Apolipoprotein E structure: insights into function DM Hatters, CA Peters-Libeu, KH Weisgraber Trends in biochemical sciences 31 (8), 445-454, 2006 | 721 | 2006 |
Structural and functional analysis of a plant resistance protein TIR domain reveals interfaces for self-association, signaling, and autoregulation M Bernoux, T Ve, S Williams, C Warren, D Hatters, E Valkov, X Zhang, ... Cell host & microbe 9 (3), 200-211, 2011 | 393 | 2011 |
Prion-like domains in RNA binding proteins are essential for building subnuclear paraspeckles S Hennig, G Kong, T Mannen, A Sadowska, S Kobelke, A Blythe, GJ Knott, ... Journal of Cell Biology 210 (4), 529-539, 2015 | 318 | 2015 |
Macromolecular crowding accelerates amyloid formation by human apolipoprotein C-II DM Hatters, AP Minton, GJ Howlett Journal of Biological Chemistry 277 (10), 7824-7830, 2002 | 297 | 2002 |
Apolipoprotein E4 forms a molten globule: a potential basis for its association with disease JA Morrow, DM Hatters, B Lu, P Höchtl, KA Oberg, B Rupp, ... Journal of Biological Chemistry 277 (52), 50380-50385, 2002 | 250 | 2002 |
Identifying polyglutamine protein species in situ that best predict neurodegeneration J Miller, M Arrasate, E Brooks, CP Libeu, J Legleiter, D Hatters, J Curtis, ... Nature chemical biology 7 (12), 925-934, 2011 | 239 | 2011 |
Walking the tightrope: proteostasis and neurodegenerative disease JJ Yerbury, L Ooi, A Dillin, DN Saunders, DM Hatters, PM Beart, ... Journal of neurochemistry 137 (4), 489-505, 2016 | 217 | 2016 |
Fibrillar amyloid protein present in atheroma activates CD36 signal transduction LA Medeiros, T Khan, JB El Khoury, CLL Pham, DM Hatters, GJ Howlett, ... Journal of Biological Chemistry 279 (11), 10643-10648, 2004 | 169 | 2004 |
Human apolipoprotein C-II forms twisted amyloid ribbons and closed loops DM Hatters, CE MacPhee, LJ Lawrence, WH Sawyer, GJ Howlett Biochemistry 39 (28), 8276-8283, 2000 | 152 | 2000 |
Distinct partitioning of ALS associated TDP-43, FUS and SOD1 mutants into cellular inclusions NE Farrawell, IA Lambert-Smith, ST Warraich, IP Blair, DN Saunders, ... Scientific reports 5 (1), 13416, 2015 | 145 | 2015 |
A thiol probe for measuring unfolded protein load and proteostasis in cells MZ Chen, NS Moily, JL Bridgford, RJ Wood, M Radwan, TA Smith, Z Song, ... Nature communications 8 (1), 1-11, 2017 | 143 | 2017 |
Tracking mutant huntingtin aggregation kinetics in cells reveals three major populations that include an invariant oligomer pool MA Olshina, LM Angley, YM Ramdzan, J Tang, MF Bailey, AF Hill, ... Journal of Biological Chemistry 285 (28), 21807-21816, 2010 | 140 | 2010 |
The molecular chaperone, α-crystallin, inhibits amyloid formation by apolipoprotein C-II DM Hatters, RA Lindner, JA Carver, GJ Howlett Journal of Biological Chemistry 276 (36), 33755-33761, 2001 | 125 | 2001 |
Tracking protein aggregation and mislocalization in cells with flow cytometry YM Ramdzan, S Polling, CPZ Chia, IHW Ng, AR Ormsby, NP Croft, ... Nature methods 9 (5), 467-470, 2012 | 123 | 2012 |
Amino-terminal domain stability mediates apolipoprotein E aggregation into neurotoxic fibrils DM Hatters, N Zhong, E Rutenber, KH Weisgraber Journal of molecular biology 361 (5), 932-944, 2006 | 120 | 2006 |
Model of biologically active apolipoprotein E bound to dipalmitoylphosphatidylcholine CA Peters-Libeu, Y Newhouse, DM Hatters, KH Weisgraber Journal of Biological Chemistry 281 (2), 1073-1079, 2006 | 112 | 2006 |
Huntingtin inclusions trigger cellular quiescence, deactivate apoptosis, and lead to delayed necrosis YM Ramdzan, MM Trubetskov, AR Ormsby, EA Newcombe, X Sui, ... Cell reports 19 (5), 919-927, 2017 | 110 | 2017 |
The structural basis for amyloid formation by plasma apolipoproteins: a review DM Hatters, GJ Howlett European Biophysics Journal 31, 2-8, 2002 | 106 | 2002 |
Modulation of apolipoprotein E structure by domain interaction: differences in lipid-bound and lipid-free forms DM Hatters, MS Budamagunta, JC Voss, KH Weisgraber Journal of Biological Chemistry 280 (40), 34288-34295, 2005 | 102 | 2005 |
NMR structure of human apolipoprotein C-II in the presence of sodium dodecyl sulfate CA MacRaild, DM Hatters, GJ Howlett, PR Gooley Biochemistry 40 (18), 5414-5421, 2001 | 88 | 2001 |