In vitro antiherpes effects of a C‐glycosylflavonoid‐enriched fraction of Cecropia glaziovii Sneth* IT Silva, GM Costa, PH Stoco, EP Schenkel, FH Reginatto, CMO Simões Letters in applied microbiology 51 (2), 143-148, 2010 | 69 | 2010 |
Synthesis and cytotoxic activity evaluation of dihydrocucurbitacin B and cucurbitacin B derivatives KL Lang, IT Silva, LA Zimmermann, VR Machado, MR Teixeira, MI Lapuh, ... Bioorganic & medicinal chemistry 20 (9), 3016-3030, 2012 | 62 | 2012 |
Bioactive compounds from mangrove endophytic fungus and their uses for microorganism control RD Cadamuro, IMA da Silveira Bastos, IT Silva, ACC da Cruz, D Robl, ... Journal of fungi 7 (6), 455, 2021 | 55 | 2021 |
Strychnos pseudoquina A. St. Hil.: a Brazilian medicinal plant with promising in vitro antiherpes activity L Boff, IT Silva, DF Argenta, LM Farias, LF Alvarenga, RM Pádua, ... Journal of Applied Microbiology 121 (6), 1519-1529, 2016 | 45 | 2016 |
In Vitro and In Vivo Antitumor Activity of a Novel Semisynthetic Derivative of Cucurbitacin B IT Silva, A Carvalho, KL Lang, SE Dudek, D Masemann, FJ Durán, ... vivo, 2015 | 40 | 2015 |
Synergistic antiproliferative effects of a new cucurbitacin B derivative and chemotherapy drugs on lung cancer cell line A549 LL Marostica, IT Silva, JM Kratz, L Persich, FC Geller, KL Lang, MSB Caro, ... Chemical Research in Toxicology 28 (10), 1949-1960, 2015 | 36 | 2015 |
Antiherpes evaluation of soybean isoflavonoids DF Argenta, IT Silva, VL Bassani, LS Koester, HF Teixeira, CMO Simoes Archives of virology 160, 2335-2342, 2015 | 36 | 2015 |
Synthesis and cytotoxicity evaluation of glycosidic derivatives of lawsone against breast cancer cell lines FM Ottoni, ER Gomes, RM Pádua, MC Oliveira, IT Silva, RJ Alves Bioorganic & Medicinal Chemistry Letters 30 (2), 126817, 2020 | 32 | 2020 |
Cytotoxic effects of natural and semisynthetic cucurbitacins on lung cancer cell line A549 IT Silva, FC Geller, L Persich, SE Dudek, KL Lang, MSB Caro, FJ Durán, ... Investigational New Drugs 34, 139-148, 2016 | 32 | 2016 |
Effect of dexamethasone as osteogenic supplementation in in vitro osteogenic differentiation of stem cells from human exfoliated deciduous teeth MB Sordi, RB Curtarelli, IT da Silva, G Fongaro, CAM Benfatti, ... Journal of Materials Science: Materials in Medicine 32, 1-9, 2021 | 30 | 2021 |
Cytotoxic and cytostatic effects of digitoxigenin monodigitoxoside (DGX) in human lung cancer cells and its link to Na, K-ATPase NFZ Schneider, L Persich, SC Rocha, ACP Ramos, VF Cortes, IT Silva, ... Biomedicine & Pharmacotherapy 97, 684-696, 2018 | 29 | 2018 |
Isolation of three new ent-labdane diterpenes from Dodonaea viscosa Jacquin (Sapindaceae): Preliminary evaluation of antiherpes activity SQ de Oliveira, MTR de Almeida, F Maraslis, IT Silva, TCM Sincero, ... Phytochemistry Letters 5 (3), 500-505, 2012 | 26 | 2012 |
Cilistepoxide and cilistadiol, two new withanolides from Solanum sisymbiifolium R Niero, IT Da Silva, GC Tonial, BD Santos Camacho, E Gacs-Baitz, ... Natural Product Research 20 (13), 1164-1168, 2006 | 23 | 2006 |
A new semisynthetic cardenolide analog 3β-[2-(1-amantadine)-1-on-ethylamine]-digitoxigenin (AMANTADIG) affects G2/M cell cycle arrest and miRNA expression profiles and enhances … E Nolte, S Wach, IT Silva, S Lukat, AB Ekici, J Munkert, F Müller-Uri, ... Oncotarget 8 (7), 11676, 2017 | 21 | 2017 |
Multivariate SAR and QSAR of cucurbitacin derivatives as cytotoxic compounds in a human lung adenocarcinoma cell line KL Lang, IT Silva, VR Machado, LA Zimmermann, MSB Caro, ... Journal of Molecular Graphics and Modelling 48, 70-79, 2014 | 21 | 2014 |
Cytotoxicity of AMANTADIG–a semisynthetic digitoxigenin derivative–alone and in combination with docetaxel in human hormone-refractory prostate cancer cells and its effect on … IT Silva, J Munkert, E Nolte, NFZ Schneider, SC Rocha, ACP Ramos, ... Biomedicine & Pharmacotherapy 107, 464-474, 2018 | 17 | 2018 |
Long-circulating and fusogenic liposomes loaded with a glucoevatromonoside derivative induce potent antitumor response ER Gomes, MVM Novais, IT Silva, ALB Barros, EA Leite, J Munkert, ... Biomedicine & Pharmacotherapy 108, 1152-1161, 2018 | 15 | 2018 |
Cytotoxic effects of the cardenolide convallatoxin and its Na, K-ATPase regulation NFZ Schneider, IT Silva, L Persich, A de Carvalho, SC Rocha, L Marostica, ... Molecular and cellular biochemistry 428, 23-39, 2017 | 15 | 2017 |
New cytotoxic cucurbitacins from Wilbrandia ebracteata Cogn. KL Lang, T da Rosa Guimarães, VR Machado, LA Zimmermann, IT Silva, ... Planta medica 77 (14), 1648-1651, 2011 | 15 | 2011 |
Production of the cytotoxic cardenolide glucoevatromonoside by semisynthesis and biotransformation of evatromonoside by a Digitalis lanata cell culture J Munkert, MS Franco, E Nolte, IT Silva, RO Castilho, FM Ottoni, ... Planta Medica 83 (12/13), 1035-1043, 2017 | 14 | 2017 |