Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression A Yokoyama, Z Wang, J Wysocka, M Sanyal, DJ Aufiero, I Kitabayashi, ... Molecular and cellular biology, 2004 | 787 | 2004 |
The menin tumor suppressor protein is an essential oncogenic cofactor for MLL-associated leukemogenesis A Yokoyama, TCP Somervaille, KS Smith, O Rozenblatt-Rosen, ... Cell 123 (2), 207-218, 2005 | 660 | 2005 |
Menin critically links MLL proteins with LEDGF on cancer-associated target genes A Yokoyama, ML Cleary Cancer cell 14 (1), 36-46, 2008 | 572 | 2008 |
Interaction and functional cooperation of the leukemia‐associated factors AML1 and p300 in myeloid cell differentiation I Kitabayashi, A Yokoyama, K Shimizu, M Ohki The EMBO journal, 1998 | 416 | 1998 |
A higher-order complex containing AF4 and ENL family proteins with P-TEFb facilitates oncogenic and physiologic MLL-dependent transcription A Yokoyama, M Lin, A Naresh, I Kitabayashi, ML Cleary Cancer cell 17 (2), 198-212, 2010 | 403 | 2010 |
Activation of AML1‐mediated transcription by MOZ and inhibition by the MOZ–CBP fusion protein I Kitabayashi, Y Aikawa, LA Nguyen, A Yokoyama, M Ohki The EMBO journal, 2001 | 273 | 2001 |
Leukemia proto-oncoprotein MLL is proteolytically processed into 2 fragments with opposite transcriptional properties A Yokoyama, I Kitabayashi, PM Ayton, ML Cleary, M Ohki Blood, The Journal of the American Society of Hematology 100 (10), 3710-3718, 2002 | 203 | 2002 |
Fusion of MOZ and p300 histone acetyltransferases in acute monocytic leukemia with at (8; 22)(p11; q13) chromosome translocation I Kitabayashi, Y Aikawa, A Yokoyama, F Hosoda, M Nagai, N Kakazu, ... Leukemia 15 (1), 89-94, 2001 | 185 | 2001 |
The AML1-MTG8 leukemic fusion protein forms a complex with a novel member of the MTG8 (ETO/CDR) family, MTGR1 I Kitabayashi, K Ida, F Morohoshi, A Yokoyama, N Mitsuhashi, K Shimizu, ... Molecular and cellular biology 18 (2), 846-858, 1998 | 185 | 1998 |
Mutant ASXL1 cooperates with BAP1 to promote myeloid leukaemogenesis S Asada, S Goyama, D Inoue, S Shikata, R Takeda, T Fukushima, ... Nature communications 9 (1), 2733, 2018 | 114 | 2018 |
Interaction of Epstein-Barr virus nuclear antigen leader protein (EBNA-LP) with HS1-associated protein X-1: implication of cytoplasmic function of EBNA-LP Y Kawaguchi, K Nakajima, M Igarashi, T Morita, M Tanaka, M Suzuki, ... Journal of virology 74 (21), 10104-10111, 2000 | 111 | 2000 |
Herpes simplex virus 1 α regulatory protein ICP0 functionally interacts with cellular transcription factor BMAL1 Y Kawaguchi, M Tanaka, A Yokoymama, G Matsuda, K Kato, H Kagawa, ... Proceedings of the National Academy of Sciences 98 (4), 1877-1882, 2001 | 99 | 2001 |
MLL2, not MLL1, plays a major role in sustaining MLL-rearranged acute myeloid leukemia Y Chen, K Anastassiadis, A Kranz, AF Stewart, K Arndt, C Waskow, ... Cancer cell 31 (6), 755-770. e6, 2017 | 93 | 2017 |
Epstein–Barr virus-encoded protein kinase BGLF4 mediates hyperphosphorylation of cellular elongation factor 1δ (EF-1δ): EF-1δ is universally modified by conserved protein … K Kato, Y Kawaguchi, M Tanaka, M Igarashi, A Yokoyama, G Matsuda, ... Journal of General Virology 82 (6), 1457-1463, 2001 | 81 | 2001 |
Identification of protein kinases responsible for phosphorylation of Epstein–Barr virus nuclear antigen leader protein at serine-35, which regulates its coactivator function K Kato, A Yokoyama, Y Tohya, H Akashi, Y Nishiyama, Y Kawaguchi Journal of general virology 84 (12), 3381-3392, 2003 | 75 | 2003 |
Identification of major phosphorylation sites of Epstein-Barr virus nuclear antigen leader protein (EBNA-LP): ability of EBNA-LP to induce latent membrane protein 1 … A Yokoyama, M Tanaka, G Matsuda, K Kato, M Kanamori, H Kawasaki, ... Journal of virology 75 (11), 5119-5128, 2001 | 73 | 2001 |
Combined Cohesin–RUNX1 deficiency synergistically perturbs chromatin looping and causes myelodysplastic syndromes Y Ochi, A Kon, T Sakata, MM Nakagawa, N Nakazawa, M Kakuta, ... Cancer discovery 10 (6), 836-853, 2020 | 66 | 2020 |
A novel ASXL1–OGT axis plays roles in H3K4 methylation and tumor suppression in myeloid malignancies D Inoue, T Fujino, P Sheridan, Y Zhang, R Nagase, S Horikawa, Z Li, ... Leukemia 32 (6), 1327-1337, 2018 | 65 | 2018 |
Cooperative gene activation by AF4 and DOT1L drives MLL-rearranged leukemia H Okuda, B Stanojevic, A Kanai, T Kawamura, S Takahashi, H Matsui, ... The Journal of clinical investigation 127 (5), 1918-1931, 2017 | 63 | 2017 |
Biological implications of somatic DDX41 p. R525H mutation in acute myeloid leukemia M Kadono, A Kanai, A Nagamachi, S Shinriki, J Kawata, K Iwato, T Kyo, ... Experimental Hematology 44 (8), 745-754. e4, 2016 | 61 | 2016 |