Enhanced autophagy ameliorates cardiac proteinopathy MS Bhuiyan, JS Pattison, H Osinska, J James, J Gulick, PM McLendon, ... The Journal of clinical investigation 123 (12), 5284-5297, 2013 | 303 | 2013 |
Desmin-related cardiomyopathy: an unfolding story PM McLendon, J Robbins American Journal of Physiology-Heart and Circulatory Physiology 301 (4 …, 2011 | 157 | 2011 |
Tubulin hyperacetylation is adaptive in cardiac proteotoxicity by promoting autophagy PM McLendon, BS Ferguson, H Osinska, MS Bhuiyan, J James, ... Proceedings of the National Academy of Sciences 111 (48), E5178-E5186, 2014 | 120 | 2014 |
Poly (glycoamidoamine) vehicles promote pDNA uptake through multiple routes and efficient gene expression via caveolae-mediated endocytosis PM McLendon, KM Fichter, TM Reineke Molecular pharmaceutics 7 (3), 738-750, 2010 | 111 | 2010 |
Polymer beacons for luminescence and magnetic resonance imaging of DNA delivery JM Bryson, KM Fichter, WJ Chu, JH Lee, J Li, LA Madsen, PM McLendon, ... Proceedings of the National Academy of Sciences 106 (40), 16913-16918, 2009 | 108 | 2009 |
Proteotoxicity and cardiac dysfunction PM McLendon, J Robbins Circulation research 116 (11), 1863-1882, 2015 | 96 | 2015 |
Polymeric nucleic acid vehicles exploit active interorganelle trafficking mechanisms KM Fichter, NP Ingle, PM McLendon, TM Reineke ACS nano 7 (1), 347-364, 2013 | 95 | 2013 |
UBC9-mediated sumoylation favorably impacts cardiac function in compromised hearts MK Gupta, PM McLendon, J Gulick, J James, K Khalili, J Robbins Circulation research 118 (12), 1894-1905, 2016 | 69 | 2016 |
Carbohydrate polymers for nonviral nucleic acid delivery A Sizovs, PM McLendon, S Srinivasachari, TM Reineke Nucleic Acid Transfection, 131-190, 2010 | 67 | 2010 |
Toward targeting RNA structure: Branched peptides as cell-permeable ligands to TAR RNA DI Bryson, W Zhang, PM McLendon, TM Reineke, WL Santos ACS Chemical Biology 7 (1), 210-217, 2012 | 58 | 2012 |
Interaction of poly (glycoamidoamine) DNA delivery vehicles with cell-surface glycosaminoglycans leads to polyplex internalization in a manner not solely dependent on charge PM McLendon, DJ Buckwalter, EM Davis, TM Reineke Molecular pharmaceutics 7 (5), 1757-1768, 2010 | 42 | 2010 |
Ube2v1 positively regulates protein aggregation by modulating ubiquitin proteasome system performance partially through K63 ubiquitination N Xu, J Gulick, H Osinska, Y Yu, PM McLendon, K Shay-Winkler, ... Circulation research 126 (7), 907-922, 2020 | 25 | 2020 |
In vivo definition of cardiac myosin-binding protein C’s critical interactions with myosin MS Bhuiyan, P McLendon, J James, H Osinska, J Gulick, B Bhandary, ... Pflügers Archiv-European Journal of Physiology 468 (10), 1685-1695, 2016 | 24 | 2016 |
A high-throughput screening identifies ZNF418 as a novel regulator of the ubiquitin-proteasome system and autophagy-lysosomal pathway SR Singh, M Meyer-Jens, E Alizoti, WC Bacon, G Davis, H Osinska, ... Autophagy 17 (10), 3124-3139, 2021 | 16 | 2021 |
An unbiased high-throughput screen to identify novel effectors that impact on cardiomyocyte aggregate levels PM McLendon, G Davis, J Gulick, SR Singh, N Xu, N Salomonis, ... Circulation research 121 (6), 604-616, 2017 | 16 | 2017 |
A Polycation Scaffold Presenting Tunable “Click” Sites: Conjugation to Carbohydrate Ligands and Examination of Hepatocyte‐Targeted pDNA Delivery CC Lee, G Grandinetti, PM McLendon, TM Reineke Macromolecular Bioscience 10 (6), 585-598, 2010 | 16 | 2010 |
Voluntary exercise and Atg7 overexpression induced autophagy ameliorates cardiac proteinopathy MS Bhuiyan, JS Pattison, H Osinska, J James, J Gulick, PM McLendon, ... Circulation 128 (suppl_22), A11097-A11097, 2013 | 5 | 2013 |
JAK1 Inhibitors reduce CRYABR120G aggregates in rat and human cardiomyocytes E Alizoti, L Michler, E Orthey, H Osinska, J Gulick, B Klampe, T Schulze, ... Journal of Molecular and Cellular Cardiology 173, S95-S96, 2022 | 1 | 2022 |
Ube2v1 Promotes Mutant αB-crystallin-induced Protein Aggregation N Xu, P McLendon, J Gulick, H Osinska, J Robbins Circulation Research 123 (Suppl_1), A238-A238, 2018 | | 2018 |
Screening modulators of the ubiquitin-proteasome system and the autophagy-lysosomal pathway-Towards novel targets to treat proteotoxicity SR Singh, WC Bacon, G Davis, J Gulick, H Osinska, P McLendon, ... JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 109, 23-23, 2017 | | 2017 |