Structural and functional insights into enzymes of the vitamin K cycle JK Tie, DW Stafford Journal of Thrombosis and Haemostasis 14 (2), 236-247, 2016 | 157 | 2016 |
Functional study of the vitamin K cycle in mammalian cells JK Tie, DY Jin, DL Straight, DW Stafford Blood, The Journal of the American Society of Hematology 117 (10), 2967-2974, 2011 | 127 | 2011 |
Membrane topology mapping of vitamin K epoxide reductase by in vitro translation/cotranslocation JK Tie, C Nicchitta, G Von Heijne, DW Stafford Journal of Biological Chemistry 280 (16), 16410-16416, 2005 | 124 | 2005 |
The conversion of vitamin K epoxide to vitamin K quinone and vitamin K quinone to vitamin K hydroquinone uses the same active site cysteines DY Jin, JK Tie, DW Stafford Biochemistry 46 (24), 7279-7283, 2007 | 102 | 2007 |
Structure and function of vitamin K epoxide reductase JK Tie, DW Stafford Vitamins & Hormones 78, 103-130, 2008 | 100 | 2008 |
A topological study of the human γ-glutamyl carboxylase J Tie, SM Wu, D Jin, CV Nicchitta, DW Stafford Blood, The Journal of the American Society of Hematology 96 (3), 973-978, 2000 | 74 | 2000 |
Characterization of vitamin K–dependent carboxylase mutations that cause bleeding and nonbleeding disorders JK Tie, JDA Carneiro, DY Jin, CD Martinhago, C Vermeer, DW Stafford Blood, The Journal of the American Society of Hematology 127 (15), 1847-1855, 2016 | 62 | 2016 |
Evaluation of warfarin resistance using transcription activator‐like effector nucleases‐mediated vitamin K epoxide reductase knockout HEK293 cells JK Tie, DY Jin, K Tie, DW Stafford Journal of Thrombosis and Haemostasis 11 (8), 1556-1564, 2013 | 61 | 2013 |
Warfarin and vitamin K epoxide reductase: a molecular accounting for observed inhibition S Wu, X Chen, DY Jin, DW Stafford, LG Pedersen, JK Tie Blood, The Journal of the American Society of Hematology 132 (6), 647-657, 2018 | 57 | 2018 |
Human Vitamin K Epoxide Reductase and Its Bacterial Homologue Have Different Membrane Topologies and Reaction Mechanisms*♦ JK Tie, DY Jin, DW Stafford Journal of Biological Chemistry 287 (41), 33945-33955, 2012 | 56 | 2012 |
Chemiluminescence investigation of the interaction of metalloporphyrins with nucleic acids YX Ci, YG Zheng, JK Tie, WB Chang Analytica chimica acta 282 (3), 695-701, 1993 | 54 | 1993 |
Determination of disulfide bond assignment of human vitamin K-dependent γ-glutamyl carboxylase by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry JK Tie, VP Mutucumarana, DL Straight, KL Carrick, RM Pope, DW Stafford Journal of Biological Chemistry 278 (46), 45468-45475, 2003 | 42 | 2003 |
A genome-wide CRISPR-Cas9 knockout screen identifies FSP1 as the warfarin-resistant vitamin K reductase DY Jin, X Chen, Y Liu, CM Williams, LC Pedersen, DW Stafford, JK Tie Nature Communications 14 (1), 828, 2023 | 39 | 2023 |
Functional study of the vitamin K cycle enzymes in live cells JK Tie, DW Stafford Methods in enzymology 584, 349-394, 2017 | 38 | 2017 |
The putative vitamin K-dependent γ-glutamyl carboxylase internal propeptide appears to be the propeptide binding site PJ Lin, DY Jin, JK Tie, SR Presnell, DL Straight, DW Stafford Journal of Biological Chemistry 277 (32), 28584-28591, 2002 | 37 | 2002 |
Flow injection and liquid chromatographic postcolumn detection of amino acids by mimetic peroxidase-catalysed chemiluminescence reaction YX Ci, JK Tie, QW Wang, WB Chang Analytica chimica acta 269 (1), 109-114, 1992 | 30 | 1992 |
Evaluation of oral anticoagulants with vitamin K epoxide reductase in its native milieu X Chen, DY Jin, DW Stafford, JK Tie Blood, The Journal of the American Society of Hematology 132 (18), 1974-1984, 2018 | 29 | 2018 |
Conserved loop cysteines of vitamin K epoxide reductase complex subunit 1-like 1 (VKORC1L1) are involved in its active site regeneration JK Tie, DY Jin, DW Stafford Journal of Biological Chemistry 289 (13), 9396-9407, 2014 | 29 | 2014 |
Cyclooctatetraene: a bioactive cubane paradigm complement H Xing, SD Houston, X Chen, S Ghassabian, T Fahrenhorst‐Jones, A Kuo, ... Chemistry–A European Journal 25 (11), 2729-2734, 2019 | 28 | 2019 |
γ-Glutamyl carboxylase mutations differentially affect the biological function of vitamin K–dependent proteins Z Hao, DY Jin, X Chen, LJ Schurgers, DW Stafford, JK Tie Blood, The Journal of the American Society of Hematology 137 (4), 533-543, 2021 | 26 | 2021 |