Mutation in TET2 in Myeloid Cancers F Delhommeau, S Dupont, VD Valle, C James, S Trannoy, A Massé, ... New England Journal of Medicine 360 (22), 2289-2301, 2009 | 2187 | 2009 |
TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis C Quivoron, L Couronné, V Della Valle, CK Lopez, I Plo, O Wagner-Ballon, ... Cancer cell 20 (1), 25-38, 2011 | 1018 | 2011 |
Role of Mre11 in chromosomal nonhomologous end joining in mammalian cells E Rass, A Grabarz, I Plo, J Gautier, P Bertrand, BS Lopez Nature structural & molecular biology 16 (8), 819-824, 2009 | 379 | 2009 |
Thrombopoietin receptor activation by myeloproliferative neoplasm associated calreticulin mutants I Chachoua, C Pecquet, M El-Khoury, H Nivarthi, RI Albu, C Marty, ... Blood, The Journal of the American Society of Hematology 127 (10), 1325-1335, 2016 | 367 | 2016 |
Calreticulin mutants in mice induce an MPL-dependent thrombocytosis with frequent progression to myelofibrosis C Marty, C Pecquet, H Nivarthi, M El-Khoury, I Chachoua, M Tulliez, ... Blood, The Journal of the American Society of Hematology 127 (10), 1317-1324, 2016 | 293 | 2016 |
Association of XRCC1 and tyrosyl DNA phosphodiesterase (Tdp1) for the repair of topoisomerase I-mediated DNA lesions I Plo, ZY Liao, JM Barceló, G Kohlhagen, KW Caldecott, M Weinfeld, ... DNA repair 2 (10), 1087-1100, 2003 | 244 | 2003 |
Inhibition of TET2-mediated conversion of 5-methylcytosine to 5-hydroxymethylcytosine disturbs erythroid and granulomonocytic differentiation of human hematopoietic progenitors E Pronier, C Almire, H Mokrani, A Vasanthakumar, A Simon, ... Blood, The Journal of the American Society of Hematology 118 (9), 2551-2555, 2011 | 216 | 2011 |
Defects in XRCC4 and KU80 differentially affect the joining of distal nonhomologous ends J Guirouilh-Barbat, E Rass, I Plo, P Bertrand, BS Lopez Proceedings of the National Academy of Sciences 104 (52), 20902-20907, 2007 | 216 | 2007 |
Presence of atypical thrombopoietin receptor (MPL) mutations in triple-negative essential thrombocythemia patients X Cabagnols, F Favale, F Pasquier, K Messaoudi, JP Defour, JC Ianotto, ... Blood, The Journal of the American Society of Hematology 127 (3), 333-342, 2016 | 206 | 2016 |
JAK2 stimulates homologous recombination and genetic instability: potential implication in the heterogeneity of myeloproliferative disorders I Plo, M Nakatake, L Malivert, JP de Villartay, S Giraudier, JL Villeval, ... Blood, The Journal of the American Society of Hematology 112 (4), 1402-1412, 2008 | 199 | 2008 |
A role for reactive oxygen species in JAK2V617F myeloproliferative neoplasm progression C Marty, C Lacout, N Droin, JP Le Couédic, V Ribrag, E Solary, ... Leukemia 27 (11), 2187-2195, 2013 | 189 | 2013 |
Tuning cytokine receptor signaling by re-orienting dimer geometry with surrogate ligands I Moraga, G Wernig, S Wilmes, V Gryshkova, CP Richter, WJ Hong, ... Cell 160 (6), 1196-1208, 2015 | 165 | 2015 |
JAK inhibitors for the treatment of myeloproliferative neoplasms and other disorders W Vainchenker, E Leroy, L Gilles, C Marty, I Plo, SN Constantinescu F1000Research 7, 2018 | 158 | 2018 |
Germline duplication of ATG2B and GSKIP predisposes to familial myeloid malignancies J Saliba, C Saint-Martin, A Di Stefano, G Lenglet, C Marty, B Keren, ... Nature genetics 47 (10), 1131-1140, 2015 | 151 | 2015 |
Differential association of calreticulin type 1 and type 2 mutations with myelofibrosis and essential thrombocytemia: relevance for disease evolution X Cabagnols, JP Defour, V Ugo, JC Ianotto, P Mossuz, J Mondet, ... Leukemia 29 (1), 249-252, 2015 | 149 | 2015 |
AKT1 inhibits homologous recombination by inducing cytoplasmic retention of BRCA1 and RAD51 I Plo, C Laulier, L Gauthier, F Lebrun, F Calvo, BS Lopez Cancer research 68 (22), 9404-9412, 2008 | 147 | 2008 |
JAK2V617F negatively regulates p53 stabilization by enhancing MDM2 via La expression in myeloproliferative neoplasms M Nakatake, B Monte-Mor, N Debili, N Casadevall, V Ribrag, E Solary, ... Oncogene 31 (10), 1323-1333, 2012 | 137 | 2012 |
Analysis of the Ten-Eleven Translocation 2 (TET2) gene in familial myeloproliferative neoplasms C Saint-Martin, G Leroy, F Delhommeau, G Panelatti, S Dupont, C James, ... Blood, The Journal of the American Society of Hematology 114 (8), 1628-1632, 2009 | 135 | 2009 |
Level of RUNX1 activity is critical for leukemic predisposition but not for thrombocytopenia I Antony-Debré, VT Manchev, N Balayn, D Bluteau, C Tomowiak, ... Blood, The Journal of the American Society of Hematology 125 (6), 930-940, 2015 | 120 | 2015 |
Mutations in the SRP54 gene cause severe congenital neutropenia as well as Shwachman-Diamond–like syndrome C Bellanné-Chantelot, B Schmaltz-Panneau, C Marty, O Fenneteau, ... Blood, The Journal of the American Society of Hematology 132 (12), 1318-1331, 2018 | 106 | 2018 |