Awakening guardian angels: drugging the p53 pathway CJ Brown, S Lain, CS Verma, AR Fersht, DP Lane Nature Reviews Cancer 9 (12), 862-873, 2009 | 1095 | 2009 |
Drugging the p53 pathway: understanding the route to clinical efficacy KH Khoo, CS Verma, DP Lane Nature reviews Drug discovery 13 (3), 217-236, 2014 | 861 | 2014 |
Membrane active antimicrobial peptides: translating mechanistic insights to design J Li, JJ Koh, S Liu, R Lakshminarayanan, CS Verma, RW Beuerman Frontiers in neuroscience 11, 73, 2017 | 580 | 2017 |
Lapatinib, a HER2 tyrosine kinase inhibitor, induces stabilization and accumulation of HER2 and potentiates trastuzumab-dependent cell cytotoxicity M Scaltriti, C Verma, M Guzman, J Jimenez, JL Parra, K Pedersen, ... Oncogene 28 (6), 803-814, 2009 | 494 | 2009 |
Translating p53 into the clinic CF Cheok, CS Verma, J Baselga, DP Lane Nature reviews Clinical oncology 8 (1), 25-37, 2011 | 450 | 2011 |
The crystal structure of the L1 metallo-β-lactamase from Stenotrophomonas maltophilia at 1.7 Å resolution JH Ullah, TR Walsh, IA Taylor, DC Emery, CS Verma, SJ Gamblin, ... Journal of molecular biology 284 (1), 125-136, 1998 | 404 | 1998 |
Structural origins of the interfacial activation in Thermomyces (Humicola) lanuginosa lipase AM Brzozowski, H Savage, CS Verma, JP Turkenburg, DM Lawson, ... Biochemistry 39 (49), 15071-15082, 2000 | 299 | 2000 |
Stapled peptides with improved potency and specificity that activate p53 CJ Brown, ST Quah, J Jong, AM Goh, PC Chiam, KH Khoo, ML Choong, ... ACS chemical biology 8 (3), 506-512, 2013 | 250 | 2013 |
PDK1-SGK1 signaling sustains AKT-independent mTORC1 activation and confers resistance to PI3Kα inhibition P Castel, H Ellis, R Bago, E Toska, P Razavi, FJ Carmona, S Kannan, ... Cancer cell 30 (2), 229-242, 2016 | 227 | 2016 |
Functionalised staple linkages for modulating the cellular activity of stapled peptides YH Lau, P De Andrade, ST Quah, M Rossmann, L Laraia, N Sköld, ... Chemical science 5 (5), 1804-1809, 2014 | 207 | 2014 |
Rapid bactericidal action of alpha-mangostin against MRSA as an outcome of membrane targeting JJ Koh, S Qiu, H Zou, R Lakshminarayanan, J Li, X Zhou, C Tang, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1828 (2), 834-844, 2013 | 207 | 2013 |
The crystal structure of the globular domain of sheep prion protein LF Haire, SM Whyte, N Vasisht, AC Gill, C Verma, EJ Dodson, GG Dodson, ... Journal of molecular biology 336 (5), 1175-1183, 2004 | 204 | 2004 |
A comparison and optimization of methods and factors affecting the transformation of Escherichia coli WT Chan, CS Verma, DP Lane, SKE Gan Bioscience reports 33 (6), e00086, 2013 | 201 | 2013 |
Defensins knowledgebase: a manually curated database and information source focused on the defensins family of antimicrobial peptides S Seebah, A Suresh, S Zhuo, YH Choong, H Chua, D Chuon, ... Nucleic acids research 35 (suppl_1), D265-D268, 2007 | 185 | 2007 |
Mussel adhesion is dictated by time-regulated secretion and molecular conformation of mussel adhesive proteins L Petrone, A Kumar, CN Sutanto, NJ Patil, S Kannan, A Palaniappan, ... Nature communications 6 (1), 8737, 2015 | 181 | 2015 |
Prion and water: tight and dynamical hydration sites have a key role in structural stability A De Simone, GG Dodson, CS Verma, A Zagari, F Fraternali Proceedings of the National Academy of Sciences 102 (21), 7535-7540, 2005 | 179 | 2005 |
Multiple self-healing squamous epithelioma is caused by a disease-specific spectrum of mutations in TGFBR1 DR Goudie, M D'Alessandro, B Merriman, H Lee, I Szeverényi, S Avery, ... Nature genetics 43 (4), 365-369, 2011 | 177 | 2011 |
Molecular simulations of protein dynamics: new windows on mechanisms in biology GG Dodson, DP Lane, CS Verma EMBO reports 9 (2), 144-150, 2008 | 176 | 2008 |
The crystal structure of the AAA domain of the ATP-dependent protease FtsH of Escherichia coli at 1.5 Å resolution S Krzywda, AM Brzozowski, C Verma, K Karata, T Ogura, AJ Wilkinson Structure 10 (8), 1073-1083, 2002 | 161 | 2002 |
Understanding the mechanism of ice binding by type III antifreeze proteins AA Antson, DJ Smith, DI Roper, S Lewis, LSD Caves, CS Verma, ... Journal of molecular biology 305 (4), 875-889, 2001 | 159 | 2001 |