| Neutrophil elastase activates protease-activated receptor-2 (PAR2) and transient receptor potential vanilloid 4 (TRPV4) to cause inflammation and pain P Zhao, TM Lieu, N Barlow, S Sostegni, S Haerteis, C Korbmacher, ... Journal of Biological Chemistry 290 (22), 13875-13887, 2015 | 166 | 2015 |
| Protease-activated receptor-2 in endosomes signals persistent pain of irritable bowel syndrome NN Jimenez-Vargas, LA Pattison, P Zhao, TM Lieu, R Latorre, DD Jensen, ... Proceedings of the National Academy of Sciences 115 (31), E7438-E7447, 2018 | 151 | 2018 |
| Endosomal signaling of delta opioid receptors is an endogenous mechanism and therapeutic target for relief from inflammatory pain NN Jimenez-Vargas, J Gong, MJ Wisdom, DD Jensen, R Latorre, ... Proceedings of the National Academy of Sciences 117 (26), 15281-15292, 2020 | 85 | 2020 |
| Histamine production by the gut microbiota induces visceral hyperalgesia through histamine 4 receptor signaling in mice G De Palma, C Shimbori, DE Reed, Y Yu, V Rabbia, J Lu, ... Science Translational Medicine 14 (655), eabj1895, 2022 | 59 | 2022 |
| Legumain induces oral cancer pain by biased agonism of protease-activated receptor-2 NH Tu, DD Jensen, BM Anderson, E Chen, NN Jimenez-Vargas, ... Journal of Neuroscience 41 (1), 193-210, 2021 | 41 | 2021 |
| Agonist that activates the µ-opioid receptor in acidified microenvironments inhibits colitis pain without side effects NN Jiménez-Vargas, Y Yu, DD Jensen, DD Bok, M Wisdom, R Latorre, ... Gut 71 (4), 695-704, 2022 | 37 | 2022 |
| Stress activates pronociceptive endogenous opioid signalling in DRG neurons during chronic colitis R Guerrero-Alba, EE Valdez-Morales, NN Jimenez-Vargas, ... Gut 66 (12), 2121-2131, 2017 | 37 | 2017 |
| Protein kinase D and Gβγ subunits mediate agonist-evoked translocation of protease-activated receptor-2 from the Golgi apparatus to the plasma membrane DD Jensen, P Zhao, NN Jimenez-Vargas, TM Lieu, M Gerges, ... Journal of Biological Chemistry 291 (21), 11285-11299, 2016 | 26 | 2016 |
| Co‐expression of μ and δ opioid receptors by mouse colonic nociceptors R Guerrero‐Alba, EE Valdez‐Morales, NN Jiménez‐Vargas, R Bron, ... British Journal of Pharmacology 175 (13), 2622-2634, 2018 | 25 | 2018 |
| Inhibition of extracellular nucleotides hydrolysis intensifies the allergic bronchospasm. A novel protective role of ectonucleotidases J Chávez, MH Vargas, DC Rebollar‐Ayala, V Díaz‐Hernández, ... Allergy 68 (4), 462-471, 2013 | 22 | 2013 |
| The impact of dietary fermentable carbohydrates on a postinflammatory model of irritable bowel syndrome CJ Tuck, A Caminero, NN Jiménez Vargas, CL Soltys, ... Neurogastroenterology & Motility 31 (10), e13675, 2019 | 15 | 2019 |
| Changes in signalling from faecal neuroactive metabolites following dietary modulation of IBS pain CJ Tuck, AA Omar, G De Palma, S Osman, NN Jiménez-Vargas, Y Yu, ... Gut 72 (9), 1678-1691, 2023 | 14 | 2023 |
| Neutrophil elastase activates PAR2 and TRPV4 to cause inflammation and pain P Zhao, T Lieu, N Barlow, S Sostegni, S Haerteis, C Korbmacher, ... J Biol Chem 290, 13875-13887, 2015 | 13 | 2015 |
| Protein kinase D and Gβγ mediate sustained nociceptive signaling by biased agonists of protease-activated receptor-2 P Zhao, LA Pattison, DD Jensen, NN Jimenez-Vargas, R Latorre, TM Lieu, ... Journal of Biological Chemistry 294 (27), 10649-10662, 2019 | 12 | 2019 |
| Expression of P2X3 and P2X5 Myenteric Receptors Varies During the Intestinal Postnatal Development in the Guinea Pig R Loera-Valencia, NN Jiménez-Vargas, EC Villalobos, EH Juárez, ... Cellular and molecular neurobiology 34, 727-736, 2014 | 8 | 2014 |
| Dietary monosodium glutamate increases visceral hypersensitivity in a mouse model of visceral pain BJA Brant, Y Yu, AA Omar, JO Jaramillo Polanco, CD Lopez Lopez, ... Neurogastroenterology & Motility 35 (9), e14596, 2023 | 3 | 2023 |
| 916-Gut microbiota-diet interactions in a humanized mouse model of IBS: the role of intestinal mast cells C Shimbori, G De Palma, DE Reed, M Pigrau, J Lu, Y Zhang, Y Yu, ... Gastroenterology 154 (6), S-182, 2018 | 3 | 2018 |
| Diet-Microbiota Interactions Underlie Symptoms' Generation in IBS G De Palma, DE Reed, M Pigrau, J Lu, S Sidani, Y Zhang, Y Yu, ... Gastroenterology 152 (5), S160, 2017 | 3 | 2017 |
| Evolving acidic microenvironments during colitis provide selective analgesic targets for a pH-sensitive opioid CE Degro, NN Jiménez-Vargas, Q Tsang, Y Yu, M Guzman-Rodriguez, ... Pain 164 (11), 2501-2515, 2023 | 2 | 2023 |
| Su1658-Gut Microbiota Defines Host Responses to Dietary Fermentable Carbohydrates in IBS: The Role of Bacterial Histamine G De Palma, DE Reed, C Shimbori, Y Zhang, M Pigrau, Y Yu, J Lu, ... Gastroenterology 154 (6), S-565, 2018 | 2 | 2018 |
