A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants LG Fritsche, W Igl, JNC Bailey, F Grassmann, S Sengupta, ... Nature genetics 48 (2), 134-143, 2016 | 1552 | 2016 |
Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma G Thorleifsson, GB Walters, AW Hewitt, G Masson, A Helgason, A DeWan, ... Nature genetics 42 (10), 906-909, 2010 | 469 | 2010 |
Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus Y Lu, V Vitart, KP Burdon, CC Khor, Y Bykhovskaya, A Mirshahi, ... Nature genetics 45 (2), 155-163, 2013 | 360 | 2013 |
Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries P Gharahkhani, E Jorgenson, P Hysi, AP Khawaja, S Pendergrass, X Han, ... Nature communications 12 (1), 1258, 2021 | 272 | 2021 |
Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression JE Craig, X Han, A Qassim, M Hassall, JN Cooke Bailey, TG Kinzy, ... Nature genetics 52 (2), 160-166, 2020 | 262 | 2020 |
Common genetic variants associated with open-angle glaucoma WD Ramdas, LME van Koolwijk, HG Lemij, F Pasutto, AJ Cree, ... Human molecular genetics 20 (12), 2464-2471, 2011 | 204 | 2011 |
Association between the SERPING1 gene and age-related macular degeneration: a two-stage case–control study S Ennis, C Jomary, R Mullins, A Cree, X Chen, A MacLeod, S Jones, ... The Lancet 372 (9652), 1828-1834, 2008 | 194 | 2008 |
Eplerenone for chronic central serous chorioretinopathy in patients with active, previously untreated disease for more than 4 months (VICI): a randomised, double-blind, placebo … A Lotery, S Sivaprasad, A O'Connell, RA Harris, L Culliford, L Ellis, A Cree, ... The Lancet 395 (10220), 294-303, 2020 | 192 | 2020 |
New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics H Springelkamp, AI Iglesias, A Mishra, R Höhn, R Wojciechowski, ... Human molecular genetics 26 (2), 438-453, 2017 | 191 | 2017 |
Increased high-density lipoprotein levels associated with age-related macular degeneration: evidence from the EYE-RISK and European Eye Epidemiology Consortia JM Colijn, AI den Hollander, A Demirkan, A Cougnard-Grégoire, ... Ophthalmology 126 (3), 393-406, 2019 | 122 | 2019 |
Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process H Springelkamp, R Höhn, A Mishra, PG Hysi, CC Khor, SJ Loomis, ... Nature communications 5 (1), 4883, 2014 | 120 | 2014 |
Complement factor H genetic variant and age-related macular degeneration: effect size, modifiers and relationship to disease subtype R Sofat, JP Casas, AR Webster, AC Bird, SS Mann, JRW Yates, AT Moore, ... International journal of epidemiology 41 (1), 250-262, 2012 | 112 | 2012 |
Genome-wide association study of age-related macular degeneration identifies associated variants in the TNXB–FKBPL–NOTCH4 region of chromosome 6p21.3 V Cipriani, HT Leung, V Plagnol, C Bunce, JC Khan, H Shahid, AT Moore, ... Human molecular genetics 21 (18), 4138-4150, 2012 | 106 | 2012 |
Interleukin-8 promoter polymorphism− 251A/T is a risk factor for age-related macular degeneration SV Goverdhan, S Ennis, SR Hannan, KC Madhusudhana, AJ Cree, ... British journal of ophthalmology 92 (4), 537-540, 2008 | 104 | 2008 |
Broad Institute Sequencing Platform and Whole Genome Assembly Team. Baylor College of Medicine Human Genome Sequencing Center Sequencing Team. Genome Institute at Washington … K Lindblad-Toh, M Garber, O Zuk, MF Lin, BJ Parker, S Washietl, ... Nature 478 (7370), 476-482, 2011 | 83 | 2011 |
Systemic and ocular determinants of peripapillary retinal nerve fiber layer thickness measurements in the European eye epidemiology (E3) population MM Mauschitz, PWM Bonnemaijer, K Diers, FG Rauscher, T Elze, C Engel, ... Ophthalmology 125 (10), 1526-1536, 2018 | 76 | 2018 |
Support for the involvement of complement factor I in age-related macular degeneration S Ennis, J Gibson, AJ Cree, A Collins, AJ Lotery European Journal of Human Genetics 18 (1), 15-16, 2010 | 73 | 2010 |
Genome-wide association study of primary open angle glaucoma risk and quantitative traits J Gibson, H Griffiths, G De Salvo, M Cole, A Jacob, A MacLeod, Y Yang, ... Molecular vision 18, 1083, 2012 | 71 | 2012 |
Pharmacogenetic associations with vascular endothelial growth factor inhibition in participants with neovascular age-related macular degeneration in the IVAN Study AJ Lotery, J Gibson, AJ Cree, SM Downes, SP Harding, CA Rogers, ... Ophthalmology 120 (12), 2637-2643, 2013 | 69 | 2013 |
Sorsby fundus dystrophy–a review of pathology and disease mechanisms DRG Christensen, FE Brown, AJ Cree, JA Ratnayaka, AJ Lotery Experimental eye research 165, 35-46, 2017 | 68 | 2017 |