IKKβ links inflammation and tumorigenesis in a mouse model of colitis-associated cancer FR Greten, L Eckmann, TF Greten, JM Park, ZW Li, LJ Egan, MF Kagnoff, ... Cell 118 (3), 285-296, 2004 | 3249 | 2004 |
Risk factors for opportunistic infections in patients with inflammatory bowel disease M Toruner, EV Loftus Jr, WS Harmsen, AR Zinsmeister, R Orenstein, ... Gastroenterology 134 (4), 929-936, 2008 | 1230 | 2008 |
The safety profile of infliximab in patients with Crohn’s disease: the Mayo clinic experience in 500 patients JF Colombel, EV Loftus Jr, WJ Tremaine, LJ Egan, WS Harmsen, ... Gastroenterology 126 (1), 19-31, 2004 | 1130 | 2004 |
The two faces of IKK and NF-κB inhibition: prevention of systemic inflammation but increased local injury following intestinal ischemia-reperfusion LW Chen, L Egan, ZW Li, FR Greten, MF Kagnoff, M Karin Nature medicine 9 (5), 575-581, 2003 | 637 | 2003 |
European evidence-based consensus: inflammatory bowel disease and malignancies V Annese, L Beaugerie, L Egan, L Biancone, C Bolling, C Brandts, ... Journal of Crohn's and Colitis 9 (11), 945-965, 2015 | 454 | 2015 |
Small-bowel imaging in Crohn's disease: a prospective, blinded, 4-way comparison trial CA Solem, EV Loftus Jr, JG Fletcher, TH Baron, CJ Gostout, BT Petersen, ... Gastrointestinal endoscopy 68 (2), 255-266, 2008 | 434 | 2008 |
Gastrointestinal radiation injury: symptoms, risk factors and mechanisms AK Shadad, FJ Sullivan, JD Martin, LJ Egan World journal of gastroenterology: WJG 19 (2), 185, 2013 | 279 | 2013 |
IκB-kinaseβ-dependent NF-κB activation provides radioprotection to the intestinal epithelium LJ Egan, L Eckmann, FR Greten, S Chae, ZW Li, GM Myhre, S Robine, ... Proceedings of the National Academy of Sciences 101 (8), 2452-2457, 2004 | 268 | 2004 |
Inhibition of interleukin-1-stimulated NF-κB RelA/p65 phosphorylation by mesalamine is accompanied by decreased transcriptional activity LJ Egan, DC Mays, CJ Huntoon, MP Bell, MG Pike, WJ Sandborn, ... Journal of Biological Chemistry 274 (37), 26448-26453, 1999 | 267 | 1999 |
Clinical outcome following treatment of refractory inflammatory and fistulizing Crohn's disease with intravenous cyclosporine LJ Egan, WJ Sandborn, WJ Tremaine The American journal of gastroenterology 93 (3), 442-448, 1998 | 226 | 1998 |
Celiac-associated lymphoma: a single institution experience of 30 cases in the combination chemotherapy era LJ Egan, SV Walsh, FM Stevens, CE Connolly, EL Egan, CF McCarthy Journal of clinical gastroenterology 21 (2), 123-129, 1995 | 213 | 1995 |
Inflammation, DNA methylation and colitis-associated cancer L Hartnett, LJ Egan Carcinogenesis 33 (4), 723-731, 2012 | 189 | 2012 |
Upregulation of DNA methyltransferase–mediated gene silencing, anchorage-independent growth, and migration of colon cancer cells by interleukin-6 E Foran, MM Garrity-Park, C Mureau, J Newell, TC Smyrk, PJ Limburg, ... Molecular Cancer Research 8 (4), 471-481, 2010 | 188 | 2010 |
Role of EHEC O157: H7 virulence factors in the activation of intestinal epithelial cell NF‐κB and MAP kinase pathways and the upregulated expression of interleukin 8 MC Berin, A Darfeuille‐Michaud, LJ Egan, Y Miyamoto, MF Kagnoff Cellular microbiology 4 (10), 635-648, 2002 | 186 | 2002 |
Gastroesophageal reflux disease in pregnancy RAR Ali, LJ Egan Best Practice & Research Clinical Gastroenterology 21 (5), 793-806, 2007 | 176 | 2007 |
Gastrointestinal radiation injury: prevention and treatment AK Shadad, FJ Sullivan, JD Martin, LJ Egan World journal of gastroenterology: WJG 19 (2), 199, 2013 | 169 | 2013 |
Selective inhibition of inflammatory gene expression in activated T lymphocytes: a mechanism of immune suppression by thiopurines CW Thomas, GM Myhre, R Tschumper, R Sreekumar, D Jelinek, ... Journal of Pharmacology and Experimental Therapeutics 312 (2), 537-545, 2005 | 158 | 2005 |
Gene-set analysis is severely biased when applied to genome-wide methylation data P Geeleher, L Hartnett, LJ Egan, A Golden, RA Raja Ali, C Seoighe Bioinformatics 29 (15), 1851-1857, 2013 | 157 | 2013 |
Nitric oxide promotes endothelial cell survival signaling through S-nitrosylation and activation of dynamin-2 N Kang-Decker, S Cao, S Chatterjee, J Yao, LJ Egan, D Semela, ... Journal of cell science 120 (3), 492-501, 2007 | 145 | 2007 |
Optimising monitoring in the management of Crohn's disease: a physician's perspective P Papay, A Ignjatovic, K Karmiris, H Amarante, P Miheller, B Feagan, ... Journal of Crohn's and Colitis 7 (8), 653-669, 2013 | 138 | 2013 |