Proteopathic tau seeding predicts tauopathy in vivo BB Holmes, JL Furman, TE Mahan, TR Yamasaki, H Mirbaha, WC Eades, ... Proceedings of the National Academy of sciences 111 (41), E4376-E4385, 2014 | 597 | 2014 |
Cognitive decline in Alzheimer's disease is associated with selective changes in calcineurin/NFAT signaling HM Abdul, MA Sama, JL Furman, DM Mathis, TL Beckett, AM Weidner, ... Journal of Neuroscience 29 (41), 12957-12969, 2009 | 337 | 2009 |
Targeting astrocytes ameliorates neurologic changes in a mouse model of Alzheimer's disease JL Furman, DM Sama, JC Gant, TL Beckett, MP Murphy, AD Bachstetter, ... Journal of Neuroscience 32 (46), 16129-16140, 2012 | 330 | 2012 |
Parkinson’s disease and multiple system atrophy have distinct α-synuclein seed characteristics TR Yamasaki, BB Holmes, JL Furman, DD Dhavale, BW Su, ES Song, ... Journal of Biological Chemistry 294 (3), 1045-1058, 2019 | 176 | 2019 |
Peripheral biomarkers of major depression and antidepressant treatment response: current knowledge and future outlooks BS Gadad, MK Jha, A Czysz, JL Furman, TL Mayes, MP Emslie, ... Journal of affective disorders 233, 3-14, 2018 | 159 | 2018 |
Interleukin-1β-dependent signaling between astrocytes and neurons depends critically on astrocytic calcineurin/NFAT activity MA Sama, DM Mathis, JL Furman, HM Abdul, IA Artiushin, SD Kraner, ... Journal of Biological Chemistry 283 (32), 21953-21964, 2008 | 156 | 2008 |
Ultrasensitive and selective detection of 3-repeat tau seeding activity in Pick disease brain and cerebrospinal fluid E Saijo, B Ghetti, G Zanusso, A Oblak, JL Furman, MI Diamond, A Kraus, ... Acta neuropathologica 133, 751-765, 2017 | 143 | 2017 |
Widespread tau seeding activity at early Braak stages JL Furman, J Vaquer-Alicea, CL White, NJ Cairns, PT Nelson, ... Acta neuropathologica 133, 91-100, 2017 | 139 | 2017 |
Calcineurin and glial signaling: neuroinflammation and beyond JL Furman, CM Norris Journal of neuroinflammation 11, 1-12, 2014 | 110 | 2014 |
Preparation of acute hippocampal slices from rats and transgenic mice for the study of synaptic alterations during aging and amyloid pathology DM Mathis, JL Furman, CM Norris JoVE (Journal of Visualized Experiments), e2330, 2011 | 97 | 2011 |
Calcineurin/NFAT signaling in activated astrocytes drives network hyperexcitability in Aβ-bearing mice P Sompol, JL Furman, MM Pleiss, SD Kraner, IA Artiushin, SR Batten, ... Journal of Neuroscience 37 (25), 6132-6148, 2017 | 96 | 2017 |
Blockade of astrocytic calcineurin/NFAT signaling helps to normalize hippocampal synaptic function and plasticity in a rat model of traumatic brain injury JL Furman, P Sompol, SD Kraner, MM Pleiss, EJ Putman, J Dunkerson, ... Journal of Neuroscience 36 (5), 1502-1515, 2016 | 85 | 2016 |
Sensitive detection of proteopathic seeding activity with FRET flow cytometry JL Furman, BB Holmes, MI Diamond JoVE (Journal of Visualized Experiments), e53205, 2015 | 82 | 2015 |
NFATs and Alzheimer’s disease HM Abdul, JL Furman, MA Sama, DM Mathis, CM Norris Molecular and Cellular Pharmacology 2 (1), 7, 2010 | 70 | 2010 |
Expression of SORL1 and a novel SORL1 splice variant in normal and Alzheimers disease brain KE Grear, IF Ling, JF Simpson, JL Furman, CR Simmons, SL Peterson, ... Molecular neurodegeneration 4, 1-13, 2009 | 70 | 2009 |
Inhibition of Soluble Tumor Necrosis Factor Ameliorates Synaptic Alterations and Ca2+ Dysregulation in Aged Rats DM Sama, H Mohmmad Abdul, JL Furman, IA Artiushin, DE Szymkowski, ... PloS one 7 (5), e38170, 2012 | 63 | 2012 |
Calcineurin proteolysis in astrocytes: implications for impaired synaptic function MM Pleiss, P Sompol, SD Kraner, HM Abdul, JL Furman, RP Guttmann, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1862 (9 …, 2016 | 43 | 2016 |
Early engineering approaches to improve peptide developability and manufacturability JL Furman, M Chiu, MJ Hunter The AAPS journal 17, 111-120, 2015 | 42 | 2015 |
Childhood maltreatment and impact on clinical features of major depression in adults GC Medeiros, WL Prueitt, A Minhajuddin, SS Patel, AH Czysz, JL Furman, ... Psychiatry research 293, 113412, 2020 | 35 | 2020 |
Evaluation of the benefits of exercise on cognition in major depressive disorder TL Greer, JL Furman, MH Trivedi General hospital psychiatry 49, 19-25, 2017 | 32 | 2017 |