An engineered affibody molecule with pH-dependent binding to FcRn mediates extended circulatory half-life of a fusion protein J Seijsing, M Lindborg, I Höidén-Guthenberg, H Bönisch, E Gunneriusson, ... | 58* | |
Improved biodistribution and extended serum half-life of a bacteriophage endolysin by albumin binding domain fusion J Seijsing, AM Sobieraj, N Keller, Y Shen, AS Zinkernagel, MJ Loessner, ... Frontiers in microbiology 9, 2927, 2018 | 49 | 2018 |
In vivo depletion of serum IgG by an affibody molecule binding the neonatal Fc receptor J Seijsing, S Yu, FY Frejd, I Höiden-Guthenberg, T Gräslund Scientific Reports 8 (1), 5141, 2018 | 42 | 2018 |
Bioactive Silk Coatings Reduce the Adhesion of Staphylococcus aureus while Supporting Growth of Osteoblast-like Cells L Nileback, M Widhe, J Seijsing, H Bysell, PK Sharma, M Hedhammar ACS Applied Materials & Interfaces 11 (28), 24999-25007, 2019 | 39 | 2019 |
Target-specific cytotoxic effects on HER2-expressing cells by the tripartite fusion toxin ZHER2: 2891-ABD-PE38X8, including a targeting affibody molecule and a half-life … H Liu, J Seijsing, FY Frejd, V Tolmachev, T Gräslund International Journal of Oncology 47 (2), 601-609, 2015 | 29 | 2015 |
Recombinant spider silk coatings functionalized with enzymes targeting bacteria and biofilms F Seijsing, L Nilebäck, O Öhman, R Pasupuleti, C Ståhl, J Seijsing, ... MicrobiologyOpen 9 (4), e993, 2020 | 21 | 2020 |
Lysis of staphylococcal cells by modular lysin domains linked via a non-covalent barnase-barstar interaction bridge LC Hjelm, J Nilvebrant, PÅ Nygren, AS Nilsson, J Seijsing Frontiers in microbiology 10, 558, 2019 | 10 | 2019 |
Robust expression of the human neonatal Fc receptor in a truncated soluble form and as a full-length membrane-bound protein in fusion with eGFP J Seijsing, M Lindborg, J Löfblom, M Uhlén, T Gräslund PLoS One 8 (11), e81350, 2013 | 7 | 2013 |
Polypeptides C Ekblad, E Gunneriusson, M Lindborg, L Abrahmsen, J Löblom, ... US Patent 9,975,943, 2018 | 3 | 2018 |
New polypeptides L Abrahmsén, C Ekblad, E Gunneriusson, T GRÄSLUND, J SEIJSING, ... | 1 | 2016 |
Improved bacteria-phagocyte interaction by means of a fusion protein binding Staphylococcus peptidoglycan and Immunoglobulin G F Seijsing, T de Neergaard, N Pontus, J Seijsing, A Nilsson | | 2021 |
Structure prediction of endolysin SU57e F Seijsing, J Seijsing, A Nilsson | | 2021 |
Polypeptides C Ekblad, E Gunneriusson, M Lindborg, L Abrahmsen, J Löfblom, ... US Patent App. 16/743,344, 2020 | | 2020 |
6. Manuscript I: Improved biodistribution and extended serum half-life of a bacteriophage endolysin by albumin binding domain fusion J Seijsing, AM Sobieraj, N Keller, Y Shen, AS Zinkernagel, MJ Loessner, ... Engineering of bacteriophage endolysins for treatment of systemic drug …, 2020 | | 2020 |
Polypeptides C Ekblad, E Gunneriusson, M Lindborg, L Abrahmsen, J Löfblom, ... US Patent 10,562,955, 2020 | | 2020 |
Neonatal Fc Receptor Binding Dimer and Methods of Use L Abrahmsén, C Ekblad, E Gunneriusson, T Gräslund, J Seijsing, ... US Patent App. 16/377,722, 2019 | | 2019 |
Nye polypeptider L Abrahmsén, C Ekblad, E Gunneriusson, T Gräslund, J Löfblom, ... | | 2019 |
New polypeptides Abrahmsen, Lars, Ekblad, Caroline, Gunneriusson, Elin, ... AU Patent AU2,015,316,795, 2017 | | 2017 |
Rational and Combinatorial Engineering of Affinity Proteins Towards Therapeutical Applications J Seijsing KTH Royal Institute of Technology, 2014 | | 2014 |
Up-regulation of endogenous GAD67 expression in vivo using designed zinc finger-based transcription factors E Elgstrand Wettergren, J Seijsing, M Sest, L Quintino, T Gräslund, ... | | 2014 |