Hydrogen sulfide is an endogenous modulator of leukocyte‐mediated inflammation RCO Zanardo, V Brancaleone, E Distrutti, S Fiorucci, G Cirino, JL Wallace, ... The FASEB journal 20 (12), 2118-2120, 2006 | 1113 | 2006 |
6α-ethyl-chenodeoxycholic acid (6-ECDCA), a potent and selective FXR agonist endowed with anticholestatic activity R Pellicciari, S Fiorucci, E Camaioni, C Clerici, G Costantino, PR Maloney, ... Journal of medicinal chemistry 45 (17), 3569-3572, 2002 | 873 | 2002 |
The third gas: H2S regulates perfusion pressure in both the isolated and perfused normal rat liver and in cirrhosis S Fiorucci, E Antonelli, A Mencarelli, S Orlandi, B Renga, G Rizzo, ... Hepatology 42 (3), 539-548, 2005 | 640 | 2005 |
The bile acid receptor FXR is a modulator of intestinal innate immunity P Vavassori, A Mencarelli, B Renga, E Distrutti, S Fiorucci The Journal of Immunology 183 (10), 6251-6261, 2009 | 611 | 2009 |
Inhibition of hydrogen sulfide generation contributes to gastric injury caused by anti-inflammatory nonsteroidal drugs S Fiorucci, E Antonelli, E Distrutti, G Rizzo, A Mencarelli, S Orlandi, ... Gastroenterology 129 (4), 1210-1224, 2005 | 544 | 2005 |
The emerging roles of hydrogen sulfide in the gastrointestinal tract and liver S Fiorucci, E Distrutti, G Cirino, JL Wallace Gastroenterology 131 (1), 259-271, 2006 | 528 | 2006 |
The nuclear receptor SHP mediates inhibition of hepatic stellate cells by FXR and protects against liver fibrosis S Fiorucci, E Antonelli, G Rizzo, B Renga, A Mencarelli, L Riccardi, ... Gastroenterology 127 (5), 1497-1512, 2004 | 507 | 2004 |
Bile acid-activated receptors, intestinal microbiota, and the treatment of metabolic disorders S Fiorucci, E Distrutti Trends in molecular medicine 21 (11), 702-714, 2015 | 457 | 2015 |
FXR activation reverses insulin resistance and lipid abnormalities and protects against liver steatosis in Zucker (fa/fa) obese rats [S] S Cipriani, A Mencarelli, G Palladino, S Fiorucci Journal of lipid research 51 (4), 771-784, 2010 | 449 | 2010 |
Bile acids activated receptors regulate innate immunity S Fiorucci, M Biagioli, A Zampella, E Distrutti Frontiers in immunology 9, 1853, 2018 | 413 | 2018 |
Gut microbiota role in irritable bowel syndrome: New therapeutic strategies E Distrutti, L Monaldi, P Ricci, S Fiorucci World journal of gastroenterology 22 (7), 2219, 2016 | 397 | 2016 |
Dual inhibitors of cyclooxygenase and 5-lipoxygenase. A new avenue in anti-inflammatory therapy? S Fiorucci, R Meli, M Bucci, G Cirino Biochemical pharmacology 62 (11), 1433-1438, 2001 | 394 | 2001 |
Bile-acid-activated receptors: targeting TGR5 and farnesoid-X-receptor in lipid and glucose disorders S Fiorucci, A Mencarelli, G Palladino, S Cipriani Trends in pharmacological sciences 30 (11), 570-580, 2009 | 370 | 2009 |
The bile acid receptor GPBAR-1 (TGR5) modulates integrity of intestinal barrier and immune response to experimental colitis S Cipriani, A Mencarelli, MG Chini, E Distrutti, B Renga, G Bifulco, ... PloS one 6 (10), e25637, 2011 | 369 | 2011 |
Evidence that hydrogen sulfide exerts antinociceptive effects in the gastrointestinal tract by activating KATP channels E Distrutti, L Sediari, A Mencarelli, B Renga, S Orlandi, E Antonelli, ... Journal of Pharmacology and Experimental Therapeutics 316 (1), 325-335, 2006 | 338 | 2006 |
Gastrointestinal safety and anti-inflammatory effects of a hydrogen sulfide–releasing diclofenac derivative in the rat JL Wallace, G Caliendo, V Santagada, G Cirino, S Fiorucci Gastroenterology 132 (1), 261-271, 2007 | 335 | 2007 |
Galectin-1 suppresses experimental colitis in mice L Santucci, S Fiorucci, N Rubinstein, A Mencarelli, B Palazzetti, B Federici, ... Gastroenterology 124 (5), 1381-1394, 2003 | 318 | 2003 |
Gastrointestinal safety of NO-aspirin (NCX-4016) in healthy human volunteers: a proof of concept endoscopic study S Fiorucci, L Santucci, P Gresele, RM Faccino, P Del Soldato, A Morelli Gastroenterology 124 (3), 600-607, 2003 | 296 | 2003 |
Enhanced activity of a hydrogen sulphide‐releasing derivative of mesalamine (ATB‐429) in a mouse model of colitis S Fiorucci, S Orlandi, A Mencarelli, G Caliendo, V Santagada, E Distrutti, ... British journal of pharmacology 150 (8), 996-1002, 2007 | 263 | 2007 |
Bile acid derivatives as ligands of the farnesoid X receptor. Synthesis, evaluation, and structure− activity relationship of a series of body and side chain modified analogues … R Pellicciari, G Costantino, E Camaioni, BM Sadeghpour, A Entrena, ... Journal of medicinal chemistry 47 (18), 4559-4569, 2004 | 249 | 2004 |