| Pyroptosis is driven by non-selective gasdermin-D pore and its morphology is different from MLKL channel-mediated necroptosis X Chen, W He, L Hu, J Li, Y Fang, X Wang, X Xu, Z Wang, K Huang, J Han Cell research 26 (9), 1007-1020, 2016 | 739 | 2016 |
| PD-L1: CD80 cis-heterodimer triggers the co-stimulatory receptor CD28 while repressing the inhibitory PD-1 and CTLA-4 pathways Y Zhao, CK Lee, CH Lin, RB Gassen, X Xu, Z Huang, C Xiao, C Bonorino, ... Immunity 51 (6), 1059-1073. e9, 2019 | 300 | 2019 |
| Metformin induces human esophageal carcinoma cell pyroptosis by targeting the miR-497/PELP1 axis L Wang, K Li, X Lin, Z Yao, S Wang, X Xiong, Z Ning, J Wang, X Xu, ... Cancer letters 450, 22-31, 2019 | 190 | 2019 |
| Mechanistic convergence of the TIGIT and PD-1 inhibitory pathways necessitates co-blockade to optimize anti-tumor CD8+ T cell responses KL Banta, X Xu, AS Chitre, A Au-Yeung, C Takahashi, WE O’Gorman, ... Immunity 55 (3), 512-526. e9, 2022 | 185 | 2022 |
| Mechanistic insights revealed by the crystal structure of a histidine kinase with signal transducer and sensor domains C Wang, J Sang, J Wang, M Su, JS Downey, Q Wu, S Wang, Y Cai, X Xu, ... PLoS biology 11 (2), e1001493, 2013 | 184 | 2013 |
| Group-DIA: analyzing multiple data-independent acquisition mass spectrometry data files Y Li, CQ Zhong, X Xu, S Cai, X Wu, Y Zhang, J Chen, J Shi, S Lin, J Han Nature methods 12 (12), 1105-1106, 2015 | 113 | 2015 |
| RIP1-dependent linear and nonlinear recruitments of caspase-8 and RIP3 respectively to necrosome specify distinct cell death outcomes X Li, CQ Zhong, R Wu, X Xu, ZH Yang, S Cai, X Wu, X Chen, Z Yin, Q He, ... Protein & Cell 12 (11), 858-876, 2021 | 95 | 2021 |
| PD-1 and BTLA regulate T cell signaling differentially and only partially through SHP1 and SHP2 X Xu, B Hou, A Fulzele, T Masubuchi, Y Zhao, Z Wu, Y Hu, Y Jiang, Y Ma, ... Journal of Cell Biology 219 (6), e201905085, 2020 | 92 | 2020 |
| Investigation of receptor interacting protein (RIP3)-dependent protein phosphorylation by quantitative phosphoproteomics X Wu, L Tian, J Li, Y Zhang, V Han, Y Li, X Xu, H Li, X Chen, J Chen, ... Molecular & Cellular Proteomics 11 (12), 1640-1651, 2012 | 81 | 2012 |
| Gene deletion of Gabarap enhances Nlrp3 inflammasome-dependent inflammatory responses Z Zhang, X Xu, J Ma, J Wu, Y Wang, R Zhou, J Han The Journal of Immunology 190 (7), 3517-3524, 2013 | 41 | 2013 |
| Molecular features underlying differential SHP1/SHP2 binding of immune checkpoint receptors X Xu, T Masubuchi, Q Cai, Y Zhao, E Hui Elife 10, e74276, 2021 | 37 | 2021 |
| Quantitative phosphoproteomic analysis of RIP3‐dependent protein phosphorylation in the course of TNF‐induced necroptosis CQ Zhong, Y Li, D Yang, N Zhang, X Xu, Y Wu, J Chen, J Han Proteomics 14 (6), 713-724, 2014 | 29 | 2014 |
| cis-B7: CD28 interactions at invaginated synaptic membranes provide CD28 co-stimulation and promote CD8+ T cell function and anti-tumor immunity Y Zhao, C Caron, YY Chan, CK Lee, X Xu, J Zhang, T Masubuchi, C Wu, ... Immunity 56 (6), 1187-1203. e12, 2023 | 27 | 2023 |
| Chimeric RNA ASTN2-PAPPAas aggravates tumor progression and metastasis in human esophageal cancer L Wang, X Xiong, Z Yao, J Zhu, Y Lin, W Lin, K Li, X Xu, Y Guo, Y Chen, ... Cancer letters 501, 1-11, 2021 | 21 | 2021 |
| CTLA4 depletes T cell endogenous and trogocytosed B7 ligands via cis-endocytosis X Xu, P Dennett, J Zhang, A Sherrard, Y Zhao, T Masubuchi, JD Bui, ... Journal of Experimental Medicine 220 (7), e20221391, 2023 | 13 | 2023 |
| BTLA and PD-1 employ distinct phosphatases to differentially repress T cell signaling X Xu, A Fulzele, Y Zhao, Z Wu, Y Hu, Y Jiang, Y Ma, H Wang, G Fu, ... BioRxiv, 669812, 2019 | 7 | 2019 |
| Molecular Features Underlying Shp1/Shp2 Discrimination by Immune Checkpoint Receptors X Xu, T Masubuchi, Y Zhao, E Hui bioRxiv, 2021.06. 23.449580, 2021 | 1 | 2021 |
| Cis-B7:CD28 interactions at invaginated synaptic membranes activate CD28 and promote T cell function Y Zhao, C Caron, YY Chan, CK Lee, X Xu, JD Bui, E Hui Cancer Research 83 (7_Supplement), 606-606, 2023 | | 2023 |
| PD-L1: CD80 Heterodimer Triggers CD28 While Repressing Both PD-1 and CTLA4 Pathways Y Zhao, CH Lin, C Lee, X Xu, Z Huang, C Xiao, J Bui, LF Lu, E Hui bioRxiv, 615138, 2019 | | 2019 |
