Transcription factors and evolution: an integral part of gene expression T Mitsis, A Efthimiadou, F Bacopoulou, D Vlachakis, GP Chrousos, ... World Academy of Sciences Journal 2 (1), 3-8, 2020 | 142 | 2020 |
Current state-of-the-art molecular dynamics methods and applications D Vlachakis, E Bencurova, N Papangelopoulos, S Kossida Advances in protein chemistry and structural biology 94, 269-313, 2014 | 107 | 2014 |
EnzyNet: enzyme classification using 3D convolutional neural networks on spatial representation A Amidi, S Amidi, D Vlachakis, V Megalooikonomou, N Paragios, ... PeerJ 6, e4750, 2018 | 104 | 2018 |
STING orchestrates the crosstalk between polyunsaturated fatty acid metabolism and inflammatory responses IK Vila, H Chamma, A Steer, M Saccas, C Taffoni, E Turtoi, LS Reinert, ... Cell metabolism 34 (1), 125-139. e8, 2022 | 74 | 2022 |
Genomic big data hitting the storage bottleneck L Papageorgiou, P Eleni, S Raftopoulou, M Mantaiou, ... EMBnet. journal 24, 2018 | 71 | 2018 |
Statistical and machine learning techniques in human microbiome studies: contemporary challenges and solutions I Moreno-Indias, L Lahti, M Nedyalkova, I Elbere, G Roshchupkin, ... Frontiers in microbiology 12, 635781, 2021 | 63 | 2021 |
Discovery of a novel HCV helicase inhibitor by a de novo drug design approach S Kandil, S Biondaro, D Vlachakis, AC Cummins, A Coluccia, C Berry, ... Bioorganic & medicinal chemistry letters 19 (11), 2935-2937, 2009 | 62 | 2009 |
A novel point mutation of the human glucocorticoid receptor gene causes primary generalized glucocorticoid resistance through impaired interaction with the LXXLL motif of the … NC Nicolaides, ML Roberts, T Kino, G Braatvedt, DE Hurt, E Katsantoni, ... The Journal of Clinical Endocrinology & Metabolism 99 (5), E902-E907, 2014 | 60 | 2014 |
Competitive inhibition of human poly (A)-specific ribonuclease (PARN) by synthetic fluoro-pyranosyl nucleosides NAA Balatsos, D Vlachakis, P Maragozidis, S Manta, D Anastasakis, ... Biochemistry 48 (26), 6044-6051, 2009 | 60 | 2009 |
Evaluation of plant growth promoting bacteria strains on growth, yield and quality of industrial tomato N Katsenios, V Andreou, P Sparangis, N Djordjevic, M Giannoglou, ... Microorganisms 9 (10), 2099, 2021 | 52 | 2021 |
Gromita: a fully integrated graphical user interface to gromacs 4 D Sellis, D Vlachakis, M Vlassi Bioinformatics and biology insights 3, BBI. S3207, 2009 | 50 | 2009 |
State-of-the-art technology in modern computer-aided drug design GA Dalkas, D Vlachakis, D Tsagkrasoulis, A Kastania, S Kossida Briefings in bioinformatics 14 (6), 745-752, 2013 | 48 | 2013 |
An updated evolutionary study of Flaviviridae NS3 helicase and NS5 RNA-dependent RNA polymerase reveals novel invariable motifs as potential pharmacological targets L Papageorgiou, S Loukatou, K Sofia, D Maroulis, D Vlachakis Molecular BioSystems 12 (7), 2080-2093, 2016 | 45 | 2016 |
A holistic evolutionary and structural study of flaviviridae provides insights into the function and inhibition of HCV helicase D Vlachakis, VL Koumandou, S Kossida PeerJ 1, e74, 2013 | 41 | 2013 |
Phosphorylation of the arginine/serine repeats of lamin B receptor by SRPK1—Insights from molecular dynamics simulations D Sellis, V Drosou, D Vlachakis, N Voukkalis, T Giannakouros, M Vlassi Biochimica et Biophysica Acta (BBA)-General Subjects 1820 (1), 44-55, 2012 | 40 | 2012 |
Functional toll-like receptor 9 expression and CXCR3 ligand release in pulmonary sarcoidosis J Schnerch, A Prasse, D Vlachakis, KL Schuchardt, DV Pechkovsky, ... American journal of respiratory cell and molecular biology 55 (5), 749-757, 2016 | 37 | 2016 |
Molecular dynamics simulations through GPU video games technologies S Loukatou, L Papageorgiou, P Fakourelis, A Filntisi, E Polychronidou, ... Journal of molecular biochemistry 3 (2), 64, 2014 | 36 | 2014 |
Introducing Drugster: a comprehensive and fully integrated drug design, lead and structure optimization toolkit D Vlachakis, D Tsagrasoulis, V Megalooikonomou, S Kossida Bioinformatics 29 (1), 126-128, 2013 | 36 | 2013 |
Molecular mechanisms of the novel coronavirus SARS-CoV-2 and potential anti-COVID19 pharmacological targets since the outbreak of the pandemic D Vlachakis, E Papakonstantinou, T Mitsis, K Pierouli, I Diakou, ... Food and Chemical Toxicology 146, 111805, 2020 | 35 | 2020 |
Directed evolution of Tau class glutathione transferases reveals a site that regulates catalytic efficiency and masks co-operativity I Axarli, AW Muleta, D Vlachakis, S Kossida, G Kotzia, A Maltezos, ... Biochemical Journal 473 (5), 559-570, 2016 | 35 | 2016 |