Profiling dose-dependent activation of p53-mediated signaling pathways by chemicals with distinct mechanisms of DNA damage RA Clewell, B Sun, Y Adeleye, P Carmichael, A Efremenko, PD McMullen, ... Toxicological sciences 142 (1), 56-73, 2014 | 56 | 2014 |
Developing context appropriate toxicity testing approaches using new alternative methods (NAMs) ME Andersen, PD McMullen, MB Phillips, M Yoon, SN Pendse, ... ALTEX-Alternatives to animal experimentation 36 (4), 523-534, 2019 | 49 | 2019 |
Development and application of a life-stage physiologically based pharmacokinetic (PBPK) model to the assessment of internal dose of pyrethroids in humans P Mallick, M Moreau, G Song, AY Efremenko, SN Pendse, MR Creek, ... Toxicological Sciences 173 (1), 86-99, 2020 | 39 | 2020 |
Editor’s Highlight: Screening ToxCast Prioritized Chemicals for PPARG Function in a Human Adipose-Derived Stem Cell Model of Adipogenesis B Foley, DL Doheny, MB Black, SN Pendse, BA Wetmore, RA Clewell, ... Toxicological Sciences 155 (1), 85-100, 2017 | 36 | 2017 |
MYC is an early response regulator of human adipogenesis in adipose stem cells C Deisenroth, MB Black, S Pendse, L Pluta, SM Witherspoon, ... PLoS One 9 (12), e114133, 2014 | 30 | 2014 |
Assessing molecular initiating events (MIEs), key events (KEs) and modulating factors (MFs) for styrene responses in mouse lungs using whole genome gene expression profiling … ME Andersen, G Cruzan, MB Black, SN Pendse, D Dodd, JS Bus, ... Toxicology and applied pharmacology 335, 28-40, 2017 | 28 | 2017 |
Using exposure prediction tools to link exposure and dosimetry for risk-based decisions: A case study with phthalates M Moreau, J Leonard, KA Phillips, J Campbell, SN Pendse, C Nicolas, ... Chemosphere 184, 1194-1201, 2017 | 26 | 2017 |
Information-dependent enrichment analysis reveals time-dependent transcriptional regulation of the estrogen pathway of toxicity SN Pendse, A Maertens, M Rosenberg, D Roy, RA Fasani, ... Archives of Toxicology 91, 1749-1762, 2017 | 25 | 2017 |
Combining transcriptomics and PBPK modeling indicates a primary role of hypoxia and altered circadian signaling in dichloromethane carcinogenicity in mouse lung and liver ME Andersen, MB Black, JL Campbell, SN Pendse, HJ Clewell III, ... Toxicology and applied pharmacology 332, 149-158, 2017 | 24 | 2017 |
Identifying qualitative differences in PPARα signaling networks in human and rat hepatocytes and their significance for next generation chemical risk assessment methods PD McMullen, S Bhattacharya, CG Woods, SN Pendse, MT McBride, ... Toxicology in Vitro 64, 104463, 2020 | 23 | 2020 |
Addressing systematic inconsistencies between in vitro and in vivo transcriptomic mode of action signatures PD McMullen, SN Pendse, MB Black, K Mansouri, S Haider, ME Andersen, ... Toxicology in Vitro 58, 1-12, 2019 | 23 | 2019 |
Population Life-course exposure to health effects model (PLETHEM): An R package for PBPK modeling SN Pendse, A Efremenko, CE Hack, M Moreau, P Mallick, M Dzierlenga, ... Computational Toxicology 13, 100115, 2020 | 19 | 2020 |
Using gene expression profiling to evaluate cellular responses in mouse lungs exposed to V2O5 and a group of other mouse lung tumorigens and non-tumorigens MB Black, DE Dodd, PD McMullen, S Pendse, JA MacGregor, ... Regulatory Toxicology and Pharmacology 73 (1), 339-347, 2015 | 15 | 2015 |
Application of transcriptomic data, visualization tools and bioinformatics resources for informing mode of action ME Andersen, SN Pendse, MB Black, PD McMullen Current Opinion in Toxicology 9, 21-27, 2018 | 14 | 2018 |
Physiologically based pharmacokinetic modeling software CE Hack, AY Efremenko, SN Pendse, CA Ellison, A Najjar, N Hewitt, ... Physiologically Based Pharmacokinetic (PBPK) Modeling, 81-126, 2020 | 12 | 2020 |
Assessing bioactivity-exposure profiles of fruit and vegetable extracts in the BioMAP profiling system BA Wetmore, RA Clewell, B Cholewa, B Parks, SN Pendse, MB Black, ... Toxicology in Vitro 54, 41-57, 2019 | 12 | 2019 |
Strain-related differences in mouse lung gene expression over a two-year period of inhalation exposure to styrene: Relevance to human risk assessment ME Andersen, G Cruzan, MB Black, SN Pendse, DE Dodd, JS Bus, ... Regulatory Toxicology and Pharmacology 96, 153-166, 2018 | 12 | 2018 |
The human toxome collaboratorium: A shared environment for multi-omic computational collaboration within a consortium RA Fasani, CB Livi, DR Choudhury, A Kleensang, M Bouhifd, SN Pendse, ... Frontiers in Pharmacology 6, 322, 2016 | 12 | 2016 |
An interactive visualization tool to interpret transcriptomics data S Pendse, PD McMullen Proceedings of the International Conference on Bioinformatics …, 2014 | 12 | 2014 |
Considerations for Improving Metabolism Predictions for In Vitro to In Vivo Extrapolation M Moreau, P Mallick, M Smeltz, S Haider, CI Nicolas, SN Pendse, ... Frontiers in Toxicology 4, 894569, 2022 | 9 | 2022 |