Current development of siRNA bioconjugates: from research to the clinic IV Chernikov, VV Vlassov, EL Chernolovskaya Frontiers in pharmacology 10, 444, 2019 | 206 | 2019 |
Carrier-free cellular uptake and the gene-silencing activity of the lipophilic siRNAs is strongly affected by the length of the linker between siRNA and lipophilic group NS Petrova, IV Chernikov, MI Meschaninova, IIS Dovydenko, ... Nucleic acids research 40 (5), 2330-2344, 2012 | 101 | 2012 |
Cholesterol-containing nuclease-resistant siRNA accumulates in tumors in a carrier-free mode and silences MDR1 gene IV Chernikov, DV Gladkikh, MI Meschaninova, AG Ven'yaminova, ... Molecular Therapy-Nucleic Acids 6, 209-220, 2017 | 77 | 2017 |
Autocrine-based selection of ligands for personalized CAR-T therapy of lymphoma AV Stepanov, OV Markov, IV Chernikov, DV Gladkikh, H Zhang, T Jones, ... Science advances 4 (11), eaau4580, 2018 | 30 | 2018 |
Antisense oligonucleotide gapmers containing phosphoryl guanidine groups reverse MDR1-mediated multiple drug resistance of tumor cells MS Kupryushkin, AV Filatov, NL Mironova, OA Patutina, IV Chernikov, ... Molecular Therapy-Nucleic Acids 27, 211-226, 2022 | 18 | 2022 |
Transport Oligonucleotides—A Novel System for Intracellular Delivery of Antisense Therapeutics OV Markov, AV Filatov, MS Kupryushkin, IV Chernikov, OA Patutina, ... Molecules 25 (16), 3663, 2020 | 15 | 2020 |
Folate-equipped cationic liposomes deliver anti-mdr1-sirna to the tumor and increase the efficiency of chemotherapy DV Gladkikh, AV Sen′ kova, IV Chernikov, TO Kabilova, NA Popova, ... Pharmaceutics 13 (8), 1252, 2021 | 14 | 2021 |
Structural modifications of siRNA improve its performance in vivo IV Chernikov, UA Ponomareva, EL Chernolovskaya International Journal of Molecular Sciences 24 (2), 956, 2023 | 13 | 2023 |
Fluorophore Labeling Affects the Cellular Accumulation and Gene Silencing Activity of Cholesterol-Modified siRNAs In Vitro IV Chernikov, DV Gladkikh, MI Meschaninova, UA Karelina, ... Nucleic acid therapeutics 29 (1), 33-43, 2019 | 12 | 2019 |
Trimeric small interfering RNAs and their cholesterol-containing conjugates exhibit improved accumulation in tumors, but dramatically reduced silencing activity IV Chernikov, DV Gladkikh, UA Karelina, MI Meschaninova, ... Molecules 25 (8), 1877, 2020 | 9 | 2020 |
Nuclease‐resistant 63‐bp trimeric si RNA s simultaneously silence three different genes in tumor cells OV Gvozdeva, DV Gladkih, IV Chernikov, MI Meschaninova, ... FEBS letters 592 (1), 122-129, 2018 | 8 | 2018 |
siRNA-Mediated Timp1 Silencing Inhibited the Inflammatory Phenotype during Acute Lung Injury IV Chernikov, YY Staroseletz, IS Tatarnikova, AV Sen’kova, IA Savin, ... International Journal of Molecular Sciences 24 (2), 1641, 2023 | 7 | 2023 |
1-Hydroxyanthraquinones Containing Aryl Substituents as Potent and Selective Anticancer Agents NS Sirazhetdinova, VA Savelyev, TS Frolova, DS Baev, LS Klimenko, ... Molecules 25 (11), 2547, 2020 | 6 | 2020 |
Soloxolone methyl reduces the stimulatory effect of leptin on the aggressive phenotype of murine Neuro2a neuroblastoma cells via the MAPK/ERK1/2 pathway KV Odarenko, OV Salomatina, IV Chernikov, NF Salakhutdinov, ... Pharmaceuticals 16 (10), 1369, 2023 | 4 | 2023 |
Preparation, Determination of Activity, and Biodistribution of Cholesterol-Containing Nuclease-Resistant siRNAs In Vivo IV Chernikov, MI Meschaninova, EL Chernolovskaya RNA Interference and CRISPR Technologies: Technical Advances and New …, 2020 | 4 | 2020 |
Cholesterol-Conjugated siRNA Accumulates in the Different Hematopoietic and Lymphoid Cells. IV Chernikov, MI Meschaninova, AG Venyaminova, MA Zenkova, ... Journal of Hematology and Oncology Research 2 (2), 13-19, 2016 | 3 | 2016 |
Symmetric lipophilic polyamines exhibiting antitumor activity KA Perevoshchikova, EA Eshtukova-Shcheglova, OV Markov, AV Markov, ... Bioorganic & Medicinal Chemistry 76, 117089, 2022 | 2 | 2022 |
Uncharged Gemini-Amphiphiles as Components of Cationic Liposomes for Delivery of Nucleic Acids EV Shmendel, SA Bakhareva, DM Makarova, IV Chernikov, NG Morozova, ... Russian Journal of Bioorganic Chemistry 46, 1250-1260, 2020 | 2 | 2020 |
Investigation of the Internalization of Fluorescently Labeled Lipophilic siRNA into Cultured Tumor Cells IV Chernikov, UA Karelina, MI Meschaninova, AG Ven’yaminova, ... Russian Journal of Bioorganic Chemistry 45, 766-773, 2019 | 2 | 2019 |
Cholesterol-Modified Anti-Il6 siRNA Reduces the Severity of Acute Lung Injury in Mice IV Chernikov, IK Bachkova, AV Sen’kova, MI Meschaninova, IA Savin, ... Cells 13 (9), 767, 2024 | 1 | 2024 |