Naturally occurring mitochondrial-derived peptides are age-dependent regulators of apoptosis, insulin sensitivity, and inflammatory markers LJ Cobb, C Lee, J Xiao, K Yen, RG Wong, HK Nakamura, HH Mehta, ... Aging (Albany NY) 8 (4), 796, 2016 | 237 | 2016 |
Mitochondrially derived peptides as novel regulators of metabolism SJ Kim, J Xiao, J Wan, P Cohen, K Yen The Journal of Physiology, doi:10.1113/JP274472, 2017 | 170 | 2017 |
The mitochondrial-derived peptide humanin activates the ERK1/2, AKT, and STAT3 signaling pathways and has age-dependent signaling differences in the hippocampus SJ Kim, N Guerrero, G Wassef, J Xiao, HH Mehta, P Cohen, K Yen Oncotarget 7 (30), 46899, 2016 | 95 | 2016 |
Effects of air pollution on mitochondrial function, mitochondrial DNA methylation, and mitochondrial peptide expression CV Breton, AY Song, J Xiao, SJ Kim, HH Mehta, J Wan, K Yen, C Sioutas, ... Mitochondrion 46, 22-29, 2019 | 90 | 2019 |
Humanin prevents age-related cognitive decline in mice and is associated with improved cognitive age in humans K Yen, J Wan, HH Mehta, B Miller, A Christensen, ME Levine, ... Scientific reports 8 (1), 14212, 2018 | 86 | 2018 |
Nuclear-encoded lncRNA MALAT1 epigenetically controls metabolic reprogramming in HCC cells through the mitophagy pathway Y Zhao, L Zhou, H Li, T Sun, X Wen, X Li, Y Meng, Y Li, M Liu, S Liu, ... Molecular Therapy-Nucleic Acids 23, 264-276, 2021 | 73 | 2021 |
The mitochondrial-derived peptides, HumaninS14G and small Humanin-like peptide 2, exhibit chaperone-like activity AK Okada, K Teranishi, F Lobo, JM Isas, J Xiao, K Yen, P Cohen, ... Scientific reports 7 (1), 7802, 2017 | 55 | 2017 |
The mitochondrial‐derived peptide MOTS‐c is a regulator of plasma metabolites and enhances insulin sensitivity SJ Kim, B Miller, HH Mehta, J Xiao, J Wan, TE Arpawong, K Yen, P Cohen Physiological reports 7 (13), e14171, 2019 | 52 | 2019 |
Humanin: functional interfaces with IGF-I J Xiao, SJ Kim, P Cohen, K Yen Growth hormone & IGF research 29, 21-27, 2016 | 49 | 2016 |
Mitochondrial DNA hypomethylation is a biomarker associated with induced senescence in human fetal heart mesenchymal stem cells D Yu, Z Du, L Pian, T Li, X Wen, W Li, SJ Kim, J Xiao, P Cohen, J Cui, ... Stem cells international 2017 (1), 1764549, 2017 | 48 | 2017 |
A pro-diabetogenic mtDNA polymorphism in the mitochondrial-derived peptide, MOTS-c H Zempo, SJ Kim, N Fuku, Y Nishida, Y Higaki, J Wan, K Yen, B Miller, ... Aging (Albany NY) 13 (2), 1692, 2021 | 41 | 2021 |
Metabolomic profile of diet-induced obesity mice in response to humanin and small humanin-like peptide 2 treatment HH Mehta, J Xiao, R Ramirez, B Miller, SJ Kim, P Cohen, K Yen Metabolomics 15, 1-12, 2019 | 41 | 2019 |
The potent humanin analogue (HNG) protects germ cells and leucocytes while enhancing chemotherapy-induced suppression of cancer metastases in male mice YH Lue, R Swerdloff, J Wan, J Xiao, S French, V Atienza, V Canela, ... Endocrinology 156 (12), 4511-4521, 2015 | 39 | 2015 |
Low circulating levels of the mitochondrial-peptide hormone SHLP2: novel biomarker for prostate cancer risk J Xiao, L Howard, J Wan, E Wiggins, A Vidal, P Cohen, SJ Freedland Oncotarget 8 (55), 94900, 2017 | 38 | 2017 |
Mitochondrial biology and prostate cancer ethnic disparity J Xiao, P Cohen, MC Stern, F Odedina, J Carpten, R Reams Carcinogenesis 39 (11), 1311-1319, 2018 | 35 | 2018 |
Subcellular fractionation for ERK activation upon mitochondrial-derived peptide treatment SJ Kim, J Xiao, P Cohen, K Yen JoVE (Journal of Visualized Experiments), e56496, 2017 | 6 | 2017 |
The regulation, roles, and mechanism of action of mitochondrial-derived-peptides (MDPs) in aging J Xiao University of Southern California, 2018 | 1 | 2018 |
Hormone MOTS-c improves metabolic dysfunction in obese mice SJ Kim, B Miller, HH Mehta, J Xiao, J Wan, TE Arpawong, K Yen, P Cohen | | 2019 |
Chaperone-like Activity of Mitochondrially-Derived Peptides Captures Diabetic Amyloid Seeds AK Okada, K Teranishi, F Lobo, J Xiao, HH Mehta, J Mario, KY Isas, ... Enhancing and Inhibiting Diabetic Amyloid Misfolding, 108, 2018 | | 2018 |
OR2-2: The mitochondrial peptide humanin has fasting mimetic activity leading to suppression of circulating IGF-I and increases in IGFBP-1 levels J Xiao, J Wan, H Mehta, YH Lue, Y Jia, R Swerdloff, C Wang, P Cohen Growth Hormone & IGF Research, S7-S8, 2014 | | 2014 |