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Frederick Gimble
Frederick Gimble
Associate Professor, Department of Biochemistry, Purdue University
在 purdue.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Protein splicing elements: inteins and exteins--a definition of terms and recommended nomenclature.
FB Perler, EO Davis, GE Dean, FS Gimble, WE Jack, N Neff, CJ Noren, ...
Nucleic acids research 22 (7), 1125, 1994
5681994
Homing of a DNA endonuclease gene by meiotic gene conversion in Saccharomyces cerevisiae
FS Gimble, J Thorner
Nature 357 (6376), 301-306, 1992
3591992
Crystal structure of PI-SceI, a homing endonuclease with protein splicing activity
X Duan, FS Gimble, FA Quiocho
Cell 89 (4), 555-564, 1997
3581997
Invasion of a multitude of genetic niches by mobile endonuclease genes
FS Gimble
FEMS Microbiology Letters 185 (2), 99-107, 2000
1872000
Crystal structure of the intein homing endonuclease PI-SceI bound to its recognition sequence
CM Moure, FS Gimble, FA Quiocho
Nature structural biology 9 (10), 764-770, 2002
1462002
Substitutions in Conserved Dodecapeptide Motifs That Uncouple the DNA Binding and DNA Cleavage Activities of PI-SceI Endonuclease (∗)
FS Gimble, BW Stephens
Journal of Biological Chemistry 270 (11), 5849-5856, 1995
1321995
The crystal structure of the gene targeting homing endonuclease I-SceI reveals the origins of its target site specificity
CM Moure, FS Gimble, FA Quiocho
Journal of molecular biology 334 (4), 685-695, 2003
1312003
Substrate recognition and induced DNA distortion by the PI-SceI endonuclease, an enzyme generated by protein splicing
FS Gimble, J Wang
Journal of molecular biology 263 (2), 163-180, 1996
1311996
Stimulation of intrachromosomal homologous recombination in human cells by electroporation with site-specific endonucleases.
M Brenneman, FS Gimble, JH Wilson
Proceedings of the National Academy of Sciences 93 (8), 3608-3612, 1996
981996
Assessing the plasticity of DNA target site recognition of the PI-SceI homing endonuclease using a bacterial two-hybrid selection system
FS Gimble, CM Moure, KL Posey
Journal of molecular biology 334 (5), 993-1008, 2003
932003
Purification and characterization of VDE, a site-specific endonuclease from the yeast Saccharomyces cerevisiae.
FS Gimble, J Thorner
Journal of Biological Chemistry 268 (29), 21844-21853, 1993
831993
Engineering variants of the I-SceI homing endonuclease with strand-specific and site-specific DNA-nicking activity
Y Niu, K Tenney, H Li, FS Gimble
Journal of molecular biology 382 (1), 188-202, 2008
782008
λ Repressor mutants that are better substrates for RecA-mediated cleavage
FS Gimble, RT Sauer
Journal of molecular biology 206 (1), 29-39, 1989
771989
Amino acid residues in both the protein splicing and endonuclease domains of the PI-SceI intein mediate DNA binding
Z He, M Crist, H Yen, X Duan, FA Quiocho, FS Gimble
Journal of Biological Chemistry 273 (8), 4607-4615, 1998
761998
λ repressor inactivation: properties of purified Ind− proteins in the autodigestion and RecA-mediated cleavage reactions
FS Gimble, RT Sauer
Journal of molecular biology 192 (1), 39-47, 1986
651986
Mutations in bacteriophage lambda repressor that prevent RecA-mediated cleavage
FS Gimble, RT Sauer
Journal of bacteriology 162 (1), 147-154, 1985
601985
VDE endonuclease cleaves Saccharomyces cerevisiae genomic DNA at a single site: physical mapping of the VMA1 gene.
MC Bremer, FS Gimble, J Thorner, CL Smith
Nucleic acids research 20 (20), 5484, 1992
531992
Probing the structure of the PI-SceI-DNA complex by affinity cleavage and affinity photocross-linking
D Hu, M Crist, X Duan, FA Quiocho, FS Gimble
Journal of Biological Chemistry 275 (4), 2705-2712, 2000
512000
Putting protein splicing to work
FS Gimble
Chemistry & biology 5 (10), R251-R256, 1998
441998
Evolution of divergent DNA recognition specificities in VDE homing endonucleases from two yeast species
KL Posey, V Koufopanou, A Burt, FS Gimble
Nucleic acids research 32 (13), 3947-3956, 2004
412004
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