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Steven Watterson
Steven Watterson
Lecturer in Computational Biology, Ulster University
在 ulster.ac.uk 的电子邮件经过验证 - 首页
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The systems biology graphical notation
N Le Novere, M Hucka, H Mi, S Moodie, F Schreiber, A Sorokin, E Demir, ...
Nature biotechnology 27 (8), 735-741, 2009
10512009
The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response
M Blanc, WY Hsieh, KA Robertson, KA Kropp, T Forster, G Shui, P Lacaze, ...
Immunity 38 (1), 106-118, 2013
3982013
Host defense against viral infection involves interferon mediated down-regulation of sterol biosynthesis
M Blanc, WY Hsieh, KA Robertson, S Watterson, G Shui, P Lacaze, ...
PLoS-Biology 9 (3), 455, 2011
3022011
Propionibacterium acnes and Acne Vulgaris: New Insights from the Integration of Population Genetic, Multi-Omic, Biochemical and Host-Microbe Studies
J McLaughlin, S Watterson, AM Layton, AJ Bjourson, E Barnard, ...
Microorganisms 7 (5), 128, 2019
2182019
The genetics and screening of familial hypercholesterolaemia
R Henderson, M O’Kane, V McGilligan, S Watterson
Journal of Biomedical Science 23 (1), 39, 2016
1772016
Systems medicine disease maps: community-driven comprehensive representation of disease mechanisms
A Mazein, M Ostaszewski, I Kuperstein, S Watterson, N Le Novère, ...
NPJ systems biology and applications 4 (1), 21, 2018
932018
A comprehensive machine-readable view of the mammalian cholesterol biosynthesis pathway
A Mazein, S Watterson, WY Hsieh, WJ Griffiths, P Ghazal
Biochemical Pharmacology 86 (1), 56-66, 2013
932013
Digital clocks: simple Boolean models can quantitatively describe circadian systems
OE Akman, S Watterson, A Parton, N Binns, AJ Millar, P Ghazal
Journal of The Royal Society Interface 9 (74), 2365-2382, 2012
822012
Logic models of pathway biology
S Watterson, S Marshall, P Ghazal
Drug discovery today 13 (9-10), 447-456, 2008
812008
Computational modelling of atherosclerosis
A Parton, V McGilligan, M O’Kane, FR Baldrick, S Watterson
Briefings in Bioinformatics 17 (4), 562-575, 2016
682016
Construction of a large scale integrated map of macrophage pathogen recognition and effector systems
S Raza, N McDerment, PA Lacaze, K Robertson, S Watterson, Y Chen, ...
BMC systems biology 4, 1-18, 2010
512010
An Interferon Regulated MicroRNA Provides Broad Cell-Intrinsic Antiviral Immunity through Multihit Host-Directed Targeting of the Sterol Pathway
KA Robertson, WY Hsieh, T Forster, M Blanc, H Lu, PJ Crick, E Yutuc, ...
PLoS Biol 14 (3), e1002364, 2016
452016
The interdependency and co-regulation of the vitamin D and cholesterol metabolism
T Warren, R McAllister, A Morgan, TS Rai, V McGilligan, M Ennis, C Page, ...
Cells 10 (8), 2007, 2021
442021
Deep Learning in Systems Medicine
E Pujos-Guillot, B Comte, JL de Miranda, V Spiwok, I Chorbev, ...
Briefings in Bioinformatics 22 (2), 1543-1559, 2021
41*2021
A model of flux regulation in the cholesterol biosynthesis pathway: Immune mediated graduated flux reduction versus statin-like led stepped flux reduction
S Watterson, ML Guerriero, M Blanc, A Mazein, L Loewe, KA Robertson, ...
Biochimie 95 (3), 613-621, 2013
382013
Role of tumour necrosis factor alpha converting enzyme (TACE/ADAM17) and associated proteins in coronary artery disease and cardiac events
M Chemaly, V McGilligan, M Gibson, M Clauss, S Watterson, ...
Archives of cardiovascular diseases 110 (12), 700-711, 2017
362017
Rapid proteasomal elimination of 3-hydroxy-3-methylglutaryl-CoA reductase by interferon-γ in primary macrophages requires endogenous 25-hydroxycholesterol synthesis
H Lu, S Talbot, KA Robertson, S Watterson, T Forster, D Roy, P Ghazal
Steroids 99, 219-229, 2015
352015
Network and systems medicine: Position paper of the european collaboration on science and technology action on open multiscale systems medicine
B Comte, J Baumbach, A Benis, J Basílio, N Debeljak, Å Flobak, ...
Network and systems medicine 3 (1), 67-90, 2020
262020
New models of atherosclerosis and multi-drug therapeutic interventions.
A Parton, V McGilligan, M Chemaly, M O’Kane, S Watterson
Bioinformatics 35 (14), 2449-2457, 2018
252018
The need for standardizing diagnosis, treatment and clinical care of cholecystitis and biliary colic in gallbladder disease
G Doherty, M Manktelow, B Skelly, P Gillespie, AJ Bjourson, S Watterson
Medicina 58 (3), 388, 2022
192022
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