Autophagy initiation by ULK complex assembly on ER tubulovesicular regions marked by ATG9 vesicles E Karanasios, SA Walker, H Okkenhaug, M Manifava, E Hummel, ... Nature communications 7 (1), 12420, 2016 | 327 | 2016 |
Multi-omic rejuvenation of human cells by maturation phase transient reprogramming D Gill, A Parry, F Santos, H Okkenhaug, CD Todd, I Hernando-Herraez, ... Elife 11, e71624, 2022 | 139 | 2022 |
The H3K9 dimethyltransferases EHMT1/2 protect against pathological cardiac hypertrophy B Thienpont, JM Aronsen, EL Robinson, H Okkenhaug, E Loche, A Ferrini, ... The Journal of clinical investigation 127 (1), 335-348, 2017 | 131 | 2017 |
RDGBα, a PtdIns-PtdOH transfer protein, regulates G-protein-coupled PtdIns(4,5)P2 signalling during Drosophila phototransduction S Yadav, K Garner, P Georgiev, M Li, E Gomez-Espinosa, A Panda, ... Journal of cell science 128 (17), 3330-3344, 2015 | 96 | 2015 |
An mTORC1-to-CDK1 switch maintains autophagy suppression during mitosis RI Odle, SA Walker, D Oxley, AM Kidger, K Balmanno, R Gilley, ... Molecular cell 77 (2), 228-240. e7, 2020 | 91 | 2020 |
Mutual antagonism between IP3RII and miRNA-133a regulates calcium signals and cardiac hypertrophy FM Drawnel, D Wachten, JD Molkentin, M Maillet, JM Aronsen, F Swift, ... The Journal of Cell Biology 199 (5), 783-798, 2012 | 89 | 2012 |
Rhabdomere biogenesis in Drosophila photoreceptors is acutely sensitive to phosphatidic acid levels P Raghu, E Coessens, M Manifava, P Georgiev, T Pettitt, E Wood, ... Journal of Cell Biology 185 (1), 129-145, 2009 | 79 | 2009 |
lazaro encodes a lipid phosphate phosphohydrolase that regulates phosphatidylinositol turnover during Drosophila phototransduction I Garcia-Murillas, T Pettitt, E Macdonald, H Okkenhaug, P Georgiev, ... Neuron 49 (4), 533-546, 2006 | 76 | 2006 |
Follicular regulatory T cells can access the germinal center independently of CXCR5 I Vanderleyden, SC Fra-Bido, S Innocentin, M Stebegg, H Okkenhaug, ... Cell reports 30 (3), 611-619. e4, 2020 | 55 | 2020 |
A critical role of TET1/2 proteins in cell-cycle progression of trophoblast stem cells S Chrysanthou, CE Senner, L Woods, E Fineberg, H Okkenhaug, S Burge, ... Stem cell reports 10 (4), 1355-1368, 2018 | 53 | 2018 |
Calcium phosphate particles stimulate interleukin-1β release from human vascular smooth muscle cells: A role for spleen tyrosine kinase and exosome release Y Dautova, AN Kapustin, K Pappert, M Epple, H Okkenhaug, SJ Cook, ... Journal of molecular and cellular cardiology 115, 82-93, 2018 | 53 | 2018 |
TRPM channels mediate zinc homeostasis and cellular growth during Drosophila larval development P Georgiev, H Okkenhaug, A Drews, D Wright, S Lambert, M Flick, V Carta, ... Cell metabolism 12 (4), 386-397, 2010 | 49 | 2010 |
The human ClC‐4 protein, a member of the CLC chloride channel/transporter family, is localized to the endoplasmic reticulum by its N‐terminus H Okkenhaug, KH Weylandt, D Carmena, DJ Wells, CF Higgins, A Sardini, ... The FASEB journal 20 (13), 2390-2392, 2006 | 46 | 2006 |
Satellite repeat transcripts modulate heterochromatin condensates and safeguard chromosome stability in mouse embryonic stem cells CL Novo, EV Wong, C Hockings, C Poudel, E Sheekey, M Wiese, ... Nature communications 13 (1), 3525, 2022 | 45 | 2022 |
Context-dependent effects of IL-2 rewire immunity into distinct cellular circuits CE Whyte, K Singh, OT Burton, M Aloulou, L Kouser, RV Veiga, ... Journal of Experimental Medicine 219 (7), e20212391, 2022 | 45 | 2022 |
BAP1/ASXL complex modulation regulates epithelial-mesenchymal transition during trophoblast differentiation and invasion V Perez-Garcia, G Lea, P Lopez-Jimenez, H Okkenhaug, GJ Burton, ... Elife 10, e63254, 2021 | 44 | 2021 |
Mechanistic insights into regulation of the ALC1 remodeler by the nucleosome acidic patch LC Lehmann, L Bacic, G Hewitt, K Brackmann, A Sabantsev, G Gaullier, ... Cell reports 33 (12), 2020 | 28 | 2020 |
IKKα plays a major role in canonical NF-κB signalling in colorectal cells JA Prescott, K Balmanno, JP Mitchell, H Okkenhaug, SJ Cook Biochemical Journal 479 (3), 305-325, 2022 | 16 | 2022 |
Neuronal HSF-1 coordinates the propagation of fat desaturation across tissues to enable adaptation to high temperatures in C. elegans L Chauve, F Hodge, S Murdoch, F Masoudzadeh, HJ Mann, ... PLoS biology 19 (11), e3001431, 2021 | 16 | 2021 |
Smarcad1 mediates microbiota-induced inflammation in mouse and coordinates gene expression in the intestinal epithelium J Kazakevych, J Denizot, A Liebert, M Portovedo, M Mosavie, P Jain, ... Genome biology 21, 1-20, 2020 | 16 | 2020 |