A transient three-plasmid expression system for the production of high titer retroviral vectors Y Soneoka, PM Cannon, EE Ramsdale, JC Griffiths, G Romano, ... Nucleic acids research 23 (4), 628-633, 1995 | 1005 | 1995 |
Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo N Holt, J Wang, K Kim, G Friedman, X Wang, V Taupin, GM Crooks, ... Nature biotechnology 28 (8), 839-847, 2010 | 830 | 2010 |
International AIDS Society global scientific strategy: towards an HIV cure 2016 SG Deeks, SR Lewin, AL Ross, J Ananworanich, M Benkirane, P Cannon, ... Nature medicine 22 (8), 839-850, 2016 | 493 | 2016 |
AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges MR Gardner, LM Kattenhorn, HR Kondur, M Von Schaewen, T Dorfman, ... Nature 519 (7541), 87-91, 2015 | 340 | 2015 |
Homology-driven genome editing in hematopoietic stem and progenitor cells using ZFN mRNA and AAV6 donors J Wang, CM Exline, JJ DeClercq, GN Llewellyn, SB Hayward, PWL Li, ... Nature biotechnology 33 (12), 1256-1263, 2015 | 311 | 2015 |
Restoration of type VII collagen expression and function in dystrophic epidermolysis bullosa M Chen, N Kasahara, DR Keene, L Chan, WK Hoeffler, D Finlay, ... Nature genetics 32 (4), 670-675, 2002 | 291 | 2002 |
Inhibition of 53BP1 favors homology-dependent DNA repair and increases CRISPR–Cas9 genome-editing efficiency MD Canny, N Moatti, LCK Wan, A Fradet-Turcotte, D Krasner, ... Nature biotechnology 36 (1), 95-102, 2018 | 256 | 2018 |
Genomic editing of the HIV-1 coreceptor CCR5 in adult hematopoietic stem and progenitor cells using zinc finger nucleases L Li, L Krymskaya, J Wang, J Henley, A Rao, LF Cao, CA Tran, ... Molecular Therapy 21 (6), 1259-1269, 2013 | 216 | 2013 |
HIV-1 Vpu and HIV-2 Env counteract BST-2/tetherin by sequestration in a perinuclear compartment H Hauser, LA Lopez, SJ Yang, JE Oldenburg, CM Exline, JC Guatelli, ... Retrovirology 7, 1-16, 2010 | 201 | 2010 |
Research priorities for an HIV cure: international AIDS society global scientific strategy 2021 SG Deeks, N Archin, P Cannon, S Collins, RB Jones, MAWP de Jong, ... Nature medicine 27 (12), 2085-2098, 2021 | 197 | 2021 |
Delivery methods and compositions for nuclease-mediated genome engineering PM Cannon, CM Exline, MC Holmes US Patent 10,604,771, 2020 | 149 | 2020 |
Sequences in the cytoplasmic tail of the gibbon ape leukemia virus envelope protein that prevent its incorporation into lentivirus vectors I Christodoulopoulos, PM Cannon Journal of Virology 75 (9), 4129-4138, 2001 | 147 | 2001 |
Ebola virus glycoprotein counteracts BST-2/Tetherin restriction in a sequence-independent manner that does not require tetherin surface removal LA Lopez, SJ Yang, H Hauser, CM Exline, KG Haworth, J Oldenburg, ... Journal of virology 84 (14), 7243-7255, 2010 | 145 | 2010 |
Human immunodeficiency virus type 1 integrase: effect on viral replication of mutations at highly conserved residues PM Cannon, W Wilson, E Byles, SM Kingsman, AJ Kingsman Journal of virology 68 (8), 4768-4775, 1994 | 145 | 1994 |
Functional analysis of the cytoplasmic tail of Moloney murine leukemia virus envelope protein MM Januszeski, PM Cannon, D Chen, Y Rozenberg, WF Anderson Journal of virology 71 (5), 3613-3619, 1997 | 140 | 1997 |
New world clade B arenaviruses can use transferrin receptor 1 (TfR1)-dependent and-independent entry pathways, and glycoproteins from human pathogenic strains are associated … ML Flanagan, J Oldenburg, T Reignier, N Holt, GA Hamilton, VK Martin, ... Journal of virology 82 (2), 938-948, 2008 | 133 | 2008 |
Preclinical development and qualification of ZFN-mediated CCR5 disruption in human hematopoietic stem/progenitor cells DL DiGiusto, PM Cannon, MC Holmes, L Li, A Rao, J Wang, G Lee, ... Molecular therapy Methods & clinical development 3, 2016 | 126 | 2016 |
Chemokine receptor 5 knockout strategies P Cannon, C June Current Opinion in HIV and AIDS 6 (1), 74-79, 2011 | 118 | 2011 |
Structure-function studies of the human immunodeficiency virus type 1 matrix protein, p17 PM Cannon, S Matthews, N Clark, ED Byles, O Iourin, DJ Hockley, ... Journal of virology 71 (5), 3474-3483, 1997 | 118 | 1997 |
Genome editing technologies: defining a path to clinic: genomic editing: establishing preclinical toxicology standards, bethesda, maryland 10 June 2014 J Corrigan-Curay, M O'reilly, DB Kohn, PM Cannon, G Bao, FD Bushman, ... Molecular therapy 23 (5), 796-806, 2015 | 114 | 2015 |