Elevated free fatty acid uptake via CD36 promotes epithelial-mesenchymal transition in hepatocellular carcinoma A Nath, I Li, LR Roberts, C Chan Scientific reports 5 (1), 1-19, 2015 | 296 | 2015 |
Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen MP Menden, D Wang, MJ Mason, B Szalai, KC Bulusu, Y Guan, T Yu, ... Nature communications 10 (1), 2674, 2019 | 270 | 2019 |
Genetic alterations in fatty acid transport and metabolism genes are associated with metastatic progression and poor prognosis of human cancers A Nath, C Chan Scientific reports 6 (1), 18669, 2016 | 180 | 2016 |
Discovering novel pharmacogenomic biomarkers by imputing drug response in cancer patients from large genomics studies P Geeleher, Z Zhang, F Wang, RF Gruener, A Nath, G Morrison, S Bhutra, ... Genome research 27 (10), 1743-1751, 2017 | 102 | 2017 |
Rapid fine conformational epitope mapping using comprehensive mutagenesis and deep sequencing CA Kowalsky, MS Faber, A Nath, HE Dann, VW Kelly, L Liu, P Shanker, ... Journal of Biological Chemistry 290 (44), 26457-26470, 2015 | 88 | 2015 |
The double-stranded rna–dependent protein kinase differentially regulates insulin receptor substrates 1 and 2 in hepg2 cells X Yang, A Nath, MJ Opperman, C Chan Molecular biology of the cell 21 (19), 3449-3458, 2010 | 61 | 2010 |
Signaling dynamics of palmitate-induced ER stress responses mediated by ATF4 in HepG2 cells H Cho, M Wu, L Zhang, R Thompson, A Nath, C Chan BMC systems biology 7, 1-13, 2013 | 56 | 2013 |
Discovering long noncoding RNA predictors of anticancer drug sensitivity beyond protein-coding genes A Nath, EYT Lau, AM Lee, P Geeleher, WCS Cho, RS Huang Proceedings of the National Academy of Sciences 116 (44), 22020-22029, 2019 | 34 | 2019 |
Cancer expression quantitative trait loci (eQTLs) can be determined from heterogeneous tumor gene expression data by modeling variation in tumor purity P Geeleher, A Nath, F Wang, Z Zhang, AN Barbeira, J Fessler, ... Genome biology 19, 1-14, 2018 | 32 | 2018 |
Evolution of core archetypal phenotypes in progressive high grade serous ovarian cancer A Nath, PA Cosgrove, H Mirsafian, EL Christie, L Pflieger, B Copeland, ... Nature communications 12 (1), 3039, 2021 | 28 | 2021 |
Exploiting collateral sensitivity controls growth of mixed culture of sensitive and resistant cells and decreases selection for resistant cells in a cell line model VK Grolmusz, J Chen, R Emond, PA Cosgrove, L Pflieger, A Nath, ... Cancer cell international 20, 1-13, 2020 | 21 | 2020 |
Leveraging single-cell approaches in cancer precision medicine A Nath, AH Bild Trends in cancer 7 (4), 359-372, 2021 | 18 | 2021 |
Pharmacogenetics and pharmacogenomics of targeted therapeutics in chronic myeloid leukemia A Nath, J Wang, R Stephanie Huang Molecular diagnosis & therapy 21 (6), 621-631, 2017 | 18 | 2017 |
Long Non-Coding RNA ANRIL as a Potential Biomarker of Chemosensitivity and Clinical Outcomes in Osteosarcoma AM Lee, A Ferdjallah, E Moore, DC Kim, A Nath, E Greengard, RS Huang International journal of molecular sciences 22 (20), 11168, 2021 | 16 | 2021 |
Palmitate-Induced IRE1–XBP1–ZEB Signaling Represses Desmoplakin Expression and Promotes Cancer Cell Migration A Nath, A Oak, KY Chen, I Li, RC Splichal, J Portis, S Foster, SP Walton, ... Molecular Cancer Research 19 (2), 240-248, 2021 | 12 | 2021 |
Ensemble classification of cancer types and biomarker identification H Hijazi, M Wu, A Nath, C Chan Drug development research 73 (7), 414, 2012 | 12 | 2012 |
Clinical evaluation of germline polymorphisms associated with capecitabine toxicity in breast cancer: TBCRC-015 PH O’Donnell, V Trubetskoy, A Nurhussein-Patterson, JP Hall, A Nath, ... Breast Cancer Research and Treatment 181, 623-633, 2020 | 11 | 2020 |
Synergy analysis reveals association between insulin signaling and desmoplakin expression in palmitate treated HepG2 cells X Wang, A Nath, X Yang, A Portis, SP Walton, C Chan PloS one 6 (11), e28138, 2011 | 10 | 2011 |
Aone-two punch'therapy strategy to target chemoresistance in estrogen receptor positive breast cancer F Chi, J Liu, SW Brady, PA Cosgrove, A Nath, JA McQuerry, S Majumdar, ... Translational Oncology 14 (1), 100946, 2021 | 8 | 2021 |
Ecological interactions in breast cancer: Cell facilitation promotes growth and survival under drug pressure R Emond, JI Griffiths, VK Grolmusz, A Nath, J Chen, EF Medina, ... | 7 | 2021 |