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Charles Wykoff MD PhD
Charles Wykoff MD PhD
Retina Consultants of Texas, Director of Research; Retina Consultants of America; Blanton Eye
在 retinaconsultantstexas.com 的电子邮件经过验证 - 首页
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The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
PH Maxwell, MS Wiesener, GW Chang, SC Clifford, EC Vaux, ...
Nature 399 (6733), 271-275, 1999
62111999
Hypoxia-inducible expression of tumor-associated carbonic anhydrases
CC Wykoff, NJP Beasley, PH Watson, KJ Turner, J Pastorek, A Sibtain, ...
Cancer research 60 (24), 7075-7083, 2000
15972000
Diabetic retinopathy: a position statement by the American Diabetes Association
SD Solomon, E Chew, EJ Duh, L Sobrin, JK Sun, BL VanderBeek, ...
Diabetes care 40 (3), 412, 2017
9752017
HIF activation identifies early lesions in VHL kidneys: evidence for site-specific tumor suppressor function in the nephron
SJ Mandriota, KJ Turner, DR Davies, PG Murray, NV Morgan, HM Sowter, ...
Cancer cell 1 (5), 459-468, 2002
6222002
Prognostic significance of a novel hypoxia-regulated marker, carbonic anhydrase IX, in invasive breast carcinoma
SK Chia, CC Wykoff, PH Watson, C Han, RD Leek, J Pastorek, KC Gatter, ...
Journal of Clinical Oncology 19 (16), 3660-3668, 2001
5312001
Recombinant expression of caveolin-1 in oncogenically transformed cells abrogates anchorage-independent growth
JA Engelman, CC Wykoff, S Yasuhara, KS Song, T Okamoto, MP Lisanti
Journal of Biological Chemistry 272 (26), 16374-16381, 1997
4861997
Expression of hypoxia-inducible carbonic anhydrase-9 relates to angiogenic pathways and independently to poor outcome in non-small cell lung cancer
A Giatromanolaki, MI Koukourakis, E Sivridis, J Pastorek, CC Wykoff, ...
Cancer research 61 (21), 7992-7998, 2001
4432001
Complement C3 inhibitor pegcetacoplan for geographic atrophy secondary to age-related macular degeneration: a randomized phase 2 trial
DS Liao, FV Grossi, D El Mehdi, MR Gerber, DM Brown, JS Heier, ...
Ophthalmology 127 (2), 186-195, 2020
4352020
Carbonic anhydrase IX expression, a novel surrogate marker of tumor hypoxia, is associated with a poor prognosis in non–small-cell lung cancer
DEB Swinson, JL Jones, D Richardson, C Wykoff, H Turley, J Pastorek, ...
Journal of Clinical Oncology 21 (3), 473-482, 2003
3672003
Identification of novel hypoxia dependent and independent target genes of the von Hippel-Lindau (VHL) tumour suppressor by mRNA differential expression profiling
CC Wykoff, CW Pugh, PH Maxwell, AL Harris, PJ Ratcliffe
Oncogene 19 (54), 6297-6305, 2000
3452000
Carbonic anhydrase IX, an endogenous hypoxia marker, expression in head and neck squamous cell carcinoma and its relationship to hypoxia, necrosis, and microvessel density
NJP Beasley, CC Wykoff, PH Watson, R Leek, H Turley, K Gatter, ...
Cancer research 61 (13), 5262-5267, 2001
3302001
Efficacy, durability, and safety of intravitreal faricimab up to every 16 weeks for neovascular age-related macular degeneration (TENAYA and LUCERNE): two randomised, double …
JS Heier, AM Khanani, CQ Ruiz, K Basu, PJ Ferrone, C Brittain, ...
The Lancet 399 (10326), 729-740, 2022
3112022
Prospective trial of treat-and-extend versus monthly dosing for neovascular age-related macular degeneration: TREX-AMD 1-year results
CC Wykoff, DE Croft, DM Brown, R Wang, JF Payne, L Clark, ...
Ophthalmology 122 (12), 2514-2522, 2015
2972015
Expression of the hypoxia-inducible and tumor-associated carbonic anhydrases in ductal carcinoma in situ of the breast
CC Wykoff, N Beasley, PH Watson, L Campo, SK Chia, R English, ...
The American journal of pathology 158 (3), 1011-1019, 2001
2862001
Efficacy, durability, and safety of intravitreal faricimab with extended dosing up to every 16 weeks in patients with diabetic macular oedema (YOSEMITE and RHINE): two …
CC Wykoff, F Abreu, AP Adamis, K Basu, DA Eichenbaum, Z Haskova, ...
The Lancet 399 (10326), 741-755, 2022
2692022
Hypoxia-regulated carbonic anhydrase-9 (CA9) relates to poor vascularization and resistance of squamous cell head and neck cancer to chemoradiotherapy
MI Koukourakis, A Giatromanolaki, E Sivridis, K Simopoulos, J Pastorek, ...
Clinical Cancer Research 7 (11), 3399-3403, 2001
2592001
Simultaneous inhibition of angiopoietin-2 and vascular endothelial growth factor-A with faricimab in diabetic macular edema: BOULEVARD phase 2 randomized trial
J Sahni, SS Patel, PU Dugel, AM Khanani, CD Jhaveri, CC Wykoff, ...
Ophthalmology 126 (8), 1155-1170, 2019
2312019
Endogenous fungal endophthalmitis: causative organisms, management strategies, and visual acuity outcomes
A Lingappan, CC Wykoff, TA Albini, D Miller, A Pathengay, JL Davis, ...
American journal of ophthalmology 153 (1), 162-166. e1, 2012
2212012
Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (HIF) in regulating HIF transcriptional target genes
IP Stolze, YM Tian, RJ Appelhoff, H Turley, CC Wykoff, JM Gleadle, ...
Journal of Biological Chemistry 279 (41), 42719-42725, 2004
2102004
Exogenous fungal endophthalmitis: microbiology and clinical outcomes
CC Wykoff, HW Flynn Jr, D Miller, IU Scott, EC Alfonso
Ophthalmology 115 (9), 1501-1507. e2, 2008
2082008
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