| Design of a novel globular protein fold with atomic-level accuracy B Kuhlman, G Dantas, GC Ireton, G Varani, BL Stoddard, D Baker science 302 (5649), 1364-1368, 2003 | 2064 | 2003 |
| ROSETTA3: an object-oriented software suite for the simulation and design of macromolecules A Leaver-Fay, M Tyka, SM Lewis, OF Lange, J Thompson, R Jacak, ... Methods in enzymology 487, 545-574, 2011 | 1969 | 2011 |
| Protein–protein docking with simultaneous optimization of rigid-body displacement and side-chain conformations JJ Gray, S Moughon, C Wang, O Schueler-Furman, B Kuhlman, CA Rohl, ... Journal of molecular biology 331 (1), 281-299, 2003 | 1329 | 2003 |
| The Rosetta all-atom energy function for macromolecular modeling and design RF Alford, A Leaver-Fay, JR Jeliazkov, MJ O’Meara, FP DiMaio, H Park, ... Journal of chemical theory and computation 13 (6), 3031-3048, 2017 | 1304 | 2017 |
| A genetically encoded photoactivatable Rac controls the motility of living cells YI Wu, D Frey, OI Lungu, A Jaehrig, I Schlichting, B Kuhlman, KM Hahn Nature 461 (7260), 104-108, 2009 | 1265 | 2009 |
| Native protein sequences are close to optimal for their structures B Kuhlman, D Baker Proceedings of the National Academy of Sciences 97 (19), 10383-10388, 2000 | 1028 | 2000 |
| Advances in protein structure prediction and design B Kuhlman, P Bradley Nature reviews molecular cell biology 20 (11), 681-697, 2019 | 719 | 2019 |
| Labelling and optical erasure of synaptic memory traces in the motor cortex A Hayashi-Takagi, S Yagishita, M Nakamura, F Shirai, YI Wu, ... Nature 525 (7569), 333-338, 2015 | 688 | 2015 |
| Engineering an improved light-induced dimer (iLID) for controlling the localization and activity of signaling proteins G Guntas, RA Hallett, SP Zimmerman, T Williams, H Yumerefendi, ... Proceedings of the National Academy of Sciences 112 (1), 112-117, 2015 | 623 | 2015 |
| Macromolecular modeling and design in Rosetta: recent methods and frameworks JK Leman, BD Weitzner, SM Lewis, J Adolf-Bryfogle, N Alam, RF Alford, ... Nature methods 17 (7), 665-680, 2020 | 609 | 2020 |
| Serverification of molecular modeling applications: the Rosetta Online Server that Includes Everyone (ROSIE) S Lyskov, FC Chou, SO Conchuir, BS Der, K Drew, D Kuroda, J Xu, ... PloS one 8 (5), e63906, 2013 | 407 | 2013 |
| A large scale test of computational protein design: folding and stability of nine completely redesigned globular proteins G Dantas, B Kuhlman, D Callender, M Wong, D Baker Journal of molecular biology 332 (2), 449-460, 2003 | 402 | 2003 |
| LOVTRAP: an optogenetic system for photoinduced protein dissociation H Wang, M Vilela, A Winkler, M Tarnawski, I Schlichting, H Yumerefendi, ... Nature methods 13 (9), 755-758, 2016 | 325 | 2016 |
| Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface SM Lewis, X Wu, A Pustilnik, A Sereno, F Huang, HL Rick, G Guntas, ... Nature biotechnology 32 (2), 191-198, 2014 | 291 | 2014 |
| Computer-based redesign of a protein folding pathway S Nauli, B Kuhlman, D Baker Nature structural biology 8 (7), 602-605, 2001 | 280 | 2001 |
| RosettaDesign server for protein design Y Liu, B Kuhlman Nucleic acids research 34 (suppl_2), W235-W238, 2006 | 266 | 2006 |
| Combined covalent-electrostatic model of hydrogen bonding improves structure prediction with Rosetta MJ O’Meara, A Leaver-Fay, MD Tyka, A Stein, K Houlihan, F DiMaio, ... Journal of chemical theory and computation 11 (2), 609-622, 2015 | 248 | 2015 |
| Designing photoswitchable peptides using the AsLOV2 domain OI Lungu, RA Hallett, EJ Choi, MJ Aiken, KM Hahn, B Kuhlman Chemistry & biology 19 (4), 507-517, 2012 | 247 | 2012 |
| Scientific benchmarks for guiding macromolecular energy function improvement A Leaver-Fay, MJ O'meara, M Tyka, R Jacak, Y Song, EH Kellogg, ... Methods in enzymology 523, 109-143, 2013 | 243 | 2013 |
| E2 conjugating enzymes must disengage from their E1 enzymes before E3-dependent ubiquitin and ubiquitin-like transfer ZM Eletr, DT Huang, DM Duda, BA Schulman, B Kuhlman Nature structural & molecular biology 12 (10), 933-934, 2005 | 222 | 2005 |
