Design and production of bispecific antibodies Q Wang, Y Chen, J Park, X Liu, Y Hu, T Wang, K McFarland, ... Antibodies 8 (3), 43, 2019 | 221 | 2019 |
An unconventional uptake rate objective function approach enhances applicability of genome-scale models for mammalian cells Y Chen, BO McConnell, V Gayatri Dhara, H Mukesh Naik, CT Li, ... NPJ systems biology and applications 5 (1), 25, 2019 | 44 | 2019 |
Utilizing genome-scale models to optimize nutrient supply for sustained algal growth and lipid productivity CT Li, J Yelsky, Y Chen, C Zuñiga, R Eng, L Jiang, A Shapiro, KW Huang, ... NPJ systems biology and applications 5 (1), 33, 2019 | 29 | 2019 |
Combining butyrated ManNAc with glycoengineered CHO cells improves EPO glycan quality and production Q Wang, CY Chung, W Yang, G Yang, S Chough, Y Chen, B Yin, ... Biotechnology Journal 14 (4), 1800186, 2019 | 26 | 2019 |
A linkage-specific sialic acid Labeling strategy reveals different site-specific glycosylation patterns in SARS-CoV-2 spike protein produced in CHO and HEK cell substrates Q Wang, Y Wang, S Yang, C Lin, L Aliyu, Y Chen, L Parsons, Y Tian, H Jia, ... Frontiers in Chemistry 9, 735558, 2021 | 15 | 2021 |
Metabolic engineering challenges of extending N-glycan pathways in Chinese hamster ovary cells Q Wang, T Wang, S Yang, S Sha, WW Wu, Y Chen, JT Paul, RF Shen, ... Metabolic Engineering 61, 301-314, 2020 | 10 | 2020 |
A genome‐scale nutrient minimization forecast algorithm for controlling essential amino acid levels in CHO cell cultures Y Chen, X Liu, JYL Anderson, HM Naik, VG Dhara, X Chen, GA Harris, ... Biotechnology and Bioengineering 119 (2), 435-451, 2022 | 5 | 2022 |
Optimization of nutrient utilization efficiency and productivity for algal cultures under light and dark cycles using genome-scale model process control CT Li, R Eng, C Zuniga, KW Huang, Y Chen, K Zengler, MJ Betenbaugh npj Systems Biology and Applications 9 (1), 7, 2023 | 4 | 2023 |
Reconstruction of reverse transsulfuration pathway enables cysteine biosynthesis and enhances resilience to oxidative stress in Chinese Hamster Ovary cells Y Chen, MJ Betenbaugh Metabolic Engineering 76, 204-214, 2023 | 2 | 2023 |
Three doses of COVID-19 mRNA vaccine induce class-switched antibody responses in inflammatory arthritis patients on immunomodulatory therapies JM Lee, A Figueroa, J Sachithanandham, M Li, CM Connolly, JR Shapiro, ... Frontiers in immunology 14, 1266370, 2023 | | 2023 |
Constraint-based modeling and genome-scale metabolic models to understand metabolism of Chinese hamster ovary cells Y Chen, M Betenbaugh ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019 | | 2019 |
Applying metabolic models for control in order to enhance algal growth and lipid production CT Li, Y Chen, R Eng, M Betenbaugh, C Zuñiga, K Zengler | | 2019 |
Towards a universal CHO reference platform with epigenome characterization for the biotechnology community M Betenbaugh, Y Chen, HM Naik, V Gayatri Dhara, D Nmagu, J Baik, ... | | 2018 |