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Ewing sarcoma 11; 22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation. WA May, ML Gishizky, SL Lessnick, LB Lunsford, BC Lewis, O Delattre, ... Proceedings of the National Academy of Sciences 90 (12), 5752-5756, 1993 | 691 | 1993 |
The Ewing’s Sarcoma EWS/FLI-1 Fusion Gene Encodes a More Potent Transcriptional Activator and is a More Powerful Transforming Gene than FLI-1 WA May, SL Lessnick, BS Braun, M Klemsz, BC Lewis, LB Lunsford, ... Molecular and cellular biology 13 (12), 7393-7398, 1993 | 654 | 1993 |
A variant Ewing's sarcoma translocation (7; 22) fuses the EWS gene to the ETS gene ETV1 IS Jeon, JN Davis, BS Braun, JE Sublett, MF Roussel, CT Denny, ... Oncogene 10 (6), 1229-1234, 1995 | 647 | 1995 |
Leukemia and the disruption of normal hematopoiesis CL Sawyers, CT Denny, ON Witte Cell 64 (2), 337-350, 1991 | 511 | 1991 |
Biology of EWS/ETS fusions in Ewing's family tumors A Arvand, CT Denny Oncogene 20 (40), 5747-5754, 2001 | 411 | 2001 |
Detection of differentially expressed genes in primary tumor tissues using representational differences analysis coupled to microarray hybridization SM Welford, J Gregg, E Chen, D Garrison, PH Sorensen, CT Denny, ... Nucleic acids research 26 (12), 3059-3065, 1998 | 268 | 1998 |
Multiple domains mediate transformation by the Ewing's sarcoma EWS/FLI-1 fusion gene SL Lessnick, BS Braun, CT Denny, WA May Oncogene 10 (3), 423-432, 1995 | 258 | 1995 |
Identification of target genes for the Ewing's sarcoma EWS/FLI fusion protein by representational difference analysis BS Braun, R Frieden, SL Lessnick, WA May, CT Denny Molecular and Cellular Biology, 1995 | 234 | 1995 |
Oncogenic MITF dysregulation in clear cell sarcoma: defining the MiT family of human cancers IJ Davis, JJ Kim, F Ozsolak, HR Widlund, O Rozenblatt-Rosen, ... Cancer cell 9 (6), 473-484, 2006 | 227 | 2006 |
EWS/FLI1-induced manic fringe renders NIH 3T3 cells tumorigenic WA May, A Arvand, AD Thompson, BS Braun, M Wright, CT Denny Nature genetics 17 (4), 495-497, 1997 | 202 | 1997 |
Structural basis for the interaction of the free SH2 domain EAT‐2 with SLAM receptors in hematopoietic cells M Morra, J Lu, F Poy, M Martin, J Sayos, S Calpe, C Gullo, D Howie, ... The EMBO journal, 2001 | 198 | 2001 |
Loss of p16 pathways stabilizes EWS/FLI1 expression and complements EWS/FLI1 mediated transformation B Deneen, CT Denny Oncogene 20 (46), 6731-6741, 2001 | 164 | 2001 |
A chromosome 14 inversion in a T-cell lymphoma is caused by site-specific recombination between immunoglobulin and T-cell receptor loci CT Denny, Y Yoshikai, TW Mak, SD Smith, GF Hollis, IR Kirsch Nature 320 (6062), 549-551, 1986 | 163 | 1986 |
EAT-2 is a novel SH2 domain containing protein that is up regulated by Ewing's sarcoma EWS/FLI1 fusion gene AD Thompson, BS Braun, A Arvand, SD Stewart, WA May, E Chen, ... Oncogene 13 (12), 2649-2658, 1996 | 156 | 1996 |
EWS-FLI1, EWS-ERG, and EWS-ETV1 oncoproteins of Ewing tumor family all suppress transcription of transforming growth factor β type II receptor gene YH Im, HT Kim, C Lee, D Poulin, S Welford, PHB Sorensen, CT Denny, ... Cancer research 60 (6), 1536-1540, 2000 | 145 | 2000 |
Divergent Ewing's sarcoma EWS/ETS fusions confer a common tumorigenic phenotype on NIH3T3 cells AD Thompson, MA Teitell, A Arvand, CT Denny Oncogene 18 (40), 5506-5513, 1999 | 139 | 1999 |
EWS/FLI1 up regulates mE2-C, a cyclin-selective ubiquitin conjugating enzyme involved in cyclin B destruction A Arvand, H Bastians, SM Welford, AD Thompson, JV Ruderman, ... Oncogene 17 (16), 2039-2045, 1998 | 127 | 1998 |
Chronic myelomonocytic leukemia: Tel-a-kinase what Ets all about CL Sawyers, CT Denny Cell 77 (2), 171-173, 1994 | 115 | 1994 |
Multiple aromatic side chains within a disordered structure are critical for transcription and transforming activity of EWS family oncoproteins KP Ng, G Potikyan, ROV Savene, CT Denny, VN Uversky, KAW Lee Proceedings of the National Academy of Sciences 104 (2), 479-484, 2007 | 113 | 2007 |