| Smoothened (SMO) receptor mutations dictate resistance to vismodegib in basal cell carcinoma S Pricl, B Cortelazzi, V Dal Col, D Marson, E Laurini, M Fermeglia, ... Molecular oncology 9 (2), 389-397, 2015 | 200 | 2015 |
| A dual targeting dendrimer-mediated siRNA delivery system for effective gene silencing in cancer therapy Y Dong, T Yu, L Ding, E Laurini, Y Huang, M Zhang, Y Weng, S Lin, ... Journal of the American Chemical Society 140 (47), 16264-16274, 2018 | 183 | 2018 |
| Antifungal and antimycobacterial activity of 1-(3, 5-diaryl-4, 5-dihydro-1H-pyrazol-4-yl)-1H-imidazole derivatives D Zampieri, MG Mamolo, E Laurini, G Scialino, E Banfi, L Vio Bioorganic & medicinal chemistry 16 (8), 4516-4522, 2008 | 135 | 2008 |
| Interfacial tension of oil/water emulsions with mixed non-ionic surfactants: comparison between experiments and molecular simulations P Posocco, A Perazzo, V Preziosi, E Laurini, S Pricl, S Guido RSC advances 6 (6), 4723-4729, 2016 | 133 | 2016 |
| Efficient delivery of sticky siRNA and potent gene silencing in a prostate cancer model using a generation 5 triethanolamine-core PAMAM dendrimer X Liu, C Liu, E Laurini, P Posocco, S Pricl, F Qu, P Rocchi, L Peng Molecular Pharmaceutics 9 (3), 470-481, 2012 | 131 | 2012 |
| Homology Model and Docking-Based Virtual Screening for Ligands of the σ1 Receptor E Laurini, VD Col, MG Mamolo, D Zampieri, P Posocco, M Fermeglia, ... ACS medicinal chemistry letters 2 (11), 834-839, 2011 | 100 | 2011 |
| Mastering dendrimer self‐assembly for efficient siRNA delivery: from conceptual design to in vivo efficient gene silencing C Chen, P Posocco, X Liu, Q Cheng, E Laurini, J Zhou, C Liu, Y Wang, ... Small 12 (27), 3667-3676, 2016 | 96 | 2016 |
| Hitting the right spot: Mechanism of action of OPB-31121, a novel and potent inhibitor of the Signal Transducer and Activator of Transcription 3 (STAT3) L Brambilla, D Genini, E Laurini, J Merulla, L Perez, M Fermeglia, ... Molecular oncology 9 (6), 1194-1206, 2015 | 96 | 2015 |
| Synthesis, biological evaluation, and three-dimensional in silico pharmacophore model for σ1 receptor ligands based on a series of substituted benzo [d] oxazol-2 (3 H)-one … D Zampieri, MG Mamolo, E Laurini, C Florio, C Zanette, M Fermeglia, ... Journal of medicinal chemistry 52 (17), 5380-5393, 2009 | 93 | 2009 |
| Mitochondrial dysfunction induced by a SH2 domain-targeting STAT3 inhibitor leads to metabolic synthetic lethality in cancer cells D Genini, L Brambilla, E Laurini, J Merulla, G Civenni, S Pandit, ... Proceedings of the National Academy of Sciences 114 (25), E4924-E4933, 2017 | 90 | 2017 |
| Role of Rad51 and DNA repair in cancer: A molecular perspective E Laurini, D Marson, A Fermeglia, S Aulic, M Fermeglia, S Pricl Pharmacology & therapeutics 208, 107492, 2020 | 89 | 2020 |
| Molecular dynamics reveal BCR-ABL1 polymutants as a unique mechanism of resistance to PAN-BCR-ABL1 kinase inhibitor therapy DL Gibbons, S Pricl, P Posocco, E Laurini, M Fermeglia, H Sun, M Talpaz, ... Proceedings of the National Academy of Sciences 111 (9), 3550-3555, 2014 | 89 | 2014 |
| Poly (amidoamine)‐based dendrimer/siRNA complexation studied by computer simulations: effects of pH and generation on dendrimer structure and siRNA Binding K Karatasos, P Posocco, E Laurini, S Pricl Macromolecular Bioscience 12 (2), 225-240, 2012 | 89 | 2012 |
| Multiscale Molecular Modeling of Clay–Polymer Nanocomposites E Laurini, P Posocco, M Fermeglia, S Pricl Clay-Polymer Nanocomposites, 83-112, 2017 | 88 | 2017 |
| Dendrimeric nanosystem consistently circumvents heterogeneous drug response and resistance in pancreatic cancer J Liu, C Chen, T Wei, O Gayet, C Loncle, L Borge, N Dusetti, X Ma, ... Exploration 1 (1), 21-34, 2021 | 81 | 2021 |
| Self-assembling supramolecular dendrimer nanosystem for PET imaging of tumors P Garrigue, J Tang, L Ding, A Bouhlel, A Tintaru, E Laurini, Y Huang, ... Proceedings of the National Academy of Sciences 115 (45), 11454-11459, 2018 | 80 | 2018 |
| Computational alanine scanning and structural analysis of the SARS-CoV-2 spike protein/angiotensin-converting enzyme 2 complex E Laurini, D Marson, S Aulic, M Fermeglia, S Pricl ACS nano 14 (9), 11821-11830, 2020 | 72 | 2020 |
| The Sigma Enigma: In Vitro/in Silico Site-Directed Mutagenesis Studies Unveil σ1 Receptor Ligand Binding S Brune, D Schepmann, KH Klempnauer, D Marson, V Dal Col, E Laurini, ... Biochemistry 53 (18), 2993-3003, 2014 | 62 | 2014 |
| Pd-Catalyzed Direct C–H Bond Functionalization of Spirocyclic σ1 Ligands: Generation of a Pharmacophore Model and Analysis of the Reverse Binding Mode by Docking into … C Meyer, D Schepmann, S Yanagisawa, J Yamaguchi, V Dal Col, ... Journal of medicinal chemistry 55 (18), 8047-8065, 2012 | 60 | 2012 |
| 3-Aryl-2-[1H-benzotriazol-1-yl] acrylonitriles: A novel class of potent tubulin inhibitors A Carta, I Briguglio, S Piras, G Boatto, P La Colla, R Loddo, M Tolomeo, ... European journal of medicinal chemistry 46 (9), 4151-4167, 2011 | 59 | 2011 |
Maurizio FermegliaUniversity of Trieste在 units.it 的电子邮件经过验证
