The contribution of de novo coding mutations to autism spectrum disorder I Iossifov, BJ O’roak, SJ Sanders, M Ronemus, N Krumm, D Levy, ... Nature 515 (7526), 216-221, 2014 | 2645 | 2014 |
De novo gene disruptions in children on the autistic spectrum I Iossifov, M Ronemus, D Levy, Z Wang, I Hakker, J Rosenbaum, ... Neuron 74 (2), 285-299, 2012 | 1676 | 2012 |
Discovery of cancer drug targets by CRISPR-Cas9 screening of protein domains J Shi, E Wang, JP Milazzo, Z Wang, JB Kinney, CR Vakoc Nature biotechnology 33 (6), 661-667, 2015 | 784 | 2015 |
Accurate de novo and transmitted indel detection in exome-capture data using microassembly G Narzisi, JA O'rawe, I Iossifov, H Fang, Y Lee, Z Wang, Y Wu, GJ Lyon, ... Nature methods 11 (10), 1033-1036, 2014 | 240 | 2014 |
Varietal counting of nucleic acids for obtaining genomic copy number information J Hicks, N Navin, J Troge, Z Wang, M Wigler US Patent 9,404,156, 2016 | 195 | 2016 |
Chromosomal instability accelerates the evolution of resistance to anti-cancer therapies DA Lukow, EL Sausville, P Suri, NK Chunduri, A Wieland, J Leu, JC Smith, ... Developmental cell 56 (17), 2427-2439. e4, 2021 | 131 | 2021 |
Indel variant analysis of short-read sequencing data with Scalpel H Fang, EA Bergmann, K Arora, V Vacic, MC Zody, I Iossifov, JA O'rawe, ... Nature protocols 11 (12), 2529-2548, 2016 | 118 | 2016 |
Autism risk in offspring can be assessed through quantification of male sperm mosaicism MW Breuss, D Antaki, RD George, M Kleiber, KN James, LL Ball, O Hong, ... Nature Medicine 26 (1), 143-150, 2020 | 92 | 2020 |
Single-chromosomal gains can function as metastasis suppressors and promoters in colon cancer A Vasudevan, PS Baruah, JC Smith, Z Wang, NM Sayles, P Andrews, ... Developmental Cell 52 (4), 413-428. e6, 2020 | 87 | 2020 |
A functional polymorphism within the MRP1 gene locus identified through its genomic signature of positive selection Z Wang, B Wang, K Tang, EJD Lee, SS Chong, CGL Lee Human molecular genetics 14 (14), 2075-2087, 2005 | 70 | 2005 |
Nucleotide sequence analyses of the MRP 1 gene in four populations suggest negative selection on its coding region Z Wang, PH Sew, H Ambrose, S Ryan, SS Chong, EJD Lee, CGL Lee BMC genomics 7, 1-18, 2006 | 39 | 2006 |
Predicting potentially functional SNPs in drug-response genes GSY Pang, J Wang, Z Wang, CGL Lee Pharmacogenomics 10 (4), 639-653, 2009 | 31 | 2009 |
Rates of contributory de novo mutation in high and low-risk autism families S Yoon, A Munoz, B Yamrom, Y Lee, P Andrews, S Marks, Z Wang, ... Communications biology 4 (1), 1026, 2021 | 28 | 2021 |
Signatures of recent positive selection at the ATP-binding cassette drug transporter superfamily gene loci Z Wang, J Wang, E Tantoso, B Wang, AYP Tai, LLPJ Ooi, SS Chong, ... Human molecular genetics 16 (11), 1367-1380, 2007 | 27 | 2007 |
SMASH, a fragmentation and sequencing method for genomic copy number analysis Z Wang, P Andrews, J Kendall, B Ma, I Hakker, L Rodgers, M Ronemus, ... Genome research 26 (6), 844-851, 2016 | 22 | 2016 |
The G allele of SNP E1/A118G at the µ-opioid receptor gene locus shows genomic evidence of recent positive selection GSY Pang, J Wang, Z Wang, C Goh, CGL Lee Pharmacogenomics 10 (7), 1101-1109, 2009 | 21 | 2009 |
DNA copy number variations in children with vesicoureteral reflux and urinary tract infections D Liang, KM McHugh, PD Brophy, N Shaikh, JR Manak, P Andrews, ... PLoS One 14 (8), e0220617, 2019 | 16 | 2019 |
Fetal polymorphisms at the ABCB1-transporter gene locus are associated with susceptibility to non-syndromic oral cleft malformations A Omoumi, Z Wang, V Yeow, YH Wu-Chou, PK Chen, I Ruczinski, ... European Journal of Human Genetics 21 (12), 1436-1441, 2013 | 14 | 2013 |
Copolymerization of single-cell nucleic acids into balls of acrylamide gel S Li, J Kendall, S Park, Z Wang, J Alexander, A Moffitt, N Ranade, ... Genome Research 30 (1), 49-61, 2020 | 11 | 2020 |
Mining potential functionally significant polymorphisms at the ATP-binding-cassette transporter genes Z Wang, J Wang, SS Chong, CGL Lee Current Pharmacogenomics and Personalized Medicine (Formerly Current …, 2009 | 11 | 2009 |