Dissection of DNA double-strand-break repair using novel single-molecule forceps JL Wang, C Duboc, Q Wu, T Ochi, S Liang, SE Tsutakawa, SP Lees-Miller, ... Nature structural & molecular biology 25 (6), 482-487, 2018 | 89 | 2018 |
Dimers of DNA-PK create a stage for DNA double-strand break repair AK Chaplin, SW Hardwick, S Liang, A Kefala Stavridi, A Hnizda, ... Nature structural & molecular biology 28 (1), 13-19, 2021 | 82 | 2021 |
Cryo-EM of NHEJ supercomplexes provides insights into DNA repair AK Chaplin, SW Hardwick, AK Stavridi, CJ Buehl, NJ Goff, V Ropars, ... Molecular cell 81 (16), 3400-3409. e3, 2021 | 65 | 2021 |
Mechanism of efficient double-strand break repair by a long non-coding RNA R Thapar, JL Wang, M Hammel, R Ye, K Liang, C Sun, A Hnizda, S Liang, ... Nucleic acids research 48 (19), 10953-10972, 2020 | 57 | 2020 |
Structural insights into inhibitor regulation of the DNA repair protein DNA-PKcs S Liang, SE Thomas, AK Chaplin, SW Hardwick, DY Chirgadze, ... Nature 601 (7894), 643-648, 2022 | 54 | 2022 |
Understanding the structure and role of DNA-PK in NHEJ: how X-ray diffraction and cryo-EM contribute in complementary ways Q Wu, S Liang, T Ochi, DY Chirgadze, JT Huiskonen, TL Blundell Progress in Biophysics and Molecular Biology 147, 26-32, 2019 | 20 | 2019 |
Human DNA-dependent protein kinase activation mechanism S Liang, TL Blundell Nature Structural & Molecular Biology 30 (2), 140-147, 2023 | 14 | 2023 |
Achieving selectivity in space and time with DNA double-strand-break response and repair: molecular stages and scaffolds come with strings attached S Liang, SR Esswein, T Ochi, Q Wu, DB Ascher, D Chirgadze, BL Sibanda, ... Structural Chemistry 28, 161-171, 2017 | 12 | 2017 |
Stages, scaffolds and strings in the spatial organisation of non-homologous end joining: Insights from X-ray diffraction and Cryo-EM S Liang, AK Chaplin, AK Stavridi, R Appleby, A Hnizda, TL Blundell Progress in Biophysics and Molecular Biology 163, 60-73, 2021 | 9 | 2021 |
Druggable binding sites in the multicomponent assemblies that characterise DNA double-strand-break repair through non-homologous end joining A Kefala Stavridi, R Appleby, S Liang, TL Blundell, AK Chaplin Essays in Biochemistry 64 (5), 791-806, 2020 | 8 | 2020 |