| Synthesis of Thieno[2,3-d]Pyrimidines, Thieno[2,3-d]Triazinones and Thieno[2,3-e]Diazepinones of Anticipated Anti-Cancer Activity MM Kandeel, AA Mounir, HM Refaat, AE Kassab Journal of Chemical Research 36 (2), 105-110, 2012 | 18 | 2012 |
| Synthesis, anticancer activity, effect on cell cycle profile, and apoptosis-inducing ability of novel hexahydrocyclooctathieno [2, 3-d] pyrimidine derivatives AE Kassab, EM Gedawy, AA El-Malah, TM Abdelghany, MS Abdel-Bakky Chemical and Pharmaceutical Bulletin 64 (5), 490-496, 2016 | 15 | 2016 |
| Novel tacrine analogs as potential cholinesterase inhibitors in Alzheimer's disease A El‐Malah, EM Gedawy, AE Kassab, RMA Salam Archiv der Pharmazie 347 (2), 96-103, 2014 | 15 | 2014 |
| Novel pyrazolopyrimidine urea derivatives: Synthesis, antiproliferative activity, VEGFR‐2 inhibition, and effects on the cell cycle profile AE Kassab, Y El‐Dash, EM Gedawy Archiv der Pharmazie 353 (4), 1900319, 2020 | 13 | 2020 |
| Synthesis of Potent Anticancer Thieno[2,3-d]Pyrimidine Derivatives MM Kandeel, AA Mounir, HM Refaat, AE Kassab Journal of Chemical Research 36 (5), 266-275, 2012 | 12 | 2012 |
| Design, synthesis, and biological evaluation of novel ciprofloxacin derivatives as potential anticancer agents targeting topoisomerase II enzyme HK Swedan, AE Kassab, EM Gedawy, SE Elmeligie Journal of Enzyme Inhibition and Medicinal Chemistry 38 (1), 118-137, 2023 | 11 | 2023 |
