A discrete genetic locus confers xyloglucan metabolism in select human gut Bacteroidetes J Larsbrink, TE Rogers, GR Hemsworth, LS McKee, AS Tauzin, O Spadiut, ... Nature 506 (7489), 498-502, 2014 | 515 | 2014 |
Discovery and characterization of a new family of lytic polysaccharide monooxygenases GR Hemsworth, B Henrissat, GJ Davies, PH Walton Nature chemical biology 10 (2), 122-126, 2014 | 437 | 2014 |
The molecular basis of polysaccharide cleavage by lytic polysaccharide monooxygenases KEH Frandsen, TJ Simmons, P Dupree, JCN Poulsen, GR Hemsworth, ... Nature chemical biology 12 (4), 298-303, 2016 | 353 | 2016 |
Structure and boosting activity of a starch-degrading lytic polysaccharide monooxygenase L Lo Leggio, TJ Simmons, JCN Poulsen, KEH Frandsen, GR Hemsworth, ... Nature communications 6 (1), 5961, 2015 | 337 | 2015 |
Lytic polysaccharide monooxygenases in biomass conversion GR Hemsworth, EM Johnston, GJ Davies, PH Walton Trends in biotechnology 33 (12), 747-761, 2015 | 329 | 2015 |
An ancient family of lytic polysaccharide monooxygenases with roles in arthropod development and biomass digestion F Sabbadin, GR Hemsworth, L Ciano, B Henrissat, P Dupree, T Tryfona, ... Nature communications 9 (1), 756, 2018 | 274 | 2018 |
Recent insights into copper-containing lytic polysaccharide mono-oxygenases GR Hemsworth, GJ Davies, PH Walton Current opinion in structural biology 23 (5), 660-668, 2013 | 249 | 2013 |
Spectroscopic and computational insight into the activation of O2 by the mononuclear Cu center in polysaccharide monooxygenases CH Kjaergaard, MF Qayyum, SD Wong, F Xu, GR Hemsworth, DJ Walton, ... Proceedings of the National Academy of Sciences 111 (24), 8797-8802, 2014 | 248 | 2014 |
The copper active site of CBM33 polysaccharide oxygenases GR Hemsworth, EJ Taylor, RQ Kim, RC Gregory, SJ Lewis, JP Turkenburg, ... Journal of the American Chemical Society 135 (16), 6069-6077, 2013 | 226 | 2013 |
Molecular mechanism by which prominent human gut bacteroidetes utilize mixed-linkage beta-glucans, major health-promoting cereal polysaccharides K Tamura, GR Hemsworth, G Déjean, TE Rogers, NA Pudlo, K Urs, N Jain, ... Cell reports 21 (2), 417-430, 2017 | 151 | 2017 |
Structural and functional insight into human O-GlcNAcase C Roth, S Chan, WA Offen, GR Hemsworth, LI Willems, DT King, ... Nature chemical biology 13 (6), 610-612, 2017 | 112 | 2017 |
Learning from microbial strategies for polysaccharide degradation GR Hemsworth, G Dejean, GJ Davies, H Brumer Biochemical Society Transactions 44 (1), 94-108, 2016 | 95 | 2016 |
Structure of the human obesity receptor leptin-binding domain reveals the mechanism of leptin antagonism by a monoclonal antibody B Carpenter, GR Hemsworth, Z Wu, M Maamra, CJ Strasburger, RJ Ross, ... Structure 20 (3), 487-497, 2012 | 89 | 2012 |
Heterogeneity in the histidine-brace copper coordination sphere in auxiliary activity family 10 (AA10) lytic polysaccharide monooxygenases AK Chaplin, MT Wilson, MA Hough, DA Svistunenko, GR Hemsworth, ... Journal of Biological Chemistry 291 (24), 12838-12850, 2016 | 72 | 2016 |
Activity, stability and 3-D structure of the Cu (II) form of a chitin-active lytic polysaccharide monooxygenase from Bacillus amyloliquefaciens RC Gregory, GR Hemsworth, JP Turkenburg, SJ Hart, PH Walton, ... Dalton Transactions 45 (42), 16904-16912, 2016 | 61 | 2016 |
Structural dissection of a complex Bacteroides ovatus gene locus conferring xyloglucan metabolism in the human gut GR Hemsworth, AJ Thompson, J Stepper, ŁF Sobala, T Coyle, J Larsbrink, ... Open Biology 6 (7), 160142, 2016 | 59 | 2016 |
Structural enzymology of Cellvibrio japonicus Agd31B protein reveals α-transglucosylase activity in glycoside hydrolase family 31 J Larsbrink, A Izumi, GR Hemsworth, GJ Davies, H Brumer Journal of Biological Chemistry 287 (52), 43288-43299, 2012 | 56 | 2012 |
The crystal structure of the Leishmania major deoxyuridine triphosphate nucleotidohydrolase in complex with nucleotide analogues, dUMP, and deoxyuridine GR Hemsworth, OV Moroz, MJ Fogg, B Scott, C Bosch-Navarrete, ... Journal of Biological Chemistry 286 (18), 16470-16481, 2011 | 44 | 2011 |
Discovery, activity and characterisation of an AA10 lytic polysaccharide oxygenase from the shipworm symbiont Teredinibacter turnerae CA Fowler, F Sabbadin, L Ciano, GR Hemsworth, L Elias, N Bruce, ... Biotechnology for biofuels 12, 1-11, 2019 | 39 | 2019 |
Insights into an unusual Auxiliary Activity 9 family member lacking the histidine brace motif of lytic polysaccharide monooxygenases KEH Frandsen, M Tovborg, CI Jørgensen, N Spodsberg, MN Rosso, ... Journal of Biological Chemistry 294 (45), 17117-17130, 2019 | 34 | 2019 |