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Anna Scotto Rosato
Anna Scotto Rosato
intellectual property specialist, Thermo Fisher
在 thermofisher.com 的电子邮件经过验证 - 首页
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Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB
DL Medina, S Di Paola, I Peluso, A Armani, D De Stefani, R Venditti, ...
Nature cell biology 17 (3), 288-299, 2015
12402015
Agonist-mediated switching of ion selectivity in TPC2 differentially promotes lysosomal function
S Gerndt, CC Chen, YK Chao, Y Yuan, S Burgstaller, A Scotto Rosato, ...
Elife 9, e54712, 2020
1462020
TRPML1: The Ca (2+) retaker of the lysosome
S Di Paola, A Scotto-Rosato, DL Medina
Cell calcium 69, 112-121, 2018
1432018
TRPML1 links lysosomal calcium to autophagosome biogenesis through the activation of the CaMKKβ/VPS34 pathway
A Scotto Rosato, S Montefusco, C Soldati, S Di Paola, A Capuozzo, ...
Nature communications 10 (1), 5630, 2019
1362019
Selective agonist of TRPML2 reveals direct role in chemokine release from innate immune cells
E Plesch, CC Chen, E Butz, A Scotto Rosato, EK Krogsaeter, H Yinan, ...
Elife 7, e39720, 2018
912018
Lung emphysema and impaired macrophage elastase clearance in mucolipin 3 deficient mice
B Spix, ES Butz, CC Chen, AS Rosato, R Tang, A Jeridi, V Kudrina, ...
Nature communications 13 (1), 318, 2022
442022
Flavonoids increase melanin production and reduce proliferation, migration and invasion of melanoma cells by blocking endolysosomal/melanosomal TPC2
P Netcharoensirisuk, C Abrahamian, R Tang, CC Chen, AS Rosato, ...
Scientific Reports 11 (1), 8515, 2021
432021
Repurposing of tamoxifen ameliorates CLN3 and CLN7 disease phenotype
C Soldati, I Lopez‐Fabuel, LG Wanderlingh, M Garcia‐Macia, ...
EMBO molecular medicine 13 (10), e13742, 2021
352021
Two-pore and TRPML cation channels: regulators of phagocytosis, autophagy and lysosomal exocytosis
AS Rosato, R Tang, C Grimm
Pharmacology & Therapeutics 220, 107713, 2021
332021
Estradiol analogs attenuate autophagy, cell migration and invasion by direct and selective inhibition of TRPML1, independent of estrogen receptors
P Rühl, AS Rosato, N Urban, S Gerndt, R Tang, C Abrahamian, C Leser, ...
Scientific reports 11 (1), 8313, 2021
312021
Fingolimod phosphate inhibits astrocyte inflammatory activity in mucolipidosis IV
LD Weinstock, AM Furness, SS Herron, SS Smith, SB Sankar, SG DeRosa, ...
Human molecular genetics 27 (15), 2725-2738, 2018
282018
TPC2 rescues lysosomal storage in mucolipidosis type IV, Niemann–Pick type C1, and Batten disease
A Scotto Rosato, EK Krogsaeter, D Jaślan, C Abrahamian, S Montefusco, ...
EMBO molecular medicine 14 (9), e15377, 2022
272022
Segregated cation flux by TPC2 biases Ca2+ signaling through lysosomes
Y Yuan, D Jaślan, T Rahman, SR Bolsover, V Arige, LE Wagner, ...
Nature communications 13 (1), 4481, 2022
192022
TRPMLs and TPCs: Targets for lysosomal storage and neurodegenerative disease therapy?
E Krogsaeter, AS Rosato, C Grimm
Cell Calcium 103, 102553, 2022
162022
Neurodegenerative lysosomal storage disorders: TPC2 comes to the rescue!
S Prat Castro, V Kudrina, D Jaślan, J Böck, A Scotto Rosato, C Grimm
Cells 11 (18), 2807, 2022
92022
579 Prezioso C, Forrester A, Settembre C, Wang W, Gao Q, Xu H, Sandri M, Rizzuto R, De Matteis MA, and 580 Ballabio A
DL Medina, S Di Paola, I Peluso, A Armani, D De Stefani, R Venditti, ...
Lysosomal calcium signalling regulates autophagy through calcineurin and …, 2015
32015
TRPML1 activation ameliorates lysosomal phenotypes in CLN3 deficient retinal pigment epithelial cells
D Wünkhaus, R Tang, K Nyame, NN Laqtom, M Schweizer, AS Rosato, ...
bioRxiv, 2023.06. 21.545896, 2023
12023
TRPML1: Role in Autophagy and Potential Target to Treat Lysosomal Storage Disorders
AS Rosato
PQDT-Global, 2018
12018
The role of endolysosomal ion channels in cancer
C Abrahamian, P Netcharoensirisuk, P Ruehl, AS Rosato, R Tang, ...
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 394 (SUPPL 1), S33-S33, 2021
2021
Aginist-dependent switching of ion selectivity in a lsosomal ion channel
YK Chao, S Gerndt, CC Chen, Y Yuan, AS Rosato, E Krogsaeter, N Urban, ...
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 393 (SUPPL 1), 8-8, 2020
2020
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