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Lynn J. A. Ebner
Lynn J. A. Ebner
Postdoctoral Scientist F. Hoffmann-La Roche
在 roche.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
HBEGF-TNF induce a complex outer retinal pathology with photoreceptor cell extrusion in human organoids
M Völkner, F Wagner, LM Steinheuer, M Carido, T Kurth, A Yazbeck, ...
Nature Communications 13 (1), 6183, 2022
302022
Evaluation of two liver treatment strategies in a mouse model of niemann–pick-disease type C1
L Ebner, A Gläser, A Bräuer, M Witt, A Wree, A Rolfs, M Frank, B Vollmar, ...
International Journal of Molecular Sciences 19 (4), 972, 2018
232018
Mouse retinal organoid growth and maintenance in longer-term culture
M Völkner, T Kurth, J Schor, LJA Ebner, L Bardtke, C Kavak, ...
Frontiers in cell and developmental biology 9, 645704, 2021
212021
Single-cell RNA sequencing of the retina in a model of retinitis pigmentosa reveals early responses to degeneration in rods and cones
D Karademir, V Todorova, LJA Ebner, M Samardzija, C Grimm
BMC biology 20 (1), 86, 2022
202022
Transcriptomic analysis of the mouse retina after acute and chronic normobaric and hypobaric hypoxia
LJA Ebner, M Samardzija, F Storti, V Todorova, D Karademir, J Behr, ...
Scientific Reports 11 (1), 16666, 2021
142021
Regulation of ABCA1 by AMD-associated genetic variants and hypoxia in iPSC-RPE
F Peters, LJA Ebner, D Atac, J Maggi, W Berger, AI den Hollander, ...
International Journal of Molecular Sciences 23 (6), 3194, 2022
112022
Deficits in mitochondrial TCA cycle and OXPHOS precede rod photoreceptor degeneration during chronic HIF activation
V Todorova, MF Stauffacher, L Ravotto, S Nötzli, D Karademir, LJA Ebner, ...
Molecular neurodegeneration 18 (1), 15, 2023
62023
Modeling inducible neuropathologies of the retina with differential phenotypes in organoids
M Völkner, F Wagner, T Kurth, AM Sykes, C Del Toro Runzer, LJA Ebner, ...
Frontiers in cellular neuroscience 17, 1106287, 2023
52023
HIF1 and DROSHA are involved in MMACHC repression in hypoxia
E Kiessling, F Peters, LJA Ebner, L Merolla, M Samardzija, ...
Biochimica et Biophysica Acta (BBA)-General Subjects 1866 (9), 130175, 2022
52022
Retinal Layer Separation (ReLayS) method enables the molecular analysis of photoreceptor segments and cell bodies, as well as the inner retina
V Todorova, L Merolla, D Karademir, GM Wögenstein, J Behr, LJA Ebner, ...
Scientific Reports 12 (1), 20195, 2022
32022
AAV Serotypes and Their Suitability for Retinal Gene Therapy
LJA Ebner, C Grimm
Retinal Degenerative Diseases XIX: Mechanisms and Experimental Therapy, 131-134, 2023
12023
Remarkable metabolic resilience of rod photoreceptors against reduced OXPHOS caused by chronically active HIF transcription factors
C Grimm, V Todorva, MF Stauffacher, L Ravotto, S Nötzli, D Karademir, ...
Investigative Ophthalmology & Visual Science 64 (8), 3216-3216, 2023
2023
“The” Hypoxic Response in the Mouse Retina Targeted by a Novel Dual-acting Gene Therapy to Preserve Vision
LJA Ebner
Universität Zürich, 2023
2023
Single-cell RNA sequencing of the hypoxic retina identifies an oxygen-dependent isoform switch in RNA-binding proteins and a cone-specific motor protein
LJA Ebner, D Karademir, F Peters, C Grimm
Investigative Ophthalmology & Visual Science 63 (7), 4613–F0405-4613–F0405, 2022
2022
Single-cell RNA sequencing reveals early responses to degeneration in rods and cones of the rd10 retina
D Karademir, V Todorova, M Samardzija, LJA Ebner, C Grimm
Investigative Ophthalmology & Visual Science 62 (8), 461-461, 2021
2021
Photoreceptors harbor the ability for vector-free uptake of molecules following subretinal injection in mice
M Ader, L Ebner, S Gasparini, T Santos-Ferreira, O Borsch
Investigative Ophthalmology & Visual Science 61 (7), 734-734, 2020
2020
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