A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV M Yuan, NC Wu, X Zhu, CCD Lee, RTY So, H Lv, CKP Mok, IA Wilson Science 368 (6491), 630-633, 2020 | 1560 | 2020 |
Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model TF Rogers, F Zhao, D Huang, N Beutler, A Burns, W He, O Limbo, C Smith, ... Science 369 (6506), 956-963, 2020 | 1350 | 2020 |
Structural basis of a shared antibody response to SARS-CoV-2 M Yuan, H Liu, NC Wu, CCD Lee, X Zhu, F Zhao, D Huang, W Yu, Y Hua, ... Science, 2020 | 547 | 2020 |
Cross-reactive antibody response between SARS-CoV-2 and SARS-CoV infections H Lv, NC Wu, OTY Tsang, M Yuan, RAPM Perera, WS Leung, RTY So, ... Cell reports 31 (9), 107725, 2020 | 450 | 2020 |
Limiting Cholesterol Biosynthetic Flux Spontaneously Engages Type I IFN Signaling AG York, KJ Williams, JP Argus, QD Zhou, G Brar, L Vergnes, EE Gray, ... Cell 163 (7), 1716-1729, 2015 | 386 | 2015 |
Serological assays for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), March 2020 RAPM Perera, CKP Mok, OTY Tsang, H Lv, RLW Ko, NC Wu, M Yuan, ... Eurosurveillance 25 (16), 2000421, 2020 | 382 | 2020 |
Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants M Yuan, D Huang, CCD Lee, NC Wu, AM Jackson, X Zhu, H Liu, L Peng, ... Science 373 (6556), 818-823, 2021 | 357 | 2021 |
Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape PA Koenig, H Das, H Liu, BM Kümmerer, FN Gohr, LM Jenster, ... Science 371 (6530), eabe6230, 2021 | 339 | 2021 |
A therapeutic non-self-reactive SARS-CoV-2 antibody protects from lung pathology in a COVID-19 hamster model J Kreye, SM Reincke, HC Kornau, E Sánchez-Sendin, VM Corman, H Liu, ... Cell 183 (4), 1058-1069. e19, 2020 | 331 | 2020 |
A comprehensive biophysical description of pairwise epistasis throughout an entire protein domain CA Olson, NC Wu, R Sun Current Biology 24 (22), 2643-2651, 2014 | 331 | 2014 |
A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine. NC Wu, SJ Zost, AJ Thompson, D Oyen, CM Nycholat, R McBride, ... PLoS pathogens 13 (10), e1006682, 2017 | 243 | 2017 |
A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic β-Hairpin Structure JH Lee, R Andrabi, CY Su, A Yasmeen, JP Julien, L Kong, NC Wu, ... Immunity 46 (4), 690-702, 2017 | 238 | 2017 |
Adaptation in protein fitness landscapes is facilitated by indirect paths NC Wu, L Dai, CA Olson, JO Lloyd-Smith, R Sun eLife 5, e16965, 2016 | 233 | 2016 |
Cross-neutralization of a SARS-CoV-2 antibody to a functionally conserved site is mediated by avidity H Liu, NC Wu, M Yuan, S Bangaru, JL Torres, TG Caniels, ... Immunity 53 (6), 1272-1280. e5, 2020 | 211 | 2020 |
Recognition of the SARS-CoV-2 receptor binding domain by neutralizing antibodies M Yuan, H Liu, NC Wu, IA Wilson Biochemical and Biophysical Research Communications 538, 192-203, 2021 | 180 | 2021 |
Deep mutational scanning of hemagglutinin helps predict evolutionary fates of human H3N2 influenza variants JM Lee, J Huddleston, MB Doud, KA Hooper, NC Wu, T Bedford, ... Proceedings of the National Academy of Sciences 115 (35), E8276-E8285, 2018 | 175 | 2018 |
An alternative binding mode of IGHV3-53 antibodies to the SARS-CoV-2 receptor binding domain NC Wu, M Yuan, H Liu, CCD Lee, X Zhu, S Bangaru, JL Torres, ... Cell reports 33 (3), 108274, 2020 | 155 | 2020 |
A perspective on the structural and functional constraints for immune evasion: Insights from influenza virus NC Wu, IA Wilson Journal of Molecular Biology 429 (17), 2694-2709, 2017 | 152 | 2017 |
Chromosomal DNA deletion confers phage resistance to Pseudomonas aeruginosa S Le, X Yao, S Lu, Y Tan, X Rao, M Li, X Jin, J Wang, Y Zhao, NC Wu, ... Scientific reports 4, 4738, 2014 | 123 | 2014 |
Influenza hemagglutinin structures and antibody recognition NC Wu, IA Wilson Cold Spring Harbor perspectives in medicine 10 (8), a038778, 2020 | 119 | 2020 |