Comprehensive molecular portraits of human breast tumours Brigham & Women’s Hospital & Harvard Medical School Chin Lynda 9 11 Park ... Nature 490 (7418), 61-70, 2012 | 11156 | 2012 |
Molecular heterogeneity and response to neoadjuvant human epidermal growth factor receptor 2 targeting in CALGB 40601, a randomized phase III trial of paclitaxel plus … LA Carey, DA Berry, CT Cirrincione, WT Barry, BN Pitcher, LN Harris, ... Journal of Clinical Oncology 34 (6), 542-549, 2016 | 401 | 2016 |
Genomic analysis of immune cell infiltrates across 11 tumor types MD Iglesia, JS Parker, KA Hoadley, JS Serody, CM Perou, BG Vincent Journal of the National Cancer Institute 108 (11), djw144, 2016 | 327 | 2016 |
Prognostic B-cell signatures using mRNA-seq in patients with subtype-specific breast and ovarian cancer MD Iglesia, BG Vincent, JS Parker, KA Hoadley, LA Carey, CM Perou, ... Clinical Cancer Research 20 (14), 3818-3829, 2014 | 287 | 2014 |
Claudin-low bladder tumors are immune infiltrated and actively immune suppressed J Kardos, S Chai, LE Mose, SR Selitsky, B Krishnan, R Saito, MD Iglesia, ... JCI insight 1 (3), 2016 | 215 | 2016 |
Treg depletion potentiates checkpoint inhibition in claudin-low breast cancer NA Taylor, SC Vick, MD Iglesia, WJ Brickey, BR Midkiff, KP McKinnon, ... The Journal of clinical investigation 127 (9), 3472-3483, 2017 | 149 | 2017 |
Tumor-specific retargeting of an oncogenic transcription factor chimera results in dysregulation of chromatin and transcription M Patel, JM Simon, MD Iglesia, SB Wu, AW McFadden, JD Lieb, IJ Davis Genome research 22 (2), 259-270, 2012 | 125 | 2012 |
Functional Annotation of ESR1 Gene Fusions in Estrogen Receptor-Positive Breast Cancer JT Lei, J Shao, J Zhang, M Iglesia, DW Chan, J Cao, M Anurag, P Singh, ... Cell reports 24 (6), 1434-1444. e7, 2018 | 102 | 2018 |
Spatially restricted drivers and transitional cell populations cooperate with the microenvironment in untreated and chemo-resistant pancreatic cancer D Cui Zhou, RG Jayasinghe, S Chen, JM Herndon, MD Iglesia, P Navale, ... Nature genetics 54 (9), 1390-1405, 2022 | 99 | 2022 |
Assembly-based inference of B-cell receptor repertoires from short read RNA sequencing data with V’DJer LE Mose, SR Selitsky, LM Bixby, DL Marron, MD Iglesia, JS Serody, ... Bioinformatics 32 (24), 3729-3734, 2016 | 70 | 2016 |
Epigenetic regulation during cancer transitions across 11 tumour types NV Terekhanova, A Karpova, WW Liang, A Strzalkowski, S Chen, Y Li, ... Nature 623 (7986), 432-441, 2023 | 19 | 2023 |
A phase II study of palbociclib plus letrozole plus trastuzumab as neoadjuvant treatment for clinical stages II and III ER+ HER2+ breast cancer (PALTAN) FO Ademuyiwa, DW Northfelt, T O’Connor, E Levine, J Luo, Y Tao, J Hoog, ... NPJ Breast Cancer 9 (1), 1, 2023 | 3 | 2023 |
Therapy Sequencing in Patients With Advanced Neuroendocrine Neoplasms RP Riechelmann, RG Taboada, VHF de Jesus, M Iglesia, NA Trikalinos American Society of Clinical Oncology Educational Book 43, e389278, 2023 | 2 | 2023 |
Abstract PD8-03: ESR1 gene fusions drive endocrine therapy resistance and metastasis in breast cancer JT Lei, J Shao, J Zhang, M Iglesia, DW Chan, J Cao, M Anurag, P Singh, ... Cancer Research 78 (4_Supplement), PD8-03-PD8-03, 2018 | 1 | 2018 |
The novel claudin-low molecular subtype of high-grade urothelial bladder cancer is highly immunogenic yet immunosuppressed BG Vincent, W Kim, J Kardos, S Chai, J Parker, L Mose, S Selitsky, ... Cancer Research 76 (14_Supplement), 5120-5120, 2016 | 1 | 2016 |
Allele-specific KRAS mutations as prognostic biomarkers in mucinous adenocarcinoma of the appendix and colorectal cancer. MM Khushman, HM Abushukair, S Alhushki, M Iglesia, KH Lim, X Liu, ... Journal of Clinical Oncology 42 (16_suppl), 3628-3628, 2024 | | 2024 |
Molecular insights into oxaliplatin-induced peripheral neuropathy in colorectal cancer: Unraveling a potential signature. S Modekurty, M Iglesia, KS Pedersen, C Salvador, S Haroutounian, ... Journal of Clinical Oncology 42 (16_suppl), e15506-e15506, 2024 | | 2024 |
Deciphering the roles of germline predisposition variants and somatic mutations on breast cancer cells and the tumor microenvironment FM Rodrigues, K Gallant, R Jayasinghe, M Iglesia, A Houston, S Chen, ... Cancer Research 84 (6_Supplement), 1773-1773, 2024 | | 2024 |
Morph: A feature extraction toolset for spatial transcriptomics ALNT da Costa, J Liu, CK Mo, E Storrs, AN Southard-Smith, ... Cancer Research 84 (6_Supplement), 2341-2341, 2024 | | 2024 |
Investigating the role of aging and treatment-induced senescence in the metastatic liver cancer tumor microenvironment K Gallant, A Karpova, X Li, M Iglesia, A Houston, D Rapp, CW Peng, C Liu, ... Cancer Research 84 (6_Supplement), 2961-2961, 2024 | | 2024 |