Twist1-induced dissemination preserves epithelial identity and requires E-cadherin ER Shamir, E Pappalardo, DM Jorgens, K Coutinho, WT Tsai, K Aziz, ... Journal of Cell Biology 204 (5), 839-856, 2014 | 239 | 2014 |
Toxicity and adverse effects of Tamoxifen and other anti-estrogen drugs G Yang, S Nowsheen, K Aziz, AG Georgakilas Pharmacology & therapeutics 139 (3), 392-404, 2013 | 230 | 2013 |
Targeting DDX 3 with a small molecule inhibitor for lung cancer therapy GM Bol, F Vesuna, M Xie, J Zeng, K Aziz, N Gandhi, A Levine, A Irving, ... EMBO molecular medicine 7 (5), 648-669, 2015 | 206 | 2015 |
Complex DNA damage: a route to radiation-induced genomic instability and carcinogenesis IV Mavragani, Z Nikitaki, MP Souli, A Aziz, S Nowsheen, K Aziz, ... Cancers 9 (7), 91, 2017 | 178 | 2017 |
The AMPK–Parkin axis negatively regulates necroptosis and tumorigenesis by inhibiting the necrosome SB Lee, JJ Kim, SA Han, Y Fan, LS Guo, K Aziz, S Nowsheen, SS Kim, ... Nature cell biology 21 (8), 940-951, 2019 | 127 | 2019 |
Twist1 Suppresses Senescence Programs and Thereby Accelerates and Maintains Mutant Kras-Induced Lung Tumorigenesis PT Tran, EH Shroff, TF Burns, S Thiyagarajan, ST Das, T Zabuawala, ... PLoS genetics 8 (5), e1002650, 2012 | 124 | 2012 |
Targeting DNA damage and repair: embracing the pharmacological era for successful cancer therapy K Aziz, S Nowsheen, G Pantelias, G Iliakis, VG Gorgoulis, AG Georgakilas Pharmacology & therapeutics 133 (3), 334-350, 2012 | 116 | 2012 |
L3MBTL2 orchestrates ubiquitin signalling by dictating the sequential recruitment of RNF8 and RNF168 after DNA damage S Nowsheen, K Aziz, A Aziz, M Deng, B Qin, K Luo, KB Jeganathan, ... Nature cell biology 20 (4), 455-464, 2018 | 107 | 2018 |
Accumulation of oxidatively induced clustered DNA lesions in human tumor tissues S Nowsheen, RL Wukovich, K Aziz, PT Kalogerinis, CC Richardson, ... Mutation Research/Genetic Toxicology and Environmental Mutagenesis 674 (1-2 …, 2009 | 101 | 2009 |
The twist box domain is required for Twist1-induced prostate cancer metastasis RP Gajula, ST Chettiar, RD Williams, S Thiyagarajan, Y Kato, K Aziz, ... Molecular cancer research 11 (11), 1387-1400, 2013 | 90 | 2013 |
DNA-PKcs deficiency leads to persistence of oxidatively induced clustered DNA lesions in human tumor cells P Peddi, CW Loftin, JS Dickey, JM Hair, KJ Burns, K Aziz, DC Francisco, ... Free Radical Biology and Medicine 48 (10), 1435-1443, 2010 | 82 | 2010 |
Inhibition of TWIST1 Leads to Activation of Oncogene-Induced Senescence in Oncogene-Driven Non–Small Cell Lung Cancer TF Burns, I Dobromilskaya, SC Murphy, RP Gajula, S Thiyagarajan, ... Molecular Cancer Research 11 (4), 329-338, 2013 | 72 | 2013 |
Ccne1 overexpression causes chromosome instability in liver cells and liver tumor development in mice K Aziz, JF Limzerwala, I Sturmlechner, E Hurley, C Zhang, KB Jeganathan, ... Gastroenterology 157 (1), 210-226. e12, 2019 | 62 | 2019 |
The interplay between inflammation and oxidative stress in carcinogenesis S Nowsheen, K Aziz, T B Kryston, N F Ferguson, A Georgakilas Current molecular medicine 12 (6), 672-680, 2012 | 53 | 2012 |
Molecular markers for cancer prognosis and treatment: have we struck gold? S Nowsheen, K Aziz, MI Panayiotidis, AG Georgakilas Cancer letters 327 (1-2), 142-152, 2012 | 52 | 2012 |
Novel Hsp90 inhibitor NVP-AUY922 radiosensitizes prostate cancer cells N Gandhi, AT Wild, ST Chettiar, K Aziz, Y Kato, RP Gajula, RD Williams, ... Cancer biology & therapy 14 (4), 347-356, 2013 | 51 | 2013 |
Hedgehog pathway inhibition radiosensitizes non-small cell lung cancers J Zeng, K Aziz, ST Chettiar, BT Aftab, M Armour, R Gajula, N Gandhi, ... International Journal of Radiation Oncology* Biology* Physics 86 (1), 143-149, 2013 | 50 | 2013 |
Epigenetic inactivation of DNA repair in breast cancer S Nowsheen, K Aziz, PT Tran, VG Gorgoulis, ES Yang, AG Georgakilas Cancer letters 342 (2), 213-222, 2014 | 49 | 2014 |
Trastuzumab in female breast cancer patients with reduced left ventricular ejection fraction S Nowsheen, K Aziz, JY Park, A Lerman, HR Villarraga, KJ Ruddy, ... Journal of the American Heart Association 7 (15), e008637, 2018 | 48 | 2018 |
Concurrent versus sequential sorafenib therapy in combination with radiation for hepatocellular carcinoma AT Wild, N Gandhi, ST Chettiar, K Aziz, RP Gajula, RD Williams, R Kumar, ... PloS one 8 (6), e65726, 2013 | 42 | 2013 |