CD7-edited T cells expressing a CD7-specific CAR for the therapy of T-cell malignancies D Gomes-Silva, M Srinivasan, S Sharma, CM Lee, DL Wagner, TH Davis, ... Blood 130 (3), 285-296, 2017 | 384 | 2017 |
High prevalence of Streptococcus pyogenes Cas9-reactive T cells within the adult human population DL Wagner, L Amini, DJ Wendering, LM Burkhardt, L Akyüz, P Reinke, ... Nature Medicine, 1, 2018 | 381 | 2018 |
Highly efficient genome editing of murine and human hematopoietic progenitor cells by CRISPR/Cas9 MC Gundry, L Brunetti, A Lin, AE Mayle, A Kitano, D Wagner, JI Hsu, ... Cell reports 17 (5), 1453-1461, 2016 | 281 | 2016 |
Constitutive signaling from an engineered IL7 receptor promotes durable tumor elimination by tumor-redirected T cells T Shum, B Omer, H Tashiro, RL Kruse, DL Wagner, K Parikh, Z Yi, ... Cancer discovery 7 (11), 1238-1247, 2017 | 251 | 2017 |
Immunogenicity of CAR T cells in cancer therapy DL Wagner, E Fritsche, MA Pulsipher, N Ahmed, M Hamieh, M Hegde, ... Nature Reviews Clinical Oncology 18 (6), 379-393, 2021 | 181 | 2021 |
CAR T-cells that target acute B-lineage leukemia irrespective of CD19 expression K Fousek, J Watanabe, SK Joseph, A George, X An, TT Byrd, JS Morris, ... Leukemia 35 (1), 75-89, 2021 | 147 | 2021 |
Regulatory T cells for minimising immune suppression in kidney transplantation: phase I/IIa clinical trial A Roemhild, NM Otto, G Moll, M Abou-El-Enein, D Kaiser, G Bold, ... bmj 371, 2020 | 146 | 2020 |
Overcoming on-target, off-tumour toxicity of CAR T cell therapy for solid tumours CL Flugel, RG Majzner, G Krenciute, G Dotti, SR Riddell, DL Wagner, ... Nature Reviews Clinical Oncology 20 (1), 49-62, 2023 | 143 | 2023 |
PAX5 biallelic genomic alterations define a novel subgroup of B-cell precursor acute lymphoblastic leukemia L Bastian, MP Schroeder, C Eckert, C Schlee, JO Tanchez, S Kämpf, ... Leukemia 33 (8), 1895-1909, 2019 | 58 | 2019 |
Pharmacological interventions enhance virus-free generation of TRAC-replaced CAR T cells J Kath, W Du, A Pruene, T Braun, B Thommandru, R Turk, ML Sturgeon, ... Molecular Therapy-Methods & Clinical Development 25, 311-330, 2022 | 45* | 2022 |
Cas9-directed immune tolerance in humans—a model to evaluate regulatory T cells in gene therapy? DL Wagner, L Peter, M Schmueck-Henneresse Gene therapy 28 (9), 549-559, 2021 | 39 | 2021 |
Super-Treg: toward a new era of adoptive Treg therapy enabled by genetic modifications L Amini, J Greig, M Schmueck-Henneresse, HD Volk, S Bézie, P Reinke, ... Frontiers in Immunology 11, 611638, 2021 | 38 | 2021 |
CRISPR-Cas9-edited tacrolimus-resistant antiviral T cells for advanced adoptive immunotherapy in transplant recipients L Amini, DL Wagner, U Rössler, G Zarrinrad, LF Wagner, T Vollmer, ... Molecular Therapy 29 (1), 32-46, 2021 | 37 | 2021 |
sustainable clinical development of CAR-T cells–switching from viral transduction towards CRISPR-Cas gene editing DL Wagner, U Koehl, M Chmielewski, C Scheid, R Stripecke Frontiers in Immunology 13, 865424, 2022 | 32 | 2022 |
Combining different CRISPR nucleases for simultaneous knock-in and base editing prevents translocations in multiplex-edited CAR T cells V Glaser, C Flugel, J Kath, W Du, V Drosdek, C Franke, M Stein, A Pruß, ... Genome Biology 24 (1), 89, 2023 | 18 | 2023 |
Daratumumab for the treatment of refractory ANCA-associated vasculitis L Ostendorf, M Burns, DL Wagner, P Enghard, K Amann, H Mei, ... RMD open 9 (1), e002742, 2023 | 17 | 2023 |
Tacrolimus-resistant SARS-CoV-2-specific T cell products to prevent and treat severe COVID-19 in immunosuppressed patients L Peter, DJ Wendering, S Schlickeiser, H Hoffmann, R Noster, DL Wagner, ... Molecular Therapy-Methods & Clinical Development 25, 52-73, 2022 | 15 | 2022 |
Central memory phenotype drives success of checkpoint inhibition in combination with CAR T cells K Toews, L Grunewald, S Schwiebert, A Klaus, A Winkler, S Ali, F Zirngibl, ... Molecular Carcinogenesis 59 (7), 724-735, 2020 | 12 | 2020 |
Barring the gates to the battleground: DDR1 promotes immune exclusion in solid tumors DL Wagner, E Klotzsch Signal Transduction and Targeted Therapy 7 (1), 17, 2022 | 7 | 2022 |
Non-viral TRAC-knocked-in CD19KICAR-T and gp350KICAR-T cells tested against Burkitt lymphomas with type 1 or 2 EBV infection: In vivo cellular dynamics and potency T Braun, A Pruene, M Darguzyte, AF Vom Stein, PH Nguyen, DL Wagner, ... Frontiers in Immunology 14, 1086433, 2023 | 5 | 2023 |