| Clinical findings with implications for genetic testing in families with clustering of colorectal cancer JT Wijnen, HFA Vasen, PM Khan, AH Zwinderman, H van der Klift, ... New England Journal of Medicine 339 (8), 511-518, 1998 | 496 | 1998 |
| Familial endometrial cancer in female carriers of MSH6 germline mutations J Wijnen, W Leeuw, H Vasen, H Klift, P Møller, A Stormorken, ... Nature genetics 23 (2), 142-144, 1999 | 494 | 1999 |
| MSH2 genomic deletions are a frequent cause of HNPCC J Wijnen, H van der Klift, H Vasen, PM Khan, F Menko, C Tops, ... Nature genetics 20 (4), 326-328, 1998 | 267 | 1998 |
| Molecular analysis of hereditary nonpolyposis colorectal cancer in the United States: high mutation detection rate among clinically selected families and characterization of an … A Wagner, A Barrows, JT Wijnen, H Van Der Klift, PF Franken, ... The American Journal of Human Genetics 72 (5), 1088-1100, 2003 | 250 | 2003 |
| Hereditary nonpolyposis colorectal cancer families not complying with the Amsterdam criteria show extremely low frequency of mismatch-repair-gene mutations J Wijnen, PM Khan, H Vasen, H van der Klift, A Mulder, ... The American Journal of Human Genetics 61 (2), 329-335, 1997 | 235 | 1997 |
| Lynch Syndrome Caused by Germline PMS2 Mutations: Delineating the Cancer Risk SW Ten Broeke, RM Brohet, CM Tops, HM van der Klift, ME Velthuizen, ... Journal of Clinical Oncology 33 (4), 319-325, 2015 | 227 | 2015 |
| Multiplicity in polyp count and extracolonic manifestations in 40 Dutch patients with MYH associated polyposis coli (MAP) M Nielsen, PF Franken, T Reinards, MM Weiss, A Wagner, H Van der Klift, ... Journal of medical genetics 42 (9), e54-e54, 2005 | 226 | 2005 |
| Cancer Risks for PMS2-Associated Lynch Syndrome SW Ten Broeke, HM van der Klift, CMJ Tops, S Aretz, I Bernstein, ... Journal of Clinical Oncology 36 (29), 2961-2968, 2018 | 193 | 2018 |
| Heterozygous mutations in PMS2 cause hereditary nonpolyposis colorectal carcinoma (Lynch syndrome) YMC Hendriks, S Jagmohan–Changur, HM van der Klift, H Morreau, ... Gastroenterology 130 (2), 312-322, 2006 | 185 | 2006 |
| Molecular analysis of the APC gene in 105 Dutch kindreds with familial adenomatous polyposis: 67 germline mutations identified by DGGE, PTT, and southern … RB van der Luijt, PM Khan, HFA Vasen, CMJ Tops, ... Human mutation 9 (1), 7-16, 1997 | 158 | 1997 |
| Majority of hMLH1 mutations responsible for hereditary nonpolyposis colorectal cancer cluster at the exonic region 15-16. J Wijnen, PM Khan, H Vasen, F Menko, H Van der Klift, M Van den Broek, ... American journal of human genetics 58 (2), 300, 1996 | 155 | 1996 |
| Seven new mutations in hMSH2, an HNPCC gene, identified by denaturing gradient-gel electrophoresis J Wijnen, H Vasen, PM Khan, FH Menko, H van der Klift, C van Leeuwen, ... American journal of human genetics 56 (5), 1060, 1995 | 152 | 1995 |
| Molecular characterization of the spectrum of genomic deletions in the mismatch repair genes MSH2, MLH1, MSH6, and PMS2 responsible for hereditary … H Van Der Klift, J Wijnen, A Wagner, P Verkuilen, C Tops, R Otway, ... Genes, Chromosomes and cancer 44 (2), 123-138, 2005 | 142 | 2005 |
| Eight novel inactivating germ line mutations at the APC gene identified by denaturing gradient gel electrophoresis R Fodde, R van der Luijt, J Wijnen, C Tops, H van der Klift, ... Genomics 13 (4), 1162-1168, 1992 | 130 | 1992 |
| Intronic variants in BRCA1 and BRCA2 that affect RNA splicing can be reliably selected by splice‐site prediction programs MPG Vreeswijk, JN Kraan, HM van der Klift, GR Vink, CJ Cornelisse, ... Human mutation 30 (1), 107-114, 2009 | 125 | 2009 |
| A founder mutation of the MSH2 gene and hereditary nonpolyposis colorectal cancer in the United States HT Lynch, SM Coronel, R Okimoto, H Hampel, K Sweet, JF Lynch, ... Jama 291 (6), 718-724, 2004 | 101 | 2004 |
| Prostate cancer is part of the hereditary non‐polyposis colorectal cancer (HNPCC) tumor spectrum C Soravia, H van der Klift, MA Bründler, JL Blouin, J Wijnen, P Hutter, ... American Journal of Medical Genetics Part A 121 (2), 159-162, 2003 | 86 | 2003 |
| Quantification of sequence exchange events between PMS2 and PMS2CL provides a basis for improved mutation scanning of lynch syndrome patients HM Van Der Klift, CMJ Tops, EC Bik, MW Boogaard, AM Borgstein, ... Human mutation 31 (5), 578-587, 2010 | 76 | 2010 |
| Splicing analysis for exonic and intronic mismatch repair gene variants associated with Lynch syndrome confirms high concordance between minigene assays and patient RNA analyses HM van der Klift, AML Jansen, N van der Steenstraten, EC Bik, CMJ Tops, ... Molecular genetics & genomic medicine 3 (4), 327-345, 2015 | 74 | 2015 |
| Paediatric intestinal cancer and polyposis due to bi-allelic PMS2 mutations: case series, review and follow-up guidelines JC Herkert, RC Niessen, MJW Olderode-Berends, HE Veenstra-Knol, ... European Journal of Cancer 47 (7), 965-982, 2011 | 72 | 2011 |
