HBEGF-TNF induce a complex outer retinal pathology with photoreceptor cell extrusion in human organoids M Völkner, F Wagner, LM Steinheuer, M Carido, T Kurth, A Yazbeck, ... Nature Communications 13 (1), 6183, 2022 | 30 | 2022 |
Evaluation of two liver treatment strategies in a mouse model of niemann–pick-disease type C1 L Ebner, A Gläser, A Bräuer, M Witt, A Wree, A Rolfs, M Frank, B Vollmar, ... International Journal of Molecular Sciences 19 (4), 972, 2018 | 23 | 2018 |
Mouse retinal organoid growth and maintenance in longer-term culture M Völkner, T Kurth, J Schor, LJA Ebner, L Bardtke, C Kavak, ... Frontiers in cell and developmental biology 9, 645704, 2021 | 21 | 2021 |
Single-cell RNA sequencing of the retina in a model of retinitis pigmentosa reveals early responses to degeneration in rods and cones D Karademir, V Todorova, LJA Ebner, M Samardzija, C Grimm BMC biology 20 (1), 86, 2022 | 20 | 2022 |
Transcriptomic analysis of the mouse retina after acute and chronic normobaric and hypobaric hypoxia LJA Ebner, M Samardzija, F Storti, V Todorova, D Karademir, J Behr, ... Scientific Reports 11 (1), 16666, 2021 | 14 | 2021 |
Regulation of ABCA1 by AMD-associated genetic variants and hypoxia in iPSC-RPE F Peters, LJA Ebner, D Atac, J Maggi, W Berger, AI den Hollander, ... International Journal of Molecular Sciences 23 (6), 3194, 2022 | 11 | 2022 |
Deficits in mitochondrial TCA cycle and OXPHOS precede rod photoreceptor degeneration during chronic HIF activation V Todorova, MF Stauffacher, L Ravotto, S Nötzli, D Karademir, LJA Ebner, ... Molecular neurodegeneration 18 (1), 15, 2023 | 6 | 2023 |
Modeling inducible neuropathologies of the retina with differential phenotypes in organoids M Völkner, F Wagner, T Kurth, AM Sykes, C Del Toro Runzer, LJA Ebner, ... Frontiers in cellular neuroscience 17, 1106287, 2023 | 5 | 2023 |
HIF1 and DROSHA are involved in MMACHC repression in hypoxia E Kiessling, F Peters, LJA Ebner, L Merolla, M Samardzija, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1866 (9), 130175, 2022 | 5 | 2022 |
Retinal Layer Separation (ReLayS) method enables the molecular analysis of photoreceptor segments and cell bodies, as well as the inner retina V Todorova, L Merolla, D Karademir, GM Wögenstein, J Behr, LJA Ebner, ... Scientific Reports 12 (1), 20195, 2022 | 3 | 2022 |
AAV Serotypes and Their Suitability for Retinal Gene Therapy LJA Ebner, C Grimm Retinal Degenerative Diseases XIX: Mechanisms and Experimental Therapy, 131-134, 2023 | 1 | 2023 |
Remarkable metabolic resilience of rod photoreceptors against reduced OXPHOS caused by chronically active HIF transcription factors C Grimm, V Todorva, MF Stauffacher, L Ravotto, S Nötzli, D Karademir, ... Investigative Ophthalmology & Visual Science 64 (8), 3216-3216, 2023 | | 2023 |
“The” Hypoxic Response in the Mouse Retina Targeted by a Novel Dual-acting Gene Therapy to Preserve Vision LJA Ebner Universität Zürich, 2023 | | 2023 |
Single-cell RNA sequencing of the hypoxic retina identifies an oxygen-dependent isoform switch in RNA-binding proteins and a cone-specific motor protein LJA Ebner, D Karademir, F Peters, C Grimm Investigative Ophthalmology & Visual Science 63 (7), 4613–F0405-4613–F0405, 2022 | | 2022 |
Single-cell RNA sequencing reveals early responses to degeneration in rods and cones of the rd10 retina D Karademir, V Todorova, M Samardzija, LJA Ebner, C Grimm Investigative Ophthalmology & Visual Science 62 (8), 461-461, 2021 | | 2021 |
Photoreceptors harbor the ability for vector-free uptake of molecules following subretinal injection in mice M Ader, L Ebner, S Gasparini, T Santos-Ferreira, O Borsch Investigative Ophthalmology & Visual Science 61 (7), 734-734, 2020 | | 2020 |