Loss of mXinα, an intercalated disk protein, results in cardiac hypertrophy and cardiomyopathy with conduction defects EA Gustafson-Wagner, HW Sinn, YL Chen, DZ Wang, RS Reiter, JLC Lin, ... American Journal of Physiology-Heart and Circulatory Physiology 293 (5 …, 2007 | 81 | 2007 |
Defective retinal depolarizing bipolar cells in regulators of G protein signaling (RGS) 7 and 11 double null mice H Shim, CT Wang, YL Chen, VQ Chau, KG Fu, J Yang, AR McQuiston, ... Journal of Biological Chemistry 287 (18), 14873-14879, 2012 | 59 | 2012 |
Modulation of mouse rod response decay by rhodopsin kinase and recoverin CK Chen, ML Woodruff, FS Chen, Y Chen, MC Cilluffo, D Tranchina, ... Journal of Neuroscience 32 (45), 15998-16006, 2012 | 56 | 2012 |
Caveolar peroxynitrite formation impairs endothelial TRPV4 channels and elevates pulmonary arterial pressure in pulmonary hypertension Z Daneva, C Marziano, M Ottolini, YL Chen, TM Baker, M Kuppusamy, ... Proceedings of the National Academy of Sciences 118 (17), e2023130118, 2021 | 54 | 2021 |
Endothelial TRPV4 channels and vasodilator reactivity YL Chen, SK Sonkusare Current topics in membranes 85, 89-117, 2020 | 43 | 2020 |
Mechanisms underlying selective coupling of endothelial Ca2+ signals with eNOS vs. IK/SK channels in systemic and pulmonary arteries M Ottolini, Z Daneva, YL Chen, EL Cope, RB Kasetti, GS Zode, ... The Journal of physiology 598 (17), 3577-3596, 2020 | 42 | 2020 |
Impaired TRPV4-eNOS signaling in trabecular meshwork elevates intraocular pressure in glaucoma PD Patel, YL Chen, RB Kasetti, P Maddineni, W Mayhew, JC Millar, ... Proceedings of the National Academy of Sciences 118 (16), e2022461118, 2021 | 35 | 2021 |
A venous-specific purinergic signaling cascade initiated by Pannexin 1 regulates TNFα-induced increases in endothelial permeability D Maier-Begandt, HS Comstra, SA Molina, N Krüger, CA Ruddiman, ... Science signaling 14 (672), eaba2940, 2021 | 35 | 2021 |
Novel Smooth Muscle Ca2+-Signaling Nanodomains in Blood Pressure Regulation YL Chen, Z Daneva, M Kuppusamy, M Ottolini, TM Baker, E Klimentova, ... Circulation 146 (7), 548-564, 2022 | 32 | 2022 |
Endothelial pannexin 1–TRPV4 channel signaling lowers pulmonary arterial pressure in mice Z Daneva, M Ottolini, YL Chen, E Klimentova, M Kuppusamy, SA Shah, ... Elife 10, e67777, 2021 | 32 | 2021 |
Constriction of retinal venules to endothelin-1: obligatory roles of ETA receptors, extracellular calcium entry, and Rho kinase YL Chen, Y Ren, W Xu, RH Rosa, L Kuo, TW Hein Investigative ophthalmology & visual science 59 (12), 5167-5175, 2018 | 31 | 2018 |
On the mechanisms of arrhythmias in the myocardium of mXinα-deficient murine left atrial-pulmonary veins YJ Lai, EYK Huang, HI Yeh, YL Chen, JJC Lin, CI Lin Life sciences 83 (7-8), 272-283, 2008 | 19 | 2008 |
NEAP/DUSP26 suppresses receptor tyrosine kinases and regulates neuronal development in zebrafish CH Yang, YJ Yeh, JY Wang, YW Liu, YL Chen, HW Cheng, CM Cheng, ... Scientific reports 7 (1), 5241, 2017 | 17 | 2017 |
Hyperglycemia enhances constriction of retinal venules via activation of the reverse-mode sodium-calcium exchanger YL Chen, W Xu, RH Rosa Jr, L Kuo, TW Hein Diabetes 68 (8), 1624-1634, 2019 | 13 | 2019 |
Calcium signal profiles in vascular endothelium from Cdh5-GCaMP8 and Cx40-GCaMP2 mice YL Chen, TM Baker, F Lee, B Shui, JC Lee, P Tvrdik, MI Kotlikoff, ... Journal of vascular research 58 (3), 159-171, 2021 | 11 | 2021 |
Hyperglycemia augments endothelin-1–induced constriction of human retinal venules YL Chen, RH Rosa, L Kuo, TW Hein Translational Vision Science & Technology 9 (9), 1-1, 2020 | 8 | 2020 |
The polyanionic drug suramin neutralizes histones and prevents endotheliopathy N Villalba, AM Sackheim, MA Lawson, L Haines, YL Chen, SK Sonkusare, ... The Journal of Immunology 211 (4), 648-657, 2023 | 5 | 2023 |
Purinergic P2Y2 receptor–induced activation of endothelial TRPV4 channels mediates lung ischemia-reperfusion injury M Kuppusamy, HQ Ta, HN Davenport, A Bazaz, A Kulshrestha, Z Daneva, ... Science signaling 16 (808), eadg1553, 2023 | 4 | 2023 |
Endothelial IK and SK channel activation decreases pulmonary arterial pressure and vascular remodeling in pulmonary hypertension Z Daneva, YL Chen, HQ Ta, V Manchikalapudi, A Bazaz, VE Laubach, ... Pulmonary Circulation 13 (1), e12186, 2023 | 4 | 2023 |
Contributions of sodium-hydrogen exchanger 1 and mitogen-activated protein kinases to enhanced retinal venular constriction to endothelin-1 in diabetes YL Chen, Y Ren, RH Rosa Jr, L Kuo, TW Hein Diabetes 70 (10), 2353-2363, 2021 | 4 | 2021 |