Reprogramming to recover youthful epigenetic information and restore vision Y Lu, B Brommer, X Tian, A Krishnan, M Meer, C Wang, DL Vera, Q Zeng, ... Nature 588 (7836), 124-129, 2020 | 550 | 2020 |
Soluble CD163 made by monocyte/macrophages is a novel marker of HIV activity in early and chronic infection prior to and after anti-retroviral therapy TH Burdo, MR Lentz, P Autissier, A Krishnan, E Halpern, S Letendre, ... Journal of Infectious Diseases 204 (1), 154-163, 2011 | 400 | 2011 |
Increased monocyte turnover from bone marrow correlates with severity of SIV encephalitis and CD163 levels in plasma TH Burdo, C Soulas, K Orzechowski, J Button, A Krishnan, C Sugimoto, ... PLoS pathogens 6 (4), e1000842, 2010 | 219 | 2010 |
Chronic morphine administration delays wound healing by inhibiting immune cell recruitment to the wound site JL Martin, L Koodie, AG Krishnan, R Charboneau, RA Barke, S Roy The American journal of pathology 176 (2), 786-799, 2010 | 147 | 2010 |
A small peptide antagonist of the Fas receptor inhibits neuroinflammation and prevents axon degeneration and retinal ganglion cell death in an inducible mouse model of glaucoma A Krishnan, AJ Kocab, DN Zacks, A Marshak-Rothstein, ... Journal of neuroinflammation 16, 1-15, 2019 | 102 | 2019 |
Morphine induced exacerbation of sepsis is mediated by tempering endotoxin tolerance through modulation of miR-146a S Banerjee, J Meng, S Das, A Krishnan, J Haworth, R Charboneau, ... Scientific reports 3 (1), 1977, 2013 | 73 | 2013 |
Overexpression of soluble Fas ligand following adeno-associated virus gene therapy prevents retinal ganglion cell death in chronic and acute murine models of glaucoma A Krishnan, F Fei, A Jones, P Busto, A Marshak-Rothstein, BR Ksander, ... The Journal of Immunology 197 (12), 4626-4638, 2016 | 53 | 2016 |
Morphine modulation of toll-like receptors in microglial cells potentiates neuropathogenesis in a HIV-1 model of coinfection with pneumococcal pneumoniae R Dutta, A Krishnan, J Meng, S Das, J Ma, S Banerjee, J Wang, ... Journal of Neuroscience 32 (29), 9917-9930, 2012 | 46 | 2012 |
Mouse model of ocular hypertension with retinal ganglion cell degeneration R Mukai, DH Park, Y Okunuki, E Hasegawa, G Klokman, CB Kim, ... PLoS One 14 (1), e0208713, 2019 | 27 | 2019 |
Reversal of ageing-and injury-induced vision loss by Tet-dependent epigenetic reprogramming Y Lu, A Krishnan, B Brommer, X Tian, M Meer, DL Vera, C Wang, Q Zeng, ... BioRxiv, 710210, 2019 | 26 | 2019 |
Morphine withdrawal inhibits IL-12 induction in a macrophage cell line through a mechanism that involves cAMP J Kelschenbach, J Ninkovic, J Wang, A Krishnan, R Charboneau, ... The Journal of Immunology 180 (6), 3670-3679, 2008 | 22 | 2008 |
Preventing glaucoma by blocking activation of the NLRP3 inflammasome in the optic nerve head F Fei, A Krishnan, AM Rothstein, BR Ksander, MS Gregory-Ksander Investigative Ophthalmology & Visual Science 56 (7), 3485-3485, 2015 | 8 | 2015 |
Sustained vision recovery by OSK gene therapy in a mouse model of glaucoma MM Karg, YR Lu, N Refaian, J Cameron, E Hoffmann, C Hoppe, ... Cellular Reprogramming 25 (6), 288-299, 2023 | 5 | 2023 |
PolySialic acid-nanoparticles inhibit macrophage mediated inflammation through Siglec agonism: A potential treatment for age related macular degeneration A Krishnan, VG Sendra, D Patel, A Lad, MK Greene, P Smyth, ... Frontiers in Immunology 14, 1237016, 2023 | 5 | 2023 |
Pharmacologic inhibition of the NLRP3 inflammasome-a novel neuroprotective therapy for glaucoma A Krishnan, M Dua, CH Mitchell, W Lu, MS Gregory-Ksander Investigative Ophthalmology & Visual Science 60 (9), 2256-2256, 2019 | 3 | 2019 |
Soluble Fas ligand provides long-term protection in a chronic mouse model of glaucoma by inhibiting glial activation, inflammation, and apoptosis MS Gregory-Ksander, F Fei, A Marshak-Rothstein, B Ksander, A Krishnan Investigative Ophthalmology & Visual Science 57 (12), 2016 | 3 | 2016 |
Sialic Acid Mimetic Microglial Sialic Acid-Binding Immunoglobulin-like Lectin Agonism: Potential to Restore Retinal Homeostasis and Regain Visual Function in Age-Related … MJ Tolentino, AJ Tolentino, EM Tolentino, A Krishnan, MA Genead Pharmaceuticals 16 (12), 1735, 2023 | 2 | 2023 |
Modulation of macrophages and complement dysfunction in nonexudative age-related macular degeneration utilizing a sialic-acid coated nanoparticle BD Kuppermann, D Callanan, T Hassan, M Tolentino, C Scott, M Genead, ... Investigative Ophthalmology & Visual Science 64 (8), 3239-3239, 2023 | 2 | 2023 |
Modulation of retinal inflammatory macrophages by sialic-acid coated nanoparticles as novel mechanism for nonexudative AMD treatment A Krishnan, D Patel, VG Sendra, A Lad, D Callanan, T Hassan, ... Investigative Ophthalmology & Visual Science 64 (8), 2730-2730, 2023 | 2 | 2023 |
Targeting self-recognition pattern receptors on retina immune cells with an engineered glycan-coated nanoparticle as a novel therapy for nonexudative AMD D Patel, A Lad, D Callanan, T Hassan, M Tolentino, C Scott, M Genead, ... Investigative Ophthalmology & Visual Science 64 (8), 2959-2959, 2023 | 2 | 2023 |