AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis T Okuda, J Van Deursen, SW Hiebert, G Grosveld, JR Downing Cell 84 (2), 321-330, 1996 | 2310 | 1996 |
The E2F transcription factor is a cellular target for the RB protein SP Chellappan, S Hiebert, M Mudryj, JM Horowitz, JR Nevins Cell 65 (6), 1053-1061, 1991 | 1934 | 1991 |
Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4. JY Kato, H Matsushime, SW Hiebert, ME Ewen, CJ Sherr Genes & development 7 (3), 331-342, 1993 | 1705 | 1993 |
Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia. TR Golub, GF Barker, SK Bohlander, SW Hiebert, DC Ward, P Bray-Ward, ... Proceedings of the National Academy of Sciences 92 (11), 4917-4921, 1995 | 953 | 1995 |
The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F. SW Hiebert, SP Chellappan, JM Horowitz, JR Nevins Genes & development 6 (2), 177-185, 1992 | 777 | 1992 |
Identification of AML-1 and the (8; 21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: the runt homology domain is required for DNA binding and … S Meyers, JR Downing, SW Hiebert Molecular and cellular biology, 1993 | 617 | 1993 |
ETO, a target of t (8; 21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors B Lutterbach, JJ Westendorf, B Linggi, A Patten, M Moniwa, JR Davie, ... Molecular and cellular biology 18 (12), 7176-7184, 1998 | 569 | 1998 |
CCAAT enhancer-binding protein (C/EBP) and AML1 (CBFα2) synergistically activate the macrophage colony-stimulating factor receptor promoter DE Zhang, CJ Hetherington, S Meyers, KL Rhoades, CJ Larson, ... Molecular and cellular biology, 1996 | 494 | 1996 |
The t (8; 21) fusion protein interferes with AML-1B-dependent transcriptional activation S Meyers, N Lenny, SW Hiebert Molecular and cellular biology 15 (4), 1974-1982, 1995 | 494 | 1995 |
ETO, a target of t (8; 21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain JM Amann, J Nip, DK Strom, B Lutterbach, H Harada, N Lenny, ... Molecular and cellular biology 21 (19), 6470-6483, 2001 | 482 | 2001 |
Analysis of protein dynamics at active, stalled, and collapsed replication forks BM Sirbu, FB Couch, JT Feigerle, S Bhaskara, SW Hiebert, D Cortez Genes & development 25 (12), 1320-1327, 2011 | 478 | 2011 |
Deletion of histone deacetylase 3 reveals critical roles in S phase progression and DNA damage control S Bhaskara, BJ Chyla, JM Amann, SK Knutson, D Cortez, ZW Sun, ... Molecular cell 30 (1), 61-72, 2008 | 445 | 2008 |
Cell cycle regulation of the E2F transcription factor involves an interaction with cyclin A M Mudryj, SH Devoto, SW Hiebert, T Hunter, J Pines, JR Nevins Cell 65 (7), 1243-1253, 1991 | 441 | 1991 |
E1A-dependent trans-activation of the human MYC promoter is mediated by the E2F factor. SW Hiebert, M Lipp, JR Nevins Proceedings of the National Academy of Sciences 86 (10), 3594-3598, 1989 | 403 | 1989 |
Hdac3 is essential for the maintenance of chromatin structure and genome stability S Bhaskara, SK Knutson, G Jiang, MB Chandrasekharan, AJ Wilson, ... Cancer cell 18 (5), 436-447, 2010 | 400 | 2010 |
PEBP2/CBF, the murine homolog of the human myeloid AML1 and PEBP2β/CBFβ proto-oncoproteins, regulates the murine myeloperoxidase and neutrophil elastase genes in immature … I Nuchprayoon, S Meyers, LM Scott, J Suzow, S Hiebert, AD Friedman Molecular and cellular biology 14 (8), 5558-5568, 1994 | 392 | 1994 |
Translocation products in acute myeloid leukemia activate the Wnt signaling pathway in hematopoietic cells C Müller-Tidow, B Steffen, T Cauvet, L Tickenbrock, P Ji, S Diederichs, ... Molecular and cellular biology 24 (7), 2890-2904, 2004 | 387 | 2004 |
Requirement for the histone deacetylase Hdac3 for the inflammatory gene expression program in macrophages X Chen, I Barozzi, A Termanini, E Prosperini, A Recchiuti, J Dalli, ... Proceedings of the National Academy of Sciences 109 (42), E2865-E2874, 2012 | 379 | 2012 |
The t (12; 21) translocation converts AML-1B from an activator to a repressor of transcription SW Hiebert, W Sun, JN Davis, T Golub, S Shurtleff, A Buijs, JR Downing, ... Molecular and cellular biology, 1996 | 353 | 1996 |
The t (8; 21) fusion product, AML-1–ETO, associates with C/EBP-α, inhibits C/EBP-α-dependent transcription, and blocks granulocytic differentiation JJ Westendorf, CM Yamamoto, N Lenny, JR Downing, ME Selsted, ... Molecular and cellular biology, 1998 | 324 | 1998 |