Gene-specific DNA methylation in newborns in response to folic acid supplementation during the second and third trimesters of pregnancy: epigenetic analysis from a randomized … A Caffrey, RE Irwin, H McNulty, JJ Strain, DJ Lees-Murdock, BA McNulty, ... The American journal of clinical nutrition 107 (4), 566-575, 2018 | 113 | 2018 |
The interplay between DNA methylation, folate and neurocognitive development RE Irwin, K Pentieva, T Cassidy, DJ Lees-Murdock, M McLaughlin, ... Epigenomics 8 (6), 863-879, 2016 | 81 | 2016 |
Maternal folate nutrition and offspring health: evidence and current controversies A Caffrey, H McNulty, RE Irwin, CP Walsh, K Pentieva Proceedings of the Nutrition Society 78 (2), 208-220, 2019 | 54 | 2019 |
A randomized controlled trial of folic acid intervention in pregnancy highlights a putative methylation-regulated control element at ZFP57 RE Irwin, SJ Thursby, M Ondičová, K Pentieva, H McNulty, RC Richmond, ... Clinical Epigenetics 11, 1-16, 2019 | 47 | 2019 |
5-Hydroxymethylation marks a class of neuronal gene regulated by intragenic methylcytosine levels RE Irwin, A Thakur, KM O'Neill, CP Walsh Genomics 104 (5), 383-392, 2014 | 33 | 2014 |
Ontogeny, conservation and functional significance of maternally inherited DNA methylation at two classes of non-imprinted genes CE Rutledge, A Thakur, KM O’Neill, RE Irwin, S Sato, K Hata, CP Walsh Development 141 (6), 1313-1323, 2014 | 28 | 2014 |
The metabolic-epigenetic nexus in type 2 diabetes mellitus GW Davison, RE Irwin, CP Walsh Free Radical Biology and Medicine 170, 194-206, 2021 | 27 | 2021 |
Folic acid intervention during pregnancy alters DNA methylation, affecting neural target genes through two distinct mechanisms M Ondičová, RE Irwin, SJ Thursby, L Hilman, A Caffrey, T Cassidy, ... Clinical Epigenetics 14 (1), 63, 2022 | 26 | 2022 |
Depletion of DNMT1 in differentiated human cells highlights key classes of sensitive genes and an interplay with polycomb repression KM O’Neill, RE Irwin, SJ Mackin, SJ Thursby, A Thakur, C Bertens, ... Epigenetics & chromatin 11, 1-21, 2018 | 24 | 2018 |
Intragenic sequences in the trophectoderm harbour the greatest proportion of methylation errors in day 17 bovine conceptuses generated using assisted reproductive technologies AM O’Doherty, P McGettigan, RE Irwin, DA Magee, D Gagne, E Fournier, ... BMC genomics 19, 1-15, 2018 | 21 | 2018 |
Exercise is associated with younger methylome and transcriptome profiles in human skeletal muscle S Voisin, K Seale, M Jacques, S Landen, NR Harvey, LM Haupt, ... Aging Cell 23 (1), e13859, 2024 | 19 | 2024 |
Low birth weight female piglets show altered intestinal development, gene expression, and epigenetic changes at key developmental loci M Ayuso, R Irwin, C Walsh, S Van Cruchten, C Van Ginneken The FASEB Journal 35 (4), e21522, 2021 | 17 | 2021 |
The bovine alveolar macrophage DNA methylome is resilient to infection with Mycobacterium bovis AM o’Doherty, KC Rue-Albrecht, DA Magee, S Ahting, RE Irwin, TJ Hall, ... Scientific Reports 9 (1), 1510, 2019 | 11 | 2019 |
Widespread recovery of methylation at gametic imprints in hypomethylated mouse stem cells following rescue with DNMT3A2 A Thakur, SJ Mackin, RE Irwin, KM O’Neill, G Pollin, C Walsh Epigenetics & Chromatin 9, 1-15, 2016 | 10 | 2016 |
Methylome profiling of young adults with depression supports a link with immune response and psoriasis CR Lapsley, R Irwin, M McLafferty, SJ Thursby, SM O’Neill, AJ Bjourson, ... Clinical Epigenetics 12, 1-16, 2020 | 9 | 2020 |
CandiMeth: powerful yet simple visualization and quantification of DNA methylation at candidate genes SJ Thursby, DK Lobo, K Pentieva, SD Zhang, RE Irwin, CP Walsh GigaScience 9 (6), giaa066, 2020 | 5 | 2020 |
Effect of folic acid supplementation in pregnancy on gene specific DNA methylation in the child: evidence from a randomised controlled trial A Caffrey, H McNulty, C Walsh, R Irwin, K Pentieva Proceedings of the Nutrition Society 75 (OCE3), E132, 2016 | 5 | 2016 |
The UHRF1 protein is a key regulator of retrotransposable elements and innate immune response to viral RNA in human cells RE Irwin, C Scullion, SJ Thursby, M Sun, A Thakur, L Hilman, B Callaghan, ... Epigenetics 18 (1), 2216005, 2023 | 3 | 2023 |
Epigenetic effects of folate and related B vitamins on brain health throughout life: Scientific substantiation and translation of the evidence for health improvement strategies A Caffrey, Y Lamers, MM Murphy, N Letourneau, RE Irwin, K Pentieva, ... Nutrition Bulletin 48 (2), 267-277, 2023 | 3 | 2023 |
Impact of folic acid supplementation during pregnancy on cognitive performance of children at age 11 years: Preliminary results from the FASSTT Offspring study A Caffrey, H McNulty, R Irwin, T Cassidy, M McLaughlin, D Lees-Murdock, ... Proceedings of the Nutrition Society 77 (OCE3), E98, 2018 | 3 | 2018 |