Single HIV-1 imaging reveals progression of infection through CA-dependent steps of docking at the nuclear pore, uncoating, and nuclear transport AC Francis, GB Melikyan Cell host & microbe 23 (4), 536-548. e6, 2018 | 193 | 2018 |
Structural and mechanistic bases for a potent HIV-1 capsid inhibitor SM Bester, G Wei, H Zhao, D Adu-Ampratwum, N Iqbal, VV Courouble, ... Science 370 (6514), 360-364, 2020 | 142 | 2020 |
Time-Resolved Imaging of Single HIV-1 Uncoating In Vitro and in Living Cells AC Francis, M Marin, J Shi, C Aiken, GB Melikyan PLoS pathogens 12 (6), e1005709, 2016 | 141 | 2016 |
HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains AC Francis, M Marin, PK Singh, V Achuthan, MJ Prellberg, ... Nature communications 11 (1), 3505, 2020 | 132 | 2020 |
Siglec-1 initiates formation of the virus-containing compartment and enhances macrophage-to-T cell transmission of HIV-1 JE Hammonds, N Beeman, L Ding, S Takushi, AC Francis, JJ Wang, ... PLoS pathogens 13 (1), e1006181, 2017 | 91 | 2017 |
Proteome-wide characterization of the RNA-binding protein RALY-interactome using the in vivo-biotinylation-pulldown-quant (iBioPQ) approach S Tenzer, A Moro, J Kuharev, AC Francis, L Vidalino, A Provenzani, ... Journal of proteome research 12 (6), 2869-2884, 2013 | 60 | 2013 |
HIV-1 uncoating and nuclear import precede the completion of reverse transcription in cell lines and in primary macrophages AC Francis, M Marin, MJ Prellberg, K Palermino-Rowland, GB Melikyan Viruses 12 (11), 1234, 2020 | 55 | 2020 |
Sec24C is an HIV-1 host dependency factor crucial for virus replication SV Rebensburg, G Wei, RC Larue, J Lindenberger, AC Francis, ... Nature microbiology 6 (4), 435-444, 2021 | 51 | 2021 |
Exploring modifications of an HIV-1 capsid inhibitor: design, synthesis, and mechanism of action JP Xu, AC Francis, ME Meuser, M Mankowski, RG Ptak, AA Rashad, ... Journal of drug design and research 5 (2), 2018 | 48 | 2018 |
HIV-1 integrase tetramers are the antiviral target of pyridine-based allosteric integrase inhibitors PC Koneru, AC Francis, N Deng, SV Rebensburg, AC Hoyte, ... Elife 8, e46344, 2019 | 44 | 2019 |
Live-cell imaging of early steps of single HIV-1 infection AC Francis, GB Melikyan Viruses 10 (5), 275, 2018 | 42 | 2018 |
A novel phenotype links HIV-1 capsid stability to cGAS-mediated DNA sensing MA Siddiqui, A Saito, UD Halambage, D Ferhadian, DK Fischer, ... Journal of virology 93 (16), 10.1128/jvi. 00706-19, 2019 | 38 | 2019 |
Second generation imaging of nuclear/cytoplasmic HIV-1 complexes AC Francis, C Di Primio, V Quercioli, P Valentini, A Boll, G Girelli, ... AIDS research and human retroviruses 30 (7), 717-726, 2014 | 32 | 2014 |
An improved labeling strategy enables automated detection of single-virus fusion and assessment of HIV-1 protease activity in single virions C Sood, AC Francis, TM Desai, GB Melikyan Journal of Biological Chemistry 292 (49), 20196-20207, 2017 | 26 | 2017 |
Role of phosphorylation in the nuclear biology of HIV-1 A C Francis, C Di Primio, A Allouch, A Cereseto Current medicinal chemistry 18 (19), 2904-2912, 2011 | 22 | 2011 |
Prion-like low complexity regions enable avid virus-host interactions during HIV-1 infection G Wei, N Iqbal, VV Courouble, AC Francis, PK Singh, A Hudait, ... Nature Communications 13 (1), 5879, 2022 | 20 | 2022 |
Prevalence and pattern of cross-reacting antibodies to HIV in patients with tuberculosis S Swaminathan, LE Hanna, JC Sundaramurthi, A Leonard, ... AIDS research and human retroviruses 24 (7), 941-946, 2008 | 18 | 2008 |
Localization and functions of native and eGFP-tagged capsid proteins in HIV-1 particles AC Francis, A Cereseto, PK Singh, J Shi, E Poeschla, AN Engelman, ... PLoS Pathogens 18 (8), e1010754, 2022 | 13 | 2022 |
HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains. Nat Commun 11: 3505 AC Francis, M Marin, PK Singh, V Achuthan, MJ Prellberg, ... | 11 | 2020 |
Sec24C is an HIV-1 host dependency factor crucial for virus replication. Nat Microbiol 6: 435–444 SV Rebensburg, G Wei, RC Larue, J Lindenberger, AC Francis, ... | 8 | 2021 |