Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility International Multiple Sclerosis Genetics Consortium*†, ANZgene, ... Science 365 (6460), eaav7188, 2019 | 1028 | 2019 |
IL-9 induces differentiation of TH17 cells and enhances function of FoxP3+ natural regulatory T cells W Elyaman, EM Bradshaw, C Uyttenhove, V Dardalhon, A Awasthi, ... Proceedings of the National Academy of Sciences 106 (31), 12885-12890, 2009 | 874 | 2009 |
CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology EM Bradshaw, LB Chibnik, BT Keenan, L Ottoboni, T Raj, A Tang, ... Nature neuroscience 16 (7), 848-850, 2013 | 623 | 2013 |
Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer’s disease M Olah, V Menon, N Habib, MF Taga, Y Ma, CJ Yung, M Cimpean, ... Nature communications 11 (1), 6129, 2020 | 541 | 2020 |
A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer’s disease S Mostafavi, C Gaiteri, SE Sullivan, CC White, S Tasaki, J Xu, M Taga, ... Nature neuroscience 21 (6), 811-819, 2018 | 441 | 2018 |
A transcriptomic atlas of aged human microglia M Olah, E Patrick, AC Villani, J Xu, CC White, KJ Ryan, P Piehowski, ... Nature communications 9 (1), 539, 2018 | 437 | 2018 |
Polyfunctional responses by human T cells result from sequential release of cytokines Q Han, N Bagheri, EM Bradshaw, DA Hafler, DA Lauffenburger, JC Love Proceedings of the National Academy of Sciences 109 (5), 1607-1612, 2012 | 387 | 2012 |
Monocytes from patients with type 1 diabetes spontaneously secrete proinflammatory cytokines inducing Th17 cells EM Bradshaw, K Raddassi, W Elyaman, T Orban, PA Gottlieb, SC Kent, ... The Journal of Immunology 183 (7), 4432-4439, 2009 | 354 | 2009 |
Multidimensional analysis of the frequencies and rates of cytokine secretion from single cells by quantitative microengraving Q Han, EM Bradshaw, B Nilsson, DA Hafler, JC Love Lab on a Chip 10 (11), 1391-1400, 2010 | 233 | 2010 |
TGF-β Induces IL-9 Production from human Th17 Cells G Beriou, EM Bradshaw, E Lozano, CM Costantino, WD Hastings, ... The Journal of Immunology 185 (1), 46-54, 2010 | 225 | 2010 |
Plasma cells in muscle in inclusion body myositis and polymyositis SA Greenberg, EM Bradshaw, JL Pinkus, GS Pinkus, T Burleson, B Due, ... Neurology 65 (11), 1782-1787, 2005 | 216 | 2005 |
Notch receptors and Smad3 signaling cooperate in the induction of interleukin-9-producing T cells W Elyaman, R Bassil, EM Bradshaw, W Orent, Y Lahoud, B Zhu, F Radtke, ... Immunity 36 (4), 623-634, 2012 | 201 | 2012 |
A local antigen-driven humoral response is present in the inflammatory myopathies EM Bradshaw, A Orihuela, SL McArdel, M Salajegheh, AA Amato, ... The Journal of Immunology 178 (1), 547-556, 2007 | 177 | 2007 |
Increased expression of the immune modulatory molecule PD-L1 (CD274) in anaplastic meningioma Z Du, M Abedalthagafi, AA Aizer, AR McHenry, HH Sun, MA Bray, ... Oncotarget 6 (7), 4704, 2014 | 170 | 2014 |
CD33 modulates TREM2: convergence of Alzheimer loci G Chan, CC White, PA Winn, M Cimpean, JM Replogle, LR Glick, ... Nature neuroscience 18 (11), 1556-1558, 2015 | 169 | 2015 |
Unusual 1H NMR chemical shifts support (His) Cɛ1—H⋅⋅⋅O⩵C H-bond: Proposal for reaction-driven ring flip mechanism in serine protease catalysis EL Ash, JL Sudmeier, RM Day, M Vincent, EV Torchilin, KC Haddad, ... Proceedings of the National Academy of Sciences 97 (19), 10371-10376, 2000 | 169 | 2000 |
Neuropathological correlates and genetic architecture of microglial activation in elderly human brain D Felsky, T Roostaei, K Nho, SL Risacher, EM Bradshaw, V Petyuk, ... Nature communications 10 (1), 409, 2019 | 164 | 2019 |
CD33: increased inclusion of exon 2 implicates the Ig V-set domain in Alzheimer's disease susceptibility T Raj, KJ Ryan, JM Replogle, LB Chibnik, L Rosenkrantz, A Tang, ... Human molecular genetics 23 (10), 2729-2736, 2014 | 161 | 2014 |
A human microglia-like cellular model for assessing the effects of neurodegenerative disease gene variants KJ Ryan, CC White, K Patel, J Xu, M Olah, JM Replogle, M Frangieh, ... Science translational medicine 9 (421), eaai7635, 2017 | 134 | 2017 |
JAGGED1 and delta1 differentially regulate the outcome of experimental autoimmune encephalomyelitis W Elyaman, EM Bradshaw, Y Wang, M Oukka, P Kivisäkk, S Chiba, ... The Journal of Immunology 179 (9), 5990-5998, 2007 | 125 | 2007 |