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Rachelle Irwin
Rachelle Irwin
Lecturer in Genomic Medicine
在 ulster.ac.uk 的电子邮件经过验证
标题
引用次数
引用次数
年份
Gene-specific DNA methylation in newborns in response to folic acid supplementation during the second and third trimesters of pregnancy: epigenetic analysis from a randomized …
A Caffrey, RE Irwin, H McNulty, JJ Strain, DJ Lees-Murdock, BA McNulty, ...
The American journal of clinical nutrition 107 (4), 566-575, 2018
1132018
The interplay between DNA methylation, folate and neurocognitive development
RE Irwin, K Pentieva, T Cassidy, DJ Lees-Murdock, M McLaughlin, ...
Epigenomics 8 (6), 863-879, 2016
812016
Maternal folate nutrition and offspring health: evidence and current controversies
A Caffrey, H McNulty, RE Irwin, CP Walsh, K Pentieva
Proceedings of the Nutrition Society 78 (2), 208-220, 2019
542019
A randomized controlled trial of folic acid intervention in pregnancy highlights a putative methylation-regulated control element at ZFP57
RE Irwin, SJ Thursby, M Ondičová, K Pentieva, H McNulty, RC Richmond, ...
Clinical Epigenetics 11, 1-16, 2019
472019
5-Hydroxymethylation marks a class of neuronal gene regulated by intragenic methylcytosine levels
RE Irwin, A Thakur, KM O'Neill, CP Walsh
Genomics 104 (5), 383-392, 2014
332014
Ontogeny, conservation and functional significance of maternally inherited DNA methylation at two classes of non-imprinted genes
CE Rutledge, A Thakur, KM O’Neill, RE Irwin, S Sato, K Hata, CP Walsh
Development 141 (6), 1313-1323, 2014
282014
The metabolic-epigenetic nexus in type 2 diabetes mellitus
GW Davison, RE Irwin, CP Walsh
Free Radical Biology and Medicine 170, 194-206, 2021
272021
Folic acid intervention during pregnancy alters DNA methylation, affecting neural target genes through two distinct mechanisms
M Ondičová, RE Irwin, SJ Thursby, L Hilman, A Caffrey, T Cassidy, ...
Clinical Epigenetics 14 (1), 63, 2022
262022
Depletion of DNMT1 in differentiated human cells highlights key classes of sensitive genes and an interplay with polycomb repression
KM O’Neill, RE Irwin, SJ Mackin, SJ Thursby, A Thakur, C Bertens, ...
Epigenetics & chromatin 11, 1-21, 2018
242018
Intragenic sequences in the trophectoderm harbour the greatest proportion of methylation errors in day 17 bovine conceptuses generated using assisted reproductive technologies
AM O’Doherty, P McGettigan, RE Irwin, DA Magee, D Gagne, E Fournier, ...
BMC genomics 19, 1-15, 2018
212018
Exercise is associated with younger methylome and transcriptome profiles in human skeletal muscle
S Voisin, K Seale, M Jacques, S Landen, NR Harvey, LM Haupt, ...
Aging Cell 23 (1), e13859, 2024
192024
Low birth weight female piglets show altered intestinal development, gene expression, and epigenetic changes at key developmental loci
M Ayuso, R Irwin, C Walsh, S Van Cruchten, C Van Ginneken
The FASEB Journal 35 (4), e21522, 2021
172021
The bovine alveolar macrophage DNA methylome is resilient to infection with Mycobacterium bovis
AM o’Doherty, KC Rue-Albrecht, DA Magee, S Ahting, RE Irwin, TJ Hall, ...
Scientific Reports 9 (1), 1510, 2019
112019
Widespread recovery of methylation at gametic imprints in hypomethylated mouse stem cells following rescue with DNMT3A2
A Thakur, SJ Mackin, RE Irwin, KM O’Neill, G Pollin, C Walsh
Epigenetics & Chromatin 9, 1-15, 2016
102016
Methylome profiling of young adults with depression supports a link with immune response and psoriasis
CR Lapsley, R Irwin, M McLafferty, SJ Thursby, SM O’Neill, AJ Bjourson, ...
Clinical Epigenetics 12, 1-16, 2020
92020
CandiMeth: powerful yet simple visualization and quantification of DNA methylation at candidate genes
SJ Thursby, DK Lobo, K Pentieva, SD Zhang, RE Irwin, CP Walsh
GigaScience 9 (6), giaa066, 2020
52020
Effect of folic acid supplementation in pregnancy on gene specific DNA methylation in the child: evidence from a randomised controlled trial
A Caffrey, H McNulty, C Walsh, R Irwin, K Pentieva
Proceedings of the Nutrition Society 75 (OCE3), E132, 2016
52016
The UHRF1 protein is a key regulator of retrotransposable elements and innate immune response to viral RNA in human cells
RE Irwin, C Scullion, SJ Thursby, M Sun, A Thakur, L Hilman, B Callaghan, ...
Epigenetics 18 (1), 2216005, 2023
32023
Epigenetic effects of folate and related B vitamins on brain health throughout life: Scientific substantiation and translation of the evidence for health improvement strategies
A Caffrey, Y Lamers, MM Murphy, N Letourneau, RE Irwin, K Pentieva, ...
Nutrition Bulletin 48 (2), 267-277, 2023
32023
Impact of folic acid supplementation during pregnancy on cognitive performance of children at age 11 years: Preliminary results from the FASSTT Offspring study
A Caffrey, H McNulty, R Irwin, T Cassidy, M McLaughlin, D Lees-Murdock, ...
Proceedings of the Nutrition Society 77 (OCE3), E98, 2018
32018
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