Strategies and challenges for the next generation of antibody–drug conjugates A Beck, L Goetsch, C Dumontet, N Corvaïa Nature reviews Drug discovery 16 (5), 315-337, 2017 | 1970 | 2017 |
Strategies and challenges for the next generation of therapeutic antibodies A Beck, T Wurch, C Bailly, N Corvaia Nature reviews immunology 10 (5), 345-352, 2010 | 1075 | 2010 |
Characterization of therapeutic antibodies and related products A Beck, E Wagner-Rousset, D Ayoub, A Van Dorsselaer, ... Analytical chemistry 85 (2), 715-736, 2013 | 673 | 2013 |
Theory and practice of size exclusion chromatography for the analysis of protein aggregates S Fekete, A Beck, JL Veuthey, D Guillarme Journal of pharmaceutical and biomedical analysis 101, 161-173, 2014 | 370 | 2014 |
Trends in glycosylation, glycoanalysis and glycoengineering of therapeutic antibodies and Fc-fusion proteins A Beck, E Wagner-Rousset, MC Bussat, M Lokteff, C Klinguer-Hamour, ... Current pharmaceutical biotechnology 9 (6), 482-501, 2008 | 311 | 2008 |
Biosimilar, biobetter, and next generation antibody characterization by mass spectrometry A Beck, S Sanglier-Cianférani, A Van Dorsselaer Analytical chemistry 84 (11), 4637-4646, 2012 | 307 | 2012 |
Antibody–drug conjugates: The last decade N Joubert, A Beck, C Dumontet, C Denevault-Sabourin Pharmaceuticals 13 (9), 245, 2020 | 294 | 2020 |
Ion-exchange chromatography for the characterization of biopharmaceuticals S Fekete, A Beck, JL Veuthey, D Guillarme Journal of pharmaceutical and biomedical analysis 113, 43-55, 2015 | 284 | 2015 |
Identification and characterization of asparagine deamidation in the light chain CDR1 of a humanized IgG1 antibody J Vlasak, MC Bussat, S Wang, E Wagner-Rousset, M Schaefer, ... Analytical biochemistry 392 (2), 145-154, 2009 | 280 | 2009 |
A recombinant humanized anti‐insulin‐like growth factor receptor type I antibody (h7C10) enhances the antitumor activity of vinorelbine and anti‐epidermal growth factor … L Goetsch, A Gonzalez, O Leger, A Beck, PJ Pauwels, JF Haeuw, ... International journal of cancer 113 (2), 316-328, 2005 | 277 | 2005 |
Marketing approval of mogamulizumab: a triumph for glyco-engineering A Beck, JM Reichert MAbs 4 (4), 419-425, 2012 | 237 | 2012 |
Anti-IGF-IR antibodies and uses thereof L Goetsch, N Corvaia, O Leger, A Duflos, JF Haeuw, A Beck US Patent 7,241,444, 2007 | 224* | 2007 |
Structure, heterogeneity and developability assessment of therapeutic antibodies Y Xu, D Wang, B Mason, T Rossomando, N Li, D Liu, JK Cheung, W Xu, ... MAbs 11 (2), 239-264, 2019 | 218 | 2019 |
Middle-down analysis of monoclonal antibodies with electron transfer dissociation orbitrap fourier transform mass spectrometry L Fornelli, D Ayoub, K Aizikov, A Beck, YO Tsybin Analytical chemistry 86 (6), 3005-3012, 2014 | 212 | 2014 |
The next generation of antibody-drug conjugates comes of age A Beck, JF Haeuw, T Wurch, L Goetsch, C Bailly, N Corvaïa Discovery medicine 10 (53), 329-339, 2010 | 207 | 2010 |
Innovative native MS methodologies for antibody drug conjugate characterization: high resolution native MS and IM-MS for average DAR and DAR distribution assessment F Debaene, A Boeuf, E Wagner-Rousset, O Colas, D Ayoub, N Corvaia, ... Analytical chemistry 86 (21), 10674-10683, 2014 | 197 | 2014 |
Correct primary structure assessment and extensive glyco-profiling of cetuximab by a combination of intact, middle-up, middle-down and bottom-up ESI and MALDI mass spectrometry … D Ayoub, W Jabs, A Resemann, W Evers, C Evans, L Main, C Baessmann, ... MAbs 5 (5), 699-710, 2013 | 197 | 2013 |
Forced degradation of recombinant monoclonal antibodies: A practical guide C Nowak, J K. Cheung, S M. Dellatore, A Katiyar, R Bhat, J Sun, ... MAbs 9 (8), 1217-1230, 2017 | 194 | 2017 |
Therapeutic Fc-fusion proteins and peptides as successful alternatives to antibodies A Beck, JM Reichert MAbs 3 (5), 415-416, 2011 | 192 | 2011 |
Determination of isoelectric points and relative charge variants of 23 therapeutic monoclonal antibodies A Goyon, M Excoffier, MC Janin-Bussat, B Bobaly, S Fekete, D Guillarme, ... Journal of Chromatography B 1065, 119-128, 2017 | 188 | 2017 |