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Ian Backstrom
Ian Backstrom
The Hospital for Sick Children
在 sickkids.ca 的电子邮件经过验证
标题
引用次数
引用次数
年份
Genome-wide detection of tandem DNA repeats that are expanded in autism
B Trost, W Engchuan, CM Nguyen, B Thiruvahindrapuram, E Dolzhenko, ...
Nature 586 (7827), 80-86, 2020
1872020
Nanoscale reaction vessels designed for synthesis of copper-drug complexes suitable for preclinical development
M Wehbe, M Anantha, I Backstrom, A Leung, K Chen, A Malhotra, ...
PloS one 11 (4), e0153416, 2016
552016
Sulfonation, an underexploited area: from skeletal development to infectious diseases and cancer
AWY Leung, I Backstrom, MB Bally
Oncotarget 7 (34), 55811, 2016
502016
Impact of Commercial Strain Use on Saccharomyces cerevisiae Population Structure and Dynamics in Pinot Noir Vineyards and Spontaneous Fermentations of a …
JT Martiniuk, B Pacheco, G Russell, S Tong, I Backstrom, V Measday
PLoS One 11 (8), e0160259, 2016
482016
Genome-wide tandem repeat expansions contribute to schizophrenia risk
BA Mojarad, W Engchuan, B Trost, I Backstrom, Y Yin, ...
Molecular Psychiatry 27 (9), 3692-3698, 2022
302022
Genome sequencing broadens the range of contributing variants with clinical implications in schizophrenia
BA Mojarad, Y Yin, R Manshaei, I Backstrom, G Costain, T Heung, ...
Translational Psychiatry 11 (1), 84, 2021
212021
Determination of an optimal dosing schedule for combining Irinophore C™ and temozolomide in an orthotopic model of glioblastoma
M Verreault, M Wehbe, D Strutt, D Masin, M Anantha, D Walker, F Chu, ...
Journal of Controlled Release 220, 348-357, 2015
202015
Combined use of gene expression modeling and siRNA screening identifies genes and pathways which enhance the activity of cisplatin when added at no effect levels to non-small …
AWY Leung, SS Hung, I Backstrom, D Ricaurte, B Kwok, S Poon, ...
PloS one 11 (3), e0150675, 2016
172016
In Vivo Validation of PAPSS1 (3′-phosphoadenosine 5′-phosphosulfate synthase 1) as a Cisplatin-sensitizing Therapeutic Target
AWY Leung, CJ Veinotte, N Melong, MH Oh, K Chen, KSS Enfield, ...
Clinical Cancer Research 23 (21), 6555-6566, 2017
142017
Rare tandem repeat expansions associate with genes involved in synaptic and neuronal signaling functions in schizophrenia
J Wen, B Trost, W Engchuan, M Halvorsen, LM Pallotto, A Mitina, ...
Molecular Psychiatry 28 (1), 475-482, 2023
132023
Genome sequencing identifies rare tandem repeat expansions and copy number variants in Lennox–Gastaut syndrome
F Qaiser, T Sadoway, Y Yin, Q Zulfiqar Ali, CM Nguyen, N Shum, ...
Brain communications 3 (3), fcab207, 2021
132021
Genome-wide enhancer-associated tandem repeats are expanded in cardiomyopathy
A Mitina, M Khan, R Lesurf, Y Yin, W Engchuan, O Hamdan, G Pellecchia, ...
EBioMedicine 101, 2024
32024
PAPSS1 (3’-phosphoadenosine 5’-phosphosulfate synthase 1) inhibition sensitizes non-small cell lung cancer to cisplatin treatment in vivo
AWY Leung, CJ Veinotte, N Melong, I Backstrom, C Warburton, ...
Cancer Research 76 (14_Supplement), 3792-3792, 2016
22016
Repurposing disulfiram for use as an anticancer drug: a story about metabolism and metal binding
M Wehbe, M Anantha, I Backstrom, A Leung, K Chen, M Shi, A Malhotra, ...
Cancer Research 76 (14_Supplement), 3914-3914, 2016
12016
Development and characterization of an injectable copper clioquinol formulation: repurposing of a topical antifungal for treatment of cancer
M Wehbe, M Anantha, I Backstrom, A Malhotra, K Edwards, M Bally
Cancer Research 76 (14_Supplement), 2206-2206, 2016
12016
Family-Based Genome Analysis Identifies Clinically Relevant de novo Variants in Pediatric Dystonia (4446)
B Adhamimojarad, Y Yin, I Backstrom, R Yuen, T Soman
Neurology 94 (15_supplement), 4446, 2020
2020
P. 053 Whole-genome sequencing identified a frameshift mutation at LMNB1 in a family with early-onset dystonia
RK Yuen, B Adhami-Mojarad, I Backstrom, A Yin, T Soman
Canadian Journal of Neurological Sciences 46 (s1), S28-S28, 2019
2019
Plasmid-Lipid Nanoparticles: A potent tool for manipulating neuronal genes in vitro and in vivo
R Desouza, A Thomas, I Backstrom, E Ouellet, S Garg, J Singh, S Chang, ...
2017 Controlled Release Society Annual Meeting, 2017
2017
Welcome to My Research! layer
M Wehbe, M Anantha, I Backstrom, A Leung, K Chen
Lipid-Based Nanoparticulate Formulation of Copper-Diethyldithiocarbamate: The Active Agent When Using Disulfiram for Treating Cancer
M Wehbe, M Anantha, I Backstrom, A Malhotra, MB Bally
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